基本情報

所属
金沢大学人間社会研究域附属国際文化資源学研究センター 客員研究員
Trinity College Dublin Ussher Assistant Professor in Genomic Medicine
学位
生命科学(東京大学)

J-GLOBAL ID
201101065628007790

外部リンク

I received my Ph.D. at The University of Tokyo in 2010 with a focus on the evolutionary model in which high risk variants associated with Crohn's disease at the NOD2 locus may have exclusively spread into European populations by natural selection. As a postdoctoral researcher, I first joined The Institute of Statistical Mathematics from 2011 to 2014 where I was awarded a competitive Research Fellowship of the Japan Society for the Promotion of Science (JSPS) for Young Scientists and developed a new statistical method that incorporates kernel methods into Approximate Bayesian Computation (kernel ABC). I obtained further postdoctoral training on experimental aspects of functional genomics at The University of Chicago from 2013 to 2016 as JSPS Overseas Research Fellow. During this training, I have acquired expertise in population and functional genomics to develop statistical approaches for understanding selective pressures on immunity genes and to connect genetic polymorphisms to their functional consequences in the immune system. My general area of research interest is in applying high-throughput sequencing technology to understanding impacts of human evolution on biological roles of genetic variants associated with complex disease. I am currently leading two major projects: one is modern and ancient human genomics on the history of peopling into East Eurasia and Americas, and the other is gene by environment interactions (GEIs) that result in dysregulation of host immune response to commensal bacterial flora and contribute to the susceptibility to inflammatory bowel diseases (IBD).

論文

  32

MISC

  2

書籍等出版物

  5

講演・口頭発表等

  11