中原剛士 (Takeshi Nakahara) - マイポータル

基本情報

所属: 九州大学大学院医学研究院教授

研究者番号: 40529848
J-GLOBAL ID: 202401017040319994
researchmap会員ID: R000069654

論文

205

Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2024.

Hidehisa Saeki, Yukihiro Ohya, Hirokazu Arakawa, Susumu Ichiyama, Toshio Katsunuma, Norito Katoh, Akio Tanaka, Hideaki Tanizaki, Yuichiro Tsunemi, Takeshi Nakahara …

Allergology international : official journal of the Japanese Society of Allergology 74(2) 210-221 2025年4月
English version of clinical practice guidelines for the management of atopic dermatitis 2024.

Hidehisa Saeki, Yukihiro Ohya, Hirokazu Arakawa, Susumu Ichiyama, Toshio Katsunuma, Norito Katoh, Akio Tanaka, Hideaki Tanizaki, Yuichiro Tsunemi, Takeshi Nakahara …

The Journal of dermatology 52(2) e70-e142 2025年2月
Extracellular ATP Contributes to Barrier Function and Inflammation in Atopic Dermatitis: Potential for Topical Treatment of Atopic Dermatitis by Targeting Extracellular ATP.

Kazuhiko Yamamura, Fumitaka Ohno, Shu Yotsumoto, Yuki Sato, Nanae Kimura, Kiichiro Nishio, Keiichi Inoue, Toshio Ichiki, Yoko Kuba-Fuyuno, Kei Fujishima …

International journal of molecular sciences 25(22) 2024年11月15日
Biomarkers and patient-related factors associated with clinical outcomes in dupilumab-treated atopic dermatitis.

Makiko Kido-Nakahara, Daisuke Onozuka, Kenji Izuhara, Hidehisa Saeki, Satoshi Nunomura, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko …

The journal of allergy and clinical immunology. Global 3(4) 100317-100317 2024年11月
Prurigo chronica multiformis: Expert consensus of the Japanese Dermatological Association

Takahiro Satoh, Hiroyuki Murota, Yumi Aoyama, Takashi Hashimoto, Yozo Ishiuji, Yutaka Hatano, Takeshi Nakahara, Kenji Kabashima, Kenji Takamori, Ichiro Katayama

The Journal of Dermatology 51(11) 2024年10月11日
Cytokine profile of the stratum corneum in atopic dermatitis lesions differs between the face and the trunk.

Makiko Kido-Nakahara, Takahito Chiba, Yuta Mizusawa, Yuko Higashi, Atsuko Ibusuki, Satomi Igawa, Yumi Murakami, Hiroshi Matsunaka, Yoko Kuba-Fuyuno, Gaku Tsuji …

Allergology international : official journal of the Japanese Society of Allergology 2024年9月26日
Dupilumab in Adults With Moderate to Severe Atopic Dermatitis: A 5-Year Open-Label Extension Study.

Lisa A Beck, Robert Bissonnette, Mette Deleuran, Takeshi Nakahara, Ryszard Galus, Anna Coleman, Guy Gherardi, Jing Xiao, Robert Dingman, Christine Xu …

JAMA dermatology 160(8) 805-812 2024年8月1日
Real-world safety and efficacy of biologics in elderly patients with psoriasis: A multicenter observational study.

Chika Ohata, Hisataka Anezaki, Tetsuji Yanase, Eri Katayama, Sakae Kaneko, Kanami Saito, Mariko Yamane, Sei Nakamaru, Noriko Tsuruta, Fusako Okazaki …

The Journal of dermatology 2024年7月19日
Difamilast, a Topical Phosphodiesterase 4 Inhibitor, Produces Soluble ST2 via the AHR-NRF2 Axis in Human Keratinocytes.

Gaku Tsuji, Ayako Yumine, Koji Kawamura, Masaki Takemura, Makiko Kido-Nakahara, Kazuhiko Yamamura, Takeshi Nakahara

International journal of molecular sciences 25(14) 2024年7月19日
Proposal of a cutaneous lupus erythematosus-like keratinocyte model in vitro under local conditions using interferon-alpha and Poly I:C and its use in examining the therapeutic effects of tyrosine kinase 2 inhibitor.

Yoko Kuba-Fuyuno, Makiko Kido-Nakahara, Gaku Tsuji, Sawako Sakai, Takeshi Nakahara

The Journal of dermatology 51(7) 1031-1033 2024年7月
Induction of Semaphorin 3A by Resveratrol and Pinostilbene via Activation of the AHR-NRF2 Axis in Human Keratinocytes.

Gaku Tsuji, Ayako Yumine, Koji Kawamura, Masaki Takemura, Takeshi Nakahara

Antioxidants (Basel, Switzerland) 13(6) 2024年6月17日
A case of xeroderma pigmentosum group C with rare compound heterozygous mutations.

Kozo Kawaguchi, Makiko Kido-Nakahara, Yoko Kuba-Fuyuno, Gaku Tsuji, Ryusuke Ono, Chikako Nishigori, Takeshi Nakahara

European journal of dermatology : EJD 34(2) 226-228 2024年4月1日
NECTIN4-targeted antibody-drug conjugate is a potential therapeutic option for extramammary Paget disease.

