2016年9月
Pleiotropic and retinoprotective functions of PACAP
ANATOMICAL SCIENCE INTERNATIONAL
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- 巻
- 91
- 号
- 4
- 開始ページ
- 313
- 終了ページ
- 324
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1007/s12565-016-0351-0
- 出版者・発行元
- SPRINGER
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 27- or 38-amino acid neuropeptide, which belongs to the vasoactive intestinal polypeptide/glucagon/secretin family. PACAP and its three receptor subtypes are expressed in neural tissues of the eye, including the retina, cornea and lacrimal gland, and PACAP is known to exert pleiotropic effects throughout the central nervous system. This review provides an overview of current knowledge regarding the cell protective effects, mechanisms of action and therapeutic potential of PACAP in response to several types of eye injury.
- リンク情報
- ID情報
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- DOI : 10.1007/s12565-016-0351-0
- ISSN : 1447-6959
- eISSN : 1447-073X
- PubMed ID : 27324639
- Web of Science ID : WOS:000380690300002