Tomoya Nakamachi

J-GLOBAL         Last updated: May 16, 2019 at 10:52
 
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Name
Tomoya Nakamachi
E-mail
nakamachisci.u-toyama.ac.jp
Affiliation
University of Toyama
Research funding number
30433840

Research Areas

 
 

Academic & Professional Experience

 
Dec 2017
 - 
Today
Junior Associate Professor, Department of Biology (Science), University of Toyama
 
Dec 2013
 - 
Nov 2017
Professor (Assistant), Department of Biology (Science), University of Toyama
 
May 2010
 - 
Dec 2013
Professor (Assistant), Center for Biotechnology, Showa University
 
Apr 2006
 - 
Apr 2010
PostDoc Position, Department of Anatomy, Showa University School of Medicine
 
Apr 2004
 - 
Dec 2005
Medical Resident Specialist (predoctral fellow), Department of Medicine, Tulane University
 

Education

 
Apr 2002
 - 
Mar 2006
Department of Anatomy, Showa University School of Medicine
 
Apr 2000
 - 
Mar 2002
Biology, Laboratory of Regulatory Biology, Graduate School of Science and Engineering, University of Toyama
 
Apr 1996
 - 
Mar 2000
Department of Biology, Faculty of Science, University of Toyama
 

Awards & Honors

 
Mar 2017
Encouragement Award, Japanese Association of Anatomist
 
May 2016
Matsuo investigator Award, Japan Society for GPCR Research
 
Jan 2009
Travel Award, 17th international Symposium on Regulatory Peptides
 
Aug 2008
Young Investigator Award, Japan Society of Neuroendocrinology
 
Sep 2007
Travel Award, 8th International Symposium for VIP, PACAP and Related Peptides
 
Sep 2006
Young Investigator Award, The 16th International Symposium on Regulatory Peptides
 
Jun 2006
Young Investigator Award, International Congress of Neuroendocrinology
 
Sep 2003
Best poster award, Half-day Symposium on GPCRs
 
Dec 2001
Best poster award, 26th Congress of the Japan Society for Comparative Endocrinology
 