Yuka Tanaka, Takamichi Ito, Maho Murata, Keiko Tanegashima, Yumiko Kaku-Ito, Takeshi Nakahara

Experimental dermatology 33(3) e15049 2024年3月
Physiological effects of appropriate washing on xerotic skin

Satoshi Takeuchi, Yumi Murakami, Hiroshi Matsunaka, Takeshi Nakahara, Masutaka Furue

Journal of Cosmetic Dermatology 23(3) 876-885 2024年3月
The Therapeutic Aryl Hydrocarbon Receptor–Modulating Agent Tapinarof Regulates SEMA3A Expression in Human Keratinocytes through NRF2

Gaku Tsuji, Ayako Yumine, Kazuhiko Yamamura, Masaki Takemura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

Journal of Investigative Dermatology 144(3) 710-713.e8 2024年3月
FOXM1: a new therapeutic target of extramammary Paget disease.

Takamichi Ito, Yuka Tanaka, Yumiko Kaku-Ito, Yoshinao Oda, Takeshi Nakahara

Scientific reports 14(1) 4048-4048 2024年2月19日
The ability of biomarkers to assess the severity of atopic dermatitis

Takeshi Nakahara, Daisuke Onozuka, Satoshi Nunomura, Hidehisa Saeki, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko, Eishin Morita …

Journal of Allergy and Clinical Immunology: Global 3(1) 2024年2月
Pigmented epithelioid melanocytoma arising from a teratoma of a Carney complex patient

Toshio Ichiki, Takamichi Ito, Hiroko Oishi, Kiyoko Kato, Yoshinao Oda, Takeshi Nakahara

Journal of Obstetrics and Gynaecology Research 50(2) 266-269 2024年2月
Accessory Breast Cancer in the Right Axilla with Dermoscopic Images.

Takuma Matsunaga, Yuichi Yoshida, Takeshi Nakahara, Osamu Yamamoto

Indian journal of dermatology 69(3) 276-277 2024年
Physicians’ perspectives and practice in atopic dermatitis management: a cross-sectional online survey in Japan

Sakae Kaneko, Takeshi Nakahara, Hiroyuki Murota, Akio Tanaka, Yoko Kataoka, Takeyasu Kakamu, Hiroyuki Kanoh, Yuko Watanabe, Norito Katoh

Journal of Cutaneous Immunology and Allergy 7 2024年

もっとみる

MISC

Exploring patient background and biomarkers associated with the development of dupilumab-associated conjunctivitis and blepharitis

Makiko Kido-Nakahara, Daisuke Onozuka, Kenji Izuhara, Hidehisa Saeki, Satoshi Nunomura, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko …

Allergology International 73(2) 332-334 2024年4月
Evaluating the usefulness of the Atopic Dermatitis Control Tool for assessing disease control in individuals with atopic dermatitis in Japan

Takeshi Nakahara, Hiroyuki Fujita, Yuki Tajima, Kazuhiko Arima

British Journal of Dermatology 190(1) 123-125 2024年1月
Regulatory Mechanism of the IL-33–IL-37 Axis via Aryl Hydrocarbon Receptor in Atopic Dermatitis and Psoriasis

Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

International Journal of Molecular Sciences 24(19) 2023年10月
乾癬患者におけるHTLV-1抗体陽性率と治療選択に与える影響を明らかにするための多施設共同観察研究

米倉健太郎, 鶴田紀子, 宮城拓也, 小池雄太, 東裕子, 桑代麻希, 中原剛士, 大畑千佳, 金子栄, 山口道也 …

西日本皮膚科 85(3) 241-241 2023年6月
Prevalence of human T-lymphotropic virus type I in patients with psoriasis and its effect on treatment choice: A multicenter observational study

Kentaro Yonekura, Noriko Tsuruta, Takuya Miyagi, Yuta Koike, Yuko Higashi, Takeshi Nakahara, Chika Ohata, Sakae Kaneko, Michiya Yamaguchi, Kanami Saito …

Journal of Dermatological Science 110(3) 103-106 2023年6月
Novel Therapeutic Targets for the Treatment of Atopic Dermatitis

Gaku Tsuji, Kazuhiko Yamamura, Koji Kawamura, Makiko Kido-Nakahara, Takamichi Ito, Takeshi Nakahara

Biomedicines 11(5) 2023年5月
Nail Apparatus Melanoma: Current Management and Future Perspectives

Takamichi Ito, Hiroki Hashimoto, Yumiko Kaku-Ito, Yuka Tanaka, Takeshi Nakahara

Journal of Clinical Medicine 12(6) 2023年3月
Exploring biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab (B-PAD study)

Takeshi Nakahara, Kenji Izuhara, Daisuke Onozuka, Hidehisa Saeki, Satoshi Nunomura, Motoi Takenaka, Mai Matsumoto, Yoko Kataoka, Rai Fujimoto, Sakae Kaneko …

