2021年1月5日
Regioselective 1,3-Dipolar Cycloaddition of Nitriles with Nitrile Imines Generated from Tetrazoles
Chemistry Letters
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- 巻
- 50
- 号
- 1
- 開始ページ
- 131
- 終了ページ
- 135
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1246/cl.200634
- 出版者・発行元
- The Chemical Society of Japan
A synthesis of 3,5-disubstituted-1,2,4-triazoles from nitriles and 5-aryltetrazoles is reported. When 5-aryltetrazoles are triflylated in the presence of nitriles, the resulting 5-aryl-2-triflyltetrazoles thermally generate N-triflyl-nitrile imines through a sequence of ring-chain tautomerization and denitrogenation. The N-triflyl-nitrile imines immediately undergo 1,3dipolar cycloaddition with nitriles in a regioselective manner, forming the corresponding 1,2,4-triazoles.
- リンク情報
- ID情報
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- DOI : 10.1246/cl.200634
- ISSN : 0366-7022
- ISSN : 1348-0715
- eISSN : 1348-0715
- ORCIDのPut Code : 99486906
- Web of Science ID : WOS:000608064300006