Published Papers

 
Sachuriga, Iinuma N, Shibata H, Yoshida D, Konno N, Nakamachi T, Matsuda K
Journal of neuroendocrinology   31(1) e12667   Jan 2019   [Refereed]
Nakamachi T, Tanigawa A, Konno N, Shioda S, Matsuda K
Frontiers in endocrinology   10 227   2019   [Refereed]
Shioda S, Takenoya F, Hirabayashi T, Wada N, Seki T, Nonaka N, Nakamachi T
Journal of molecular neuroscience : MN      Jun 2018   [Refereed]
Nakamachi T, Kamata E, Tanigawa A, Konno N, Shioda S, Matsuda K
Peptides   103 40-47   May 2018   [Refereed]
Hirabayashi T, Nakamachi T, Shioda S
The journal of headache and pain   19(1) 28   Apr 2018   [Refereed]
S. Sasaki, S. Sasaki, J. Watanabe, H. Ohtaki, M. Matsumoto, N. Murai, T. Nakamachi, J. Hannibal, J. Fahrenkrug, H. Hashimoto, H. Hashimoto, H. Hashimoto, H. Watanabe, H. Sueki, K. Honda, A. Miyazaki, S. Shioda
British Journal of Dermatology   176 413-422   Feb 2017
© 2016 British Association of Dermatologists Background: Sweat secretion is the major function of eccrine sweat glands; when this process is disturbed (paridrosis), serious skin problems can arise. To elucidate the causes of paridrosis, an improve...
Matsuda K, Matsumura K, Shimizu SS, Nakamachi T, Konno N
Frontiers in neuroscience   11 176   Apr 2017   [Refereed]
Sakamoto T, Yoshiki M, Takahashi H, Yoshida M, Ogino Y, Ikeuchi T, Nakamachi T, Konno N, Matsuda K, Sakamoto H
Scientific reports   6 37991   Nov 2016   [Refereed]
Shioda S, Takenoya F, Wada N, Hirabayashi T, Seki T, Nakamachi T
Anatomical science international   91(4) 313-324   Sep 2016   [Refereed]
Matoba Y, Nonaka N, Takagi Y, Imamura E, Narukawa M, Nakamachi T, Shioda S, Banks WA, Nakamura M
Anatomical record (Hoboken, N.J. : 2007)   299(9) 1293-1299   Sep 2016   [Refereed]
Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, Sasaki S, Xu Z, Hashimoto H, Seki T, Miyazaki A, Shioda S
Journal of molecular neuroscience : MN   59(2) 270-279   Jun 2016   [Refereed]
Nakamachi T, Ohtaki H, Seki T, Yofu S, Kagami N, Hashimoto H, Shintani N, Baba A, Mark L, Lanekoff I, Kiss P, Farkas J, Reglodi D, Shioda S
Nature communications   7 12034   Jun 2016   [Refereed]
Shioda S, Nakamachi T
Peptides   72 202-207   Oct 2015   [Refereed]
Tomiyama S, Nakamachi T, Uchiyama M, Matsuda K, Konno N
General and comparative endocrinology   216 54-63   May 2015   [Refereed]
Hori M, Shibato J, Nakamachi T, Rakwal R, Ogawa T, Shioda S, Numazawa S
Genomics data   3 148-154   Mar 2015   [Refereed]
Karki P, Kurihara T, Nakamachi T, Watanabe J, Asada T, Oyoshi T, Shioda S, Yoshimura M, Arita K, Miyata A
Molecular pain   11 6   Feb 2015   [Refereed]
Tsumuraya T, Ohtaki H, Song D, Sato A, Watanabe J, Hiraizumi Y, Nakamachi T, Xu Z, Dohi K, Hashimoto H, Atsumi T, Shioda S
Journal of neuroinflammation   12 35   Feb 2015   [Refereed]
Hori M, Nakamachi T, Shibato J, Rakwal R, Shioda S, Numazawa S
Microarrays (Basel, Switzerland)   4(1) 2-24   Jan 2015   [Refereed]
Yoshikawa A, Nakamachi T, Shibato J, Rakwal R, Shioda S
International journal of molecular sciences   15(12) 22492-22517   Dec 2014   [Refereed]
Tsuchida M, Nakamachi T, Sugiyama K, Tsuchikawa D, Watanabe J, Hori M, Yoshikawa A, Imai N, Kagami N, Matkovits A, Atsumi T, Shioda S
Journal of molecular neuroscience : MN   54(3) 380-387   Nov 2014   [Refereed]
Nakamachi T, Sugiyama K, Watanabe J, Imai N, Kagami N, Hori M, Arata S, Shioda S
Journal of molecular neuroscience : MN   54(3) 388-394   Nov 2014   [Refereed]
Kigawa Y, Miyazaki T, Lei XF, Nakamachi T, Oguchi T, Kim-Kaneyama JR, Taniyama M, Tsunawaki S, Shioda S, Miyazaki A