Clinical and Experimental Allergy 53(2) 233-238 2023年2月
A Possible Therapeutic Strategy for Atopic Dermatitis Based on the Recent Findings of IL-4/IL-13

Takeshi Nakahara, Gaku Tsuji, Sarina Kurimoto, Kenji Izuhara

Nishinihon Journal of Dermatology 85(1) 5-15 2023年
KEY POINTS FOR EVALUATING ATOPIC DERMATITIS

Takeshi Nakahara

Japanese Journal of Allergology 72(5) 437-442 2023年
Severity strata of patient-oriented eczema measure scores in patients with atopic dermatitis in Mongolia

Dugarmaa Ulzii, Takeshi Nakahara, Masutaka Furue, Khandsuren Byamba, Makiko Kido-Nakahara

International Journal of Dermatology 61(12) e469-e472 2022年12月
Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis

Kazufumi Kunimura, Kazuhiko Yamamura, Takeshi Nakahara, Makiko Kido-Nakahara, Takehito Uruno, Yoshinori Fukui

Allergy: European Journal of Allergy and Clinical Immunology 77(12) 3670-3672 2022年12月
Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2021

Hidehisa Saeki, Yukihiro Ohya, Junichi Furuta, Hirokazu Arakawa, Susumu Ichiyama, Toshio Katsunuma, Norito Katoh, Akio Tanaka, Yuichiro Tsunemi, Takeshi Nakahara …

Allergology International 71(4) 448-458 2022年10月
The Dawn of a New Era in Atopic Dermatitis Treatment

Kazuhiko Yamamura, Takeshi Nakahara

Journal of Clinical Medicine 11(20) 2022年10月
Atopic dermatitis refractory to dupilumab but markedly responsive to baricitinib

Ryoma Honda, Asako Suenaga, Takeshi Nakahara, Satoko Shibata-Kikuchi

European Journal of Dermatology 32(5) 649-650 2022年9月
Impact of physicians' clinical experience and workplace on patients' care of urticaria in Japan: A sub-analysis of a nation-wide cross-sectional web questionnaire survey

Shunsuke Takahagi, Akiko Kamegashira, Naoko Inomata, Atsushi Fukunaga, Takeshi Nakahara, Koremasa Hayama, Michihiro Hide

Journal of Cutaneous Immunology and Allergy 5(3) 106-108 2022年6月
Efficacy of Dupilumab for Atopic Dermatitis According to Clinical Course and Clinical Findings: A Multicentre Retrospective Study

Takeshi Nakahara, Makiko Kido-Nakahara, Daisuke Onozuka, Sawako Sakai, Tomoko Hirose, Nobutoshi Take, Akiko Sugiyama, Kayo Harada, Gaku Tsuji, Satoko Kikuchi …

Acta Dermato-Venereologica 101(11) 2021年11月
Basics and recent advances in the pathophysiology of atopic dermatitis

Takeshi Nakahara, Makiko Kido-Nakahara, Gaku Tsuji, Masutaka Furue

Journal of Dermatology 48(2) 130-139 2021年2月
Repeated infliximab injection may shift delayed infusion reactions to acute infusion reactions in patients with psoriasis

Ayaka Eto, Takeshi Nakahara, Masutaka Furue

Journal of Dermatology 48(1) e41-e42 2021年1月
Pathogenic implication of epidermal scratch injury in psoriasis and atopic dermatitis

Kazuhisa Furue, Dugarmaa Ulzii, Yuka Tanaka, Takamichi Ito, Gaku Tsuji, Makiko Kido-Nakahara, Takeshi Nakahara, Masutaka Furue

Journal of Dermatology 47(9) 979-988 2020年9月1日

もっとみる

共同研究・競争的資金等の研究課題

アトピー性皮膚炎における細胞外ATPを介した細胞間相互作用の解析と治療応用

日本学術振興会科学研究費助成事業基盤研究(C) 2024年4月 - 2027年3月

中原剛士
かゆみ・炎症・バリアからみたアトピー性皮膚炎におけるMAPKの役割解明と治療応用

日本学術振興会科学研究費助成事業基盤研究(C) 2021年4月 - 2024年3月

中原剛士
乾癬・アトピー性皮膚炎の病態におけるエンドセリン－１の役割の解明とその治療応用

日本学術振興会科学研究費助成事業基盤研究(C) 2018年4月 - 2021年3月

中原剛士
カペシタビンによる手足症候群の重症化回避を目指した保湿ケア技術の確立

日本学術振興会科学研究費助成事業奨励研究 2019年 - 2019年

槇原洋子, 渡邊裕之, 辻敏和, 中原剛士, 江頭伸昭
マウス悪性黒色腫発育早期の腫瘍浸潤樹状細胞の解析－経時的変化とその意義－

日本学術振興会科学研究費助成事業若手研究(B) 2013年4月 - 2015年3月

中原剛士
皮膚悪性腫瘍微小環境が樹状細胞を介した免疫反応に与える影響の解析

日本学術振興会科学研究費助成事業若手研究(B) 2011年 - 2012年

中原剛士