野村直樹 (Naoki Nomura) - マイポータル

基本情報

所属: 北海道大学人獣共通感染症国際共同研究所国際展開推進部門特任助教

学位: 博士（獣医学）(2012年3月北海道大学)

研究者番号: 90897670
J-GLOBAL ID: 202001014385276114
researchmap会員ID: R000013509

論文

ARNAX is an ideal adjuvant for COVID-19 vaccines to enhance antigen-specific CD4+ and CD8+ T-cell responses and neutralizing antibody induction.

Tomomi Kawakita, Toshiki Sekiya, Yayoi Kameda, Naoki Nomura, Marumi Ohno, Chimuka Handabile, Akari Yamaya, Hideo Fukuhara, Yuki Anraku, Shunsuke Kita …

Journal of virology e0229024 2025年4月15日
Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine.

Chimuka Handabile, Marumi Ohno, Toshiki Sekiya, Naoki Nomura, Tomomi Kawakita, Mamiko Kawahara, Masafumi Endo, Tomohiro Nishimura, Minako Okumura, Shinsuke Toba …

Scientific reports 14(1) 4204-4204 2024年2月20日
Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire

Masashi Shingai, Sayaka Iida, Naoko Kawai, Mamiko Kawahara, Toshiki Sekiya, Marumi Ohno, Naoki Nomura, Chimuka Handabile, Tomomi Kawakita, Ryosuke Omori …

Journal of Virology 2024年2月7日
The elucidation of plasma lipidome profiles during severe influenza in a mouse model.

Marumi Ohno, Siddabasave Gowda B Gowda, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Shu-Ping Hui, Hiroshi Kida

Scientific reports 13(1) 14210-14210 2023年8月30日
Assessing the pyrogenicity of whole influenza virus particle vaccine in cynomolgus macaques.

Marumi Ohno, Masataka Sagata, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Masafumi Endo, Kazuhiko Kimachi, Saori Suzuki, Cong Thanh Nguyen, Misako Nakayama …

Vaccine 41(3) 787-794 2023年1月16日
Immunization with inactivated whole virus particle influenza virus vaccines improves the humoral response landscape in cynomolgus macaques

Brendon Y. Chua, Toshiki Sekiya, Marios Koutsakos, Naoki Nomura, Louise C. Rowntree, Thi H. O. Nguyen, Hayley A. McQuilten, Marumi Ohno, Yuki Ohara, Tomohiro Nishimura …

PLOS Pathogens 18(10) e1010891-e1010891 2022年10月7日
A high-affinity aptamer with base-appended base-modified DNA bound to isolated authentic SARS-CoV-2 strains wild-type and B.1.617.2 (delta variant).

Hirotaka Minagawa, Hirofumi Sawa, Tomoko Fujita, Shintaro Kato, Asumi Inaguma, Miwako Hirose, Yasuko Orba, Michihito Sasaki, Koshiro Tabata, Naoki Nomura …

Biochemical and biophysical research communications 614 207-212 2022年7月23日
Inactivated whole influenza virus particle vaccines induce neutralizing antibodies with an increase in immunoglobulin gene subclones of B-lymphocytes in cynomolgus macaques.

Masanori Shiohara, Saori Suzuki, Shintaro Shichinohe, Hirohito Ishigaki, Misako Nakayama, Naoki Nomura, Masashi Shingai, Toshiki Sekiya, Marumi Ohno, Sayaka Iida …

Vaccine 40(30) 4026-4037 2022年6月26日査読有り
Inactivated Whole Virus Particle Influenza Vaccine Induces Anti-Neuraminidase Antibodies That May Contribute to Cross-Protection against Heterologous Virus Infection.

Chimuka Handabile, Toshiki Sekiya, Naoki Nomura, Marumi Ohno, Tomomi Kawakita, Masashi Shingai, Hiroshi Kida

Vaccines 10(5) 2022年5月19日
Leptospira Is an Environmental Bacterium That Grows in Waterlogged Soil.

Yasutake Yanagihara, Sharon Y A M Villanueva, Naoki Nomura, Marumi Ohno, Toshiki Sekiya, Chimuka Handabile, Masashi Shingai, Hideaki Higashi, Shin-Ichi Yoshida, Toshiyuki Masuzawa …

Microbiology spectrum 10(2) e0215721 2022年4月27日
Critical role of oxidized LDL receptor-1 in intravascular thrombosis in a severe influenza mouse model

Marumi Ohno, Akemi Kakino, Toshiki Sekiya, Naoki Nomura, Masashi Shingai, Tatsuya Sawamura, Hiroshi Kida

Scientific Reports 11(1) 2021年12月
Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells.