Arteriosclerosis, thrombosis, and vascular biology   34(11) 2413-2420   Nov 2014   [Refereed]
Shimizu S, Nakamachi T, Konno N, Matsuda K
Peptides   59 79-82   Sep 2014   [Refereed]
Hori M, Nakamachi T, Shibato J, Rakwal R, Tsuchida M, Shioda S, Numazawa S
International journal of molecular sciences   15(9) 17014-17034   Sep 2014   [Refereed]
Nakamachi T, Shibata H, Sakashita A, Iinuma N, Wada K, Konno N, Matsuda K
Hormones and behavior   66(2) 317-323   Jul 2014   [Refereed]
K. Nakamura, K. Nakamura, T. Nakamachi, T. Nakamachi, K. Endo, K. Ito, T. Machida, T. Oka, M. Hori, K. Ishizaka, S. Shioda
Andrologia   46 465-471   Jan 2014
Summary: Pituitary adenylate cyclase-activating peptide (PACAP) is a neuropeptide expressed in the central nervous system and peripheral organs. Previous studies revealed the role and distribution of PACAP in the rodent testis, however, its presen...
Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Tsuchida M, Yoshikawa A, Matkovits A, Kagami N, Imai N, Fujisaka S, Usui I, Tobe K, Koide R, Takahashi H, Shioda S
Journal of molecular neuroscience : MN   51(2) 493-502   Oct 2013   [Refereed]
Saito H, Nakamachi T, Inoue K, Ikeda R, Kitamura K, Minamino N, Shioda S, Miyata A
The Journal of endocrinology   217(2) 141-150   May 2013   [Refereed]
Arata S, Nakamachi T, Onimaru H, Hashimoto H, Shioda S
The European journal of neuroscience   37(3) 407-416   Feb 2013   [Refereed]
Nakamachi T, Farkas J, Kagami N, Wada Y, Hori M, Tsuchikawa D, Tsuchida M, Yoshikawa A, Imai N, Hosono T, Atrata S, Shioda S
Acta neurochirurgica. Supplement   118 55-59   2013   [Refereed]
Watanabe J, Nakamachi T, Ohtaki H, Naganuma A, Shioda S, Nakajo S
The Journal of toxicological sciences   38(6) 931-935   Mar 2013   [Refereed]
Nakamachi T, Tsuchida M, Kagami N, Yofu S, Wada Y, Hori M, Tsuchikawa D, Yoshikawa A, Imai N, Nakamura K, Arata S, Shioda S
Journal of molecular neuroscience : MN   48(3) 518-525   Nov 2012   [Refereed]
Tsuchikawa D, Nakamachi T, Tsuchida M, Wada Y, Hori M, Farkas J, Yoshikawa A, Kagami N, Imai N, Shintani N, Hashimoto H, Atsumi T, Shioda S
Journal of molecular neuroscience : MN   48(3) 508-517   Nov 2012   [Refereed]
Hori M, Nakamachi T, Rakwal R, Shibato J, Ogawa T, Aiuchi T, Tsuruyama T, Tamaki K, Shioda S
Journal of neuroinflammation   9 256   Nov 2012   [Refereed]
Nonaka N, Farr SA, Nakamachi T, Morley JE, Nakamura M, Shioda S, Banks WA
Peptides   36(2) 168-175   Aug 2012   [Refereed]
Miyamoto A, Takami M, Matsumoto A, Mochizuki A, Yamada T, Tachi K, Shibuya I, Nakamachi T, Shioda S, Baba K, Inoue T, Miyamoto Y, Yim M, Kamijo R
Cytotechnology   64(3) 331-339   May 2012   [Refereed]
Hori M, Nakamachi T, Rakwal R, Shibato J, Nakamura K, Wada Y, Tsuchikawa D, Yoshikawa A, Tamaki K, Shioda S
Disease models & mechanisms   5(2) 270-283   Mar 2012   [Refereed]
Nakamachi T, Matkovits A, Seki T, Shioda S
Frontiers in endocrinology   3 145   Nov 2012   [Refereed]
Ogawa T, Wakai C, Saito T, Murayama A, Mimura Y, Youfu S, Nakamachi T, Kuwagata M, Satoh K, Shioda S
Congenital anomalies   51(2) 70-79   Jun 2011   [Refereed]
S. Tanaka, H. Kondo, K. Kanda, T. Ashino, T. Nakamachi, K. Sekikawa, Y. Iwakura, S. Shioda, S. Numazawa, T. Yoshida
Journal of Neuroscience Research   89 506-514   Apr 2011
We have developed an animal model of learning and memory impairment associated with activation of microglia in the mouse brain. Injection of lipopolysaccharide into the CA1 region of the mouse hippocampus resulted in an increased production of inf...
