論文

2021年3月26日

The Utility of Glasgow Prognostic Score and Palliative Prognostic Index in Patients With Head and Neck Squamous Cell Carcinoma Under Palliative Care

Ear, Nose & Throat Journal
  • Takehito Kishino
  • ,
  • Terushige Mori
  • ,
  • Takenori Miyashita
  • ,
  • Yohei Ouchi
  • ,
  • Yasushi Samukawa
  • ,
  • Takashi Fukumura
  • ,
  • Satoshi Takahashi
  • ,
  • Nobuya Monden
  • ,
  • Naoki Akisada
  • ,
  • Yuji Hayashi
  • ,
  • Masataka Nakamura
  • ,
  • Hiroshi Hoshikawa

開始ページ
014556132110051
終了ページ
014556132110051
記述言語
掲載種別
研究論文(学術雑誌)
DOI
10.1177/01455613211005114
出版者・発行元
SAGE Publications

Objectives: Palliative care patients with head and neck squamous cell carcinoma (HNSCC) often experience dysphagia and airway trouble; thus, each patient requires a specific palliative care plan based on their prognostication. However, no established specific prognostic tool performed on the day of starting end-of-life care is available for such patients. We assessed the accuracy of Glasgow prognostic score (GPS) and palliative prognostic index (PPI) and their combination to establish a specified prognostic tool for patients with HNSCC in end-of-life setting.

Methods: A retrospective clinical chart review was undertaken on patients with HNSCC in end-of life setting who were decided in Kagawa University Hospital and National Hospital Organization Shikoku Cancer Center between April 2011 and March 2019. The patients were divided into 2 categories according to GPS (0-1 and 2) and PPI (groups A-B and C). These were combined into 4 categories (PPI group A-B and GPS score 0-1: good; PPI group A-B and GPS score 2: intermediate; PPI group C and GPS score 2: poor; and PPI group C and GPS score 0-1: others). The survival curves were compared for the former 3 categories.

Results: The median survival of the scores 0-1 and 2 on GPS were 114 (72-148) and 39 (25-52) days, respectively (P < .01). These of groups A-B and C on PPI were 79 (64-99) and 16 (9-29) days, respectively (P < .01). The median survival of the good, intermediate, and poor categories was 127 (73-149), 64 (44-80), and 15 (9-27) days, respectively (P < .01 among all categories).

Conclusions: In this study, the survival of terminally ill patients with HNSCC can be predicted by the GPS, PPI, and their combination with sufficient probability.

Keywords: Glasgow prognostic score; head and neck cancer; palliative care; palliative prognostic index; terminal care.

リンク情報
DOI
https://doi.org/10.1177/01455613211005114
URL
http://journals.sagepub.com/doi/pdf/10.1177/01455613211005114
URL
http://journals.sagepub.com/doi/full-xml/10.1177/01455613211005114
ID情報
  • DOI : 10.1177/01455613211005114
  • ISSN : 0145-5613
  • eISSN : 1942-7522

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