2016年1月
Immunoglobulin G4-related disease presenting as bilateral ovarian masses and mimicking advanced ovarian cancer
JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
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- 巻
- 42
- 号
- 1
- 開始ページ
- 103
- 終了ページ
- 108
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1111/jog.12835
- 出版者・発行元
- WILEY-BLACKWELL
Immunoglobulin G4-related disease (IgG4-RD) is characterized by extensive infiltration of IgG4(+) plasma cells and fibrosis in various organs. However, the involvement of the ovary in IgG4-RD has never been reported. A 59-year-old woman presented with urinary retention. Magnetic resonance imaging and computed tomography revealed a huge multinodular pelvic mass and common iliac/para-aortic lymph node swelling. A laparotomy was performed under the suspicion of advanced ovarian cancer, and the pelvic mass was identified as ovary in origin. Histopathology of the excised tumor revealed massive lymphoplasmacytic infiltration (>90% were IgG4(+) plasma cells), storiform fibrosis, and obliterative phlebitis; thus leading to a diagnosis of IgG4-RD. We conclude that IgG4-RD can present as a bilateral ovarian mass along with lymphadenopathy, therefore mimicking ovarian cancer.
- リンク情報
- ID情報
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- DOI : 10.1111/jog.12835
- ISSN : 1341-8076
- eISSN : 1447-0756
- PubMed ID : 26461453
- Web of Science ID : WOS:000368021300015