Mihara Y, Dohi K, Yofu S, Nakamachi T, Ohtaki H, Shioda S, Aruga T
Journal of molecular neuroscience : MN   43(2) 162-168   Feb 2011   [Refereed]
Nakamachi T, Nakamura K, Oshida K, Kagami N, Mori H, Watanabe J, Arata S, Yofu S, Endo K, Wada Y, Hori M, Tsuchikawa D, Kato M, Shioda S
Journal of molecular neuroscience : MN   43(1) 16-21   Jan 2011   [Refereed]
Seki T, Itoh H, Nakamachi T, Endo K, Wada Y, Nakamura K, Shioda S
Journal of molecular neuroscience : MN   43(1) 30-34   Jan 2011   [Refereed]
Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S
Journal of molecular neuroscience : MN   43(1) 22-29   Jan 2011   [Refereed]
Nakamachi T, Farkas J, Watanabe J, Ohtaki H, Dohi K, Arata S, Shioda S
Current pharmaceutical design   17(10) 973-984   2011   [Refereed]
Ohtaki H, Satoh A, Nakamachi T, Yofu S, Dohi K, Mori H, Ohara K, Miyamoto K, Hashimoto H, Shintani N, Baba A, Matsunaga M, Shioda S
Journal of molecular neuroscience : MN   42(3) 397-403   Nov 2010   [Refereed]
Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, Song D, Tsunawaki S, Shioda S, Aruga T
Journal of neuroinflammation   7 41   Jul 2010   [Refereed]
Mori H, Nakamachi T, Ohtaki H, Yofu S, Sato A, Endo K, Iso Y, Suzuki H, Takeyama Y, Shintani N, Hashimoto H, Baba A, Shioda S
Circulation journal : official journal of the Japanese Circulation Society   74(6) 1183-1190   Jun 2010   [Refereed]
Ohtaki H, Yofu S, Nakamachi T, Satoh K, Shimizu A, Mori H, Sato A, Iwakura Y, Matsunaga M, Shioda S
Journal of clinical biochemistry and nutrition   46(2) 93-104   Mar 2010   [Refereed]
Nakamachi T, Ohtaki H, Yofu S, Dohi K, Watanabe J, Mori H, Sato A, Hashimoto H, Shintani N, Baba A, Shioda S
Acta neurochirurgica. Supplement   106 43-46   Aug 2010   [Refereed]
Dohi K, Satoh K, Nakamachi T, Ohtaki H, Yofu S, Nakamura S, Shioda S, Aruga T
Acta neurochirurgica. Supplement   106 315-319   Aug 2010   [Refereed]
Watanabe J, Nakamachi T, Ogawa T, Naganuma A, Nakamura M, Shioda S, Nakajo S
The Journal of toxicological sciences   34(3) 315-325   Jun 2009   [Refereed]
Dogrukol-Ak D, Kumar VB, Ryerse JS, Farr SA, Verma S, Nonaka N, Nakamachi T, Ohtaki H, Niehoff ML, Edwards JC, Shioda S, Morley JE, Banks WA
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism   29(2) 411-422   Feb 2009   [Refereed]
Ohtaki H, Nakamachi T, Dohi K, Shioda S
Journal of molecular neuroscience : MN   36(1-3) 16-25   Nov 2008   [Refereed]
Seki T, Itoh H, Nakamachi T, Shioda S
Journal of molecular neuroscience : MN   36(1-3) 57-60   Nov 2008   [Refereed]
Shimakura S, Kojima K, Nakamachi T, Kageyama H, Uchiyama M, Shioda S, Takahashi A, Matsuda K
Peptides   29(8) 1432-1440   Aug 2008   [Refereed]
Senga F, Yin L, Karasuno H, Ohtaki H, Nakamachi T, Satoh K, Shioda S
Journal of clinical biochemistry and nutrition   42(3) 222-227   May 2008   [Refereed]
Shimakura S, Miura T, Maruyama K, Nakamachi T, Uchiyama M, Kageyama H, Shioda S, Takahashi A, Matsuda K
Hormones and behavior   53(2) 323-328   Feb 2008   [Refereed]
Dohi K, Ripley B, Fujiki N, Ohtaki H, Yamamoto T, Goto Y, Nakamachi T, Shioda S, Aruga T, Nishino S
Regulatory peptides   145(1-3) 60-64   Jan 2008   [Refereed]
Matsuno R, Ohtaki H, Nakamachi T, Watanabe J, Yofu S, Hayashi D, Takeda T, Nonaka N, Seki M, Nakamura M, Itabashi K, Shioda S
Regulatory peptides   145(1-3) 80-87   Jan 2008   [Refereed]
Nakamachi T, Ohtaki H, Yofu S, Dohi K, Watanabe J, Hayashi D, Matsuno R, Nonaka N, Itabashi K, Shioda S
Regulatory peptides   145(1-3) 88-95   Jan 2008   [Refereed]
