論文

査読有り
2017年11月

Association of zinc and copper with clinical parameters in the preterm newborn

PEDIATRICS INTERNATIONAL
  • Chiharu Kojima
  • ,
  • Hiromichi Shoji
  • ,
  • Naho Ikeda
  • ,
  • Tomohiro Kitamura
  • ,
  • Ken Hisata
  • ,
  • Toshiaki Shimizu

59
11
開始ページ
1165
終了ページ
1168
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1111/ped.13409
出版者・発行元
WILEY

BackgroundGiven that preterm infants are born at a time of rapid fetal growth, they are at risk of deficiency of essential nutrients for brain development, including zinc (Zn) and copper (Cu). This study evaluate the relationship between serum Cu or Zn, gestational age (GA) and anthropometric parameters at birth in preterm infants.
MethodsThis was a retrospective study of infants <35weeks' GA from January 2010 to August 2012. We collected the data from medical records of 59 preterm infants at birth with regard to GA, anthropometric parameters, and serum Cu and Zn levels. Correlation of Cu, Zn, and GA with anthropometric parameters at birth was then done.
ResultsZn was inversely correlated with GA, bodyweight (BW), body length (BL), and head circumference (HC), and Cu was inversely correlated with the standard deviation (SD) score for BW, BL, and HC. On stepwise multiple regression analysis, GA was a significant independent predictor of Zn level, and HC SD score was a significant independent predictor of Cu level.
ConclusionsPrematurity influences Zn, and intrauterine head growth restriction influences Cu at birth in preterm infants. Further research is needed to evaluate the relationship between intrauterine growth restriction and brain Cu metabolism.

Web of Science ® 被引用回数 : 5

リンク情報
DOI
https://doi.org/10.1111/ped.13409
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000416415400005&DestApp=WOS_CPL

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