論文

査読有り 国際誌
2020年1月7日

Walking Speed: Japanese Data in Chronic Liver Diseases.

Journal of clinical medicine
  • Hiroki Nishikawa
  • Hirayuki Enomoto
  • Kazunori Yoh
  • Yoshinori Iwata
  • Yoshiyuki Sakai
  • Kyohei Kishino
  • Naoto Ikeda
  • Tomoyuki Takashima
  • Nobuhiro Aizawa
  • Ryo Takata
  • Kunihiro Hasegawa
  • Noriko Ishii
  • Yukihisa Yuri
  • Takashi Nishimura
  • Hiroko Iijima
  • Shuhei Nishiguchi
  • 全て表示

9
1
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.3390/jcm9010166

We aim to clarify the impact of walking speed (WS) and analyze factors linked to WS decline in patients with chronic liver diseases (CLDs, 165 males and 191 females, 137 liver cirrhosis patients). The WS decline is defined as <0.8 m/second (m/s), referring to the guidelines. The median (range) WS was 1.3 m/s (0.2-2.02 m/s). There were 17 patients with WS <0.8 m/s (4.8%). The WS value was significantly correlated with the handgrip strength value both in males (r2 = 0.252, p < 0.0001) and females (r2 = 0.256, p < 0.0001). In the multivariate analysis of factors associated with WS decline, only the extracellular water (ECW) to total body water (TBW) ratio using bioimpedance analysis was an independent predictor (p = 0.0398). Extracellular fluid excess was categorized as follows: normal condition (ECW to TBW ratio <0.390), mild overhydrated condition (ECW to TBW ratio 0.390-0.399), and moderate to severe overhydrated condition (ECW to TBW ratio ≥0.400). The WS value was well stratified according to the ECW to TBW ratio (normal vs. mild, p = 0.0001; mild vs. moderate to severe, p < 0.0001; normal vs. moderate to severe, p < 0.0001; overall p-value <0.0001). In conclusion, the ECW to TBW ratio can be closely linked to WS decline in CLD patients.

リンク情報
DOI
https://doi.org/10.3390/jcm9010166
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31936162
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019849
ID情報
  • DOI : 10.3390/jcm9010166
  • PubMed ID : 31936162
  • PubMed Central 記事ID : PMC7019849

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