Watanabe J, Nakamachi T, Matsuno R, Hayashi D, Nakamura M, Kikuyama S, Nakajo S, Shioda S
Peptides   28(9) 1713-1719   Sep 2007   [Refereed]
Ohtaki H, Takeda T, Dohi K, Yofu S, Nakamachi T, Satoh K, Hiraizumi Y, Miyaoka H, Matsunaga M, Shioda S
Neuroscience research   58(4) 349-355   Aug 2007   [Refereed]
Inoue H, Ohtaki H, Nakamachi T, Shioda S, Okada Y
Journal of neuroscience research   85(7) 1427-1435   May 2007   [Refereed]
Kenji Dohi, Kenji Dohi, Kazue Satoh, Tomoya Nakamachi, Sachiko Yofu, Keisuke Hiratsuka, Shunsuke Nakamura, Hirokazu Ohtaki, Toshikazu Yoshikawa, Seiji Shioda, Tohru Aruga
Antioxidants and Redox Signaling   9 281-287   Feb 2007
Edaravone (MCI-186) is a novel synthetic free radical scavenger intended to have neuroprotective effect against ischemic insult. It is currently used on patients with cerebral infarction. Here, we note beneficial pharmaceutical effects of edaravon...
Dohi K, Satoh K, Nakamachi T, Yofu S, Hiratsuka K, Nakamura S, Ohtaki H, Yoshikawa T, Shioda S, Aruga T
Antioxidants & redox signaling   9(2) 281-287   Feb 2007   [Refereed]
Kudo Y, Ohtaki H, Dohi K, Yin L, Nakamachi T, Endo S, Yofu S, Hiraizumi Y, Miyaoka H, Shioda S
Critical care medicine   34(11) 2820-2826   Nov 2006   [Refereed]
Dohi K, Satoh K, Mihara Y, Nakamura S, Miyake Y, Ohtaki H, Nakamachi T, Yoshikawa T, Shioda S, Aruga T
Journal of neurotrauma   23(11) 1591-1599   Nov 2006   [Refereed]
Li M, Cortez S, Nakamachi T, Batuman V, Arimura A
Cancer research   66(17) 8796-8803   Sep 2006   [Refereed]
Dohi K, Nishino S, Nakamachi T, Ohtaki H, Morikawa K, Takeda T, Shioda S, Aruga T
Neuropeptides   40(4) 245-250   Aug 2006   [Refereed]
Nakamachi T, Li M, Shioda S, Arimura A
Peptides   27(7) 1859-1864   Jul 2006   [Refereed]
Matsuda K, Maruyama K, Nakamachi T, Miura T, Shioda S
Annals of the New York Academy of Sciences   1070 417-421   Jul 2006   [Refereed]
Shioda S, Ohtaki H, Nakamachi T, Dohi K, Watanabe J, Nakajo S, Arata S, Kitamura S, Okuda H, Takenoya F, Kitamura Y
Annals of the New York Academy of Sciences   1070 550-560   Jul 2006   [Refereed]
H. Ohtaki, T. Nakamachi, K. Dohi, S. Yofu, K. Hodoyama, M. Matsunaga, T. Aruga, S. Shioda
Acta neurochirurgica. Supplement.   96 249-253   Jun 2006
A stable model of neuronal damage after ischemia is needed in mice to enable progression of transgenic strategies. We performed transient global ischemia induced by common carotid artery occlusions with and without maintaining normal rectal temper...
Ohtaki H, Nakamachi T, Dohi K, Aizawa Y, Takaki A, Hodoyama K, Yofu S, Hashimoto H, Shintani N, Baba A, Kopf M, Iwakura Y, Matsuda K, Arimura A, Shioda S
Proceedings of the National Academy of Sciences of the United States of America   103(19) 7488-7493   May 2006   [Refereed]
T. Nakamachi, Kouhei Matsuda, K. Maruyama, T. Miura, M. Uchiyama, H. Funahashi, T. Sakurai, S. Shioda
Journal of Neuroendocrinology   18 290-297   Apr 2006
Orexin is a hypothalamic neuropeptide that is implicated in the regulation of feeding behaviour and the sleep-wakefulness cycle in mammals. However, in spite of a growing body of knowledge concerning orexin in mammals, the orexin system and its fu...
Pan W, Ding Y, Yu Y, Ohtaki H, Nakamachi T, Kastin AJ
Experimental neurology   198(1) 222-233   Mar 2006   [Refereed]
H. Ohtaki, T. Nakamachi, K. Dohi, K. Dohi, S. Yofu, S. Yofu, K. Hodoyama, M. Matsunaga, T. Aruga, S. Shioda
Acta Neurochirurgica, Supplementum   249-253   Jan 2006