Masashi Shingai, Naoki Nomura, Toshiki Sekiya, Marumi Ohno, Daisuke Fujikura, Chimuka Handabile, Ryosuke Omori, Yuki Ohara, Tomohiro Nishimura, Masafumi Endo …

Vaccine 39(29) 3940-3951 2021年6月29日
Updating the influenza virus library at Hokkaido University -It's potential for the use of pandemic vaccine strain candidates and diagnosis.

Naoki Nomura, Keita Matsuno, Masashi Shingai, Marumi Ohno, Toshiki Sekiya, Ryosuke Omori, Yoshihiro Sakoda, Robert G Webster, Hiroshi Kida

Virology 557 55-61 2021年5月
Potency of an Inactivated Influenza Vaccine against a Challenge with A/Swine/Missouri/A01727926/2015 (H4N6) in Mice for Pandemic Preparedness.

Hirotaka Hayashi, Norikazu Isoda, Enkhbold Bazarragchaa, Naoki Nomura, Keita Matsuno, Masatoshi Okamatsu, Hiroshi Kida, Yoshihiro Sakoda

Vaccines 8(4) 2020年12月16日
Immune profiling of influenza-specific B- and T-cell responses in macaques using flow cytometry-based assays.

Marios Koutsakos, Toshiki Sekiya, Brendon Y Chua, Thi Hoang Oanh Nguyen, Adam K Wheatley, Jennifer A Juno, Marumi Ohno, Naoki Nomura, Yuki Ohara, Tomohiro Nishimura …

Immunology and cell biology 99(1) 97-106 2020年8月1日
Influenza virus infection affects insulin signaling, fatty acid-metabolizing enzyme expressions, and the tricarboxylic acid cycle in mice.

Marumi Ohno, Toshiki Sekiya, Naoki Nomura, Taku Ji Daito, Masashi Shingai, Hiroshi Kida

Scientific reports 10(1) 10879-10879 2020年7月2日
Inactivated whole virus particle vaccine with potent immunogenicity and limited IL-6 induction is ideal for influenza.

Toshiki Sekiya, Edin J Mifsud, Marumi Ohno, Naoki Nomura, Mayumi Sasada, Daisuke Fujikura, Takuji Daito, Masashi Shingai, Yuki Ohara, Tomohiro Nishimura …

Vaccine 37(15) 2158-2166 2019年4月3日
Therapeutic efficacy of peramivir against H5N1 highly pathogenic avian influenza viruses harboring the neuraminidase H275Y mutation.

Masanori Kobayashi, Makoto Kodama, Takeshi Noshi, Ryu Yoshida, Takushi Kanazu, Naoki Nomura, Kosuke Soda, Norikazu Isoda, Masatoshi Okamatsu, Yoshihiro Sakoda …

Antiviral research 139 41-48 2017年3月
Co-ordinated ocular development from human iPS cells and recovery of corneal function.

Ryuhei Hayashi, Yuki Ishikawa, Yuzuru Sasamoto, Ryosuke Katori, Naoki Nomura, Tatsuya Ichikawa, Saori Araki, Takeshi Soma, Satoshi Kawasaki, Kiyotoshi Sekiguchi …

Nature 531(7594) 376-80 2016年3月17日
The genetic and antigenic diversity of avian influenza viruses isolated from domestic ducks, muscovy ducks, and chickens in northern and southern Vietnam, 2010-2012.

Masatoshi Okamatsu, Tatsuya Nishi, Naoki Nomura, Naoki Yamamoto, Yoshihiro Sakoda, Kenji Sakurai, Huy Duc Chu, Long Pham Thanh, Long Van Nguyen, Nam Van Hoang …

Virus genes 47(2) 317-29 2013年10月

もっとみる

MISC

Selecting and using the appropriate influenza vaccine for each individual

Toshiki Sekiya, Marumi Ohno, Naoki Nomura, Chimuka Handabile, Masashi Shingai, David C. Jackson, Lorena E. Brown, Hiroshi Kida

Viruses 13(6) 2021年6月
インフルエンザウイルスライブラリーを活用したパンデミックインフルエンザ対策

野村直樹, 新開大史, 松野啓太, 関屋俊輝, 関屋俊輝, 大野円実, 磯田典和, 迫田義博, 喜田宏, 喜田宏

日本獣医学会学術集会講演要旨集 164th (CD-ROM) 2021年

野村直樹

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