A stable model of neuronal damage after ischemia is needed in mice to enable progression of transgenic strategies. We performed transient global ischemia induced by common carotid artery occlusions with and without maintaining normal rectal temper...
Narita M, Nagumo Y, Hashimoto S, Narita M, Khotib J, Miyatake M, Sakurai T, Yanagisawa M, Nakamachi T, Shioda S, Suzuki T
The Journal of neuroscience : the official journal of the Society for Neuroscience   26(2) 398-405   Jan 2006   [Refereed]
Matsuda K, Maruyama K, Nakamachi T, Miura T, Uchiyama M, Shioda S
Peptides   26(9) 1611-1616   Sep 2005   [Refereed]
Hirokazu Ohtaki, Hirokazu Ohtaki, Kenji Dohi, Tomoya Nakamachi, Sachiko Yofu, Sakura Endo, Yoshifumi Kudo, Seiji Shioda, Seiji Shioda
Acta Histochemica et Cytochemica   38 99-106   May 2005
Cerebrovascular disease is the third leading cause of death in the industrialized world and is also a major cause of long-lasting disability. The development of gene deficient and transgenic mice has recently aided in research into and development...
Nakamachi T, Endo S, Ohtaki H, Yin L, Kenji D, Kudo Y, Funahashi H, Matsuda K, Shioda S
Regulatory peptides   126(1-2) 49-54   Mar 2005   [Refereed]
Ogawa T, Nakamachi T, Ohtaki H, Hashimoto H, N S, Baba A, Watanabe J, Kikuyama S, Shioda S
Regulatory peptides   126(1-2) 103-108   Mar 2005   [Refereed]
Ohtaki H, Dohi K, Yofu S, Nakamachi T, Kudo Y, Endo S, Aruga T, Goto N, Watanabe J, Kikuyama S, Shioda S
Regulatory peptides   123(1-3) 61-67   Dec 2004   [Refereed]
Yin L, Ohtaki H, Nakamachi T, Kudo Y, Makino R, Shioda S
Neuroscience letters   370(1) 30-35   Nov 2004   [Refereed]
Ohtaki H, Yin L, Nakamachi T, Dohi K, Kudo Y, Makino R, Shioda S
Neuroscience letters   368(2) 162-166   Sep 2004   [Refereed]
Hirokazu Ohtaki, Hirokazu Ohtaki, Sakura Endo, Tomoya Nakamachi, Li Yin, Kenji Dohi, Yoshifumi Kudo, Yumiko Iwai, Masaji Matsunaga, Noboru Goto, Seiji Shioda, Seiji Shioda
Acta Histochemica et Cytochemica   36 385-391   Nov 2003
Molecular mediators such as intercellular adhesion molecule-1 (ICAM-1) have been implicated in the induction of neuronal damage after ischemia/reperfusion. However, the time-dependent expression of ICAM-1 after transient ischemia and the relative ...
H. Ohtaki, H. Ohtaki, A. Takaki, L. Yin, L. Yin, K. Dohi, T. Nakamachi, M. Matsunaga, R. Horai, M. Asano, Y. Iwakura, S. Shioda, S. Shioda
Acta Neurochirurgica, Supplementum   191-194   Jan 2003
Interleukin-l (IL-1) contributes to ischemic neurodegeneration. However, the mechanisms regulating action of IL-1 are still poorly understood. In order to clarify this central issue, mice that were gene deficient both IL-1α and β (IL-1 KO) and wil...
H. Ohtaki, H. Ohtaki, S. Mori, S. Mori, T. Nakamachi, K. Dohi, L. Yin, L. Yin, S. Endo, Y. Okada, Y. Okada, S. Shioda, S. Shioda
Acta Neurochirurgica, Supplementum   97-100   Jan 2003
For the first time we set up a new model for global ischemia in the infant mice, and time-dependent changes of the blood-brain barrier (BBB) disruption and neuronal cell death were investigated in detail. Infant C57/BI6 mice (postnatal 13 days) we...
S. Shioda, S. Shioda, L. Yin, L. Yin, H. Ohtaki, H. Ohtaki, T. Nakamachi, K. Dohi, Y. Iwai, H. Funahashi, R. Makino
Acta Neurochirurgica, Supplementum   93-96   Jan 2003
It has been considered that tumor necrosis factor a (TNFα) is participated in the Alzheimer's, and Parkinson's diseases, brain injury and brain ischemia. However, expression of TNFα after brain ischemia has not been demonstrated in detail. Therefo...

Misc

 
MATSUDA KOUHEI, NAKAMACHI TOMOYA, KONNO NORIFUMI
NIPPON SUISAN GAKKAISHI   81(5) 870-870   Jan 2015
松田 恒平, 中町 智哉, 今野 紀文
海洋と生物   37(6) 605-613   Dec 2015
KUSUYAMA Taro, GESHI Eiichi, KATAGIRI Takashi, NAKAMACHI Tomoya, OHTAKI Hirokazu, SHIODA Seiji, SEKIKAWA Kenji, SUZUKI Hiroshi, SHOJI Makoto, SATO Ryuji, OMORI Yasutoshi, SODA Teruko, SATO Takatoshi, ISO Yoshitaka, KOBA Shinji
Journal of The Showa Medical Association   67(2) 126-133   Apr 2007
TNF-alpha has been demonstrated to modulate angiogenesis, possibly via the inhibition of endothelial cell proliferation, in vivo. The effect of TNF-alpha blockage on the ischemic limb, however, has yet to be fully elucidated. In this study we exam...
中町 智哉, 塩田 清二
Journal of The Showa Medical Association   71(5) 447-452   Oct 2011
YOFU Sachiko, OGAWA Tetsuo, NAKAMACHI Tomoya, SATOH Kazue, SHIMIZU Ai, MATSUNAGA Masaji, SHIODA Seiji
日本臨床生理学会雑誌 = Japanese journal of applied physiology   40(3) 137-143   Jun 2010
Min Li, Tomoya Nakamachi, Akira Arimura
Handbook of Biologically Active Peptides   673-681   Dec 2006
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are members of a superfamily of structurally related peptide hormones that include glucagon, glucagon-like peptide, secretin, and growth hormone-rel...

Books etc

 
Reglodi D, and Tamas A (eds.) “Pituitary Adenylate Cyclase Activating Polypeptide — PACAP”
Tomoya Nakamachi (Part:Contributor, Chapter 27. “Role of PACAP in Astrocytes and Astrocytic Tumors”)
Springer International Publishing   2016   
Takei Y, Ando H, and Tsutsui K (eds.) “Handbook of hormones: Comparative endocrinology for basic and clinical research (1st Edition)”
Tomoya Nakamachi (Part:Contributor, Chapter 10B. “Orexin” Chapter 18A. “Secretin” Chapter 18C. “Pituitary adenylate cyclase-activating polypeptide“ Chapter 18D. “Pituitary adenylate cyclase-activating polypeptide-related peptide“)
Academic Press   2015   
Kastin AJ (eds.) “Handbook of biologically active peptides (Second Edition)”
Tomoya Nakamachi (Part:Contributor, PACAP)
Academic Press   2013   
Shioda S, Homma I, Kato N (eds.) “Transmitters and Modulators in Health and Disease”
Tomoya Nakamachi (Part:Contributor, Activation of microglia induced leaning and memory deficits, Increased behavioral activity with regular circadian rhythm in PACAP specific receptor (PAC1R) transgenic mice, Expression and localization of pituitary adenylate cyclase-activating polypeptide)
Springer-Verlag   2009   
Kusano M, Shioda S (eds.) “New Frontiers in regenerative Medicine”
Tomoya Nakamachi (Part:Contributor, Does PACAP have therapeutic potential in the field of neuroregenerative medicine?, The surgical procedures of hippocampal ischemia models for the study of regeneration in rats.)
Springer-Verlag   2007   

Conference Activities & Talks

 
PACAP PLAYS AN ESSENTIAL ROLE FOR NEUROGENESIS AND NERVE REGENERATION AFTER BRAIN ISCHEMIA AND SPINAL CORD INJURY
Seiji Shioda, Takahiro Hirabayashi, Fumiko Takenoya, Nobuhiro Wada, Nobuko Tokuda, Tomoya Nakamachi
13th International Symposium on VIP, PACAP and Related Peptides   9 Dec 2017   
PACAP STIMULATES TEAR AND SALIVA SECRETION VIA DIFFERENT PACAP RECEPTORS
Nakamachi T, Shioda S.
13th International Symposium on VIP, PACAP and Related Peptides   3 Dec 2017   
Involvement of somatolactin-a and -b in regulation of pigmentation in goldfish
Kazuki Minami, Akiyoshi Hamaguchi, Makito Kobayashi, Tomoya Nakamachi, Norifumi Konno, Kouhei Matsuda
International Symposium on pituitary gland and Related Systems   1 Sep 2016   
PACAP as a tear stimulator [Invited]
Nakamachi T
Toyama University International Symposium   20 Jul 2016   
PACAP stimulates the corneal healing in mice
Nakamachi T, Seki T, Ohtaki H, Watanabe J, Hashimoto H, Shintani N, Farkas J, Reglodi D, Shioda S.
RegPep 2016   11 Jul 2016   

Social Contribution

 
The 2nd Tenure Track System International Symposium
[Planner]  University of Toyama  Recent Update in Research on the Brain and Behavior  4 Mar 2015