Kohtaro Goto - My portal

Profile Information

Affiliation: Researcher, The Noguchi Institute

Degree: (BLANK)(Yokohama City University)

J-GLOBAL ID: 200901020403957690
researchmap Member ID: 1000286572

Research Interests

Research Areas

Committee Memberships

2010 - 2015

幹事, グライコサイエンス若手の会

Awards

Nov, 2009

奨励賞, フルオラスケミストリーを基盤とした効率的糖鎖合成法の開発研究, 東京糖鎖研究会

後藤浩太朗

Papers

Site-specific protein PEGylation catalyzed by endo-β-N-acetylglucosaminidase

Kohtaro Goto, Masaki Kurogochi, Shou Takashima, Masako Mori, Akio Matsuda, Mamoru Mizuno

Tetrahedron Letters, 61(6) 151475-151475, Feb, 2020 Peer-reviewedLead author
Synthesis of 1,5-Anhydro-d-fructose derivatives and evaluation of their inflammasome inhibitors.

Goto K, Ideo H, Tsuchida A, Hirose Y, Maruyama I, Noma S, Shirai T, Amano J, Mizuno M, Matsuda A

Bioorganic & medicinal chemistry, 26(13) 3763-3772, Jul, 2018 Peer-reviewedLead author
Isolation of a methylated mannose-binding protein from terrestrial worm Enchytraeus japonensis

Shigeru Ogawa, Mamoru Mizuno, Mayuko Suzuki, Kohtaro Goto, Yuriko Hirose, Akio Matsuda, Takuya Saito, Suguru Oguri, Kiyoshi Furukawa

GLYCOCONJUGATE JOURNAL, 34(5) 591-601, Oct, 2017 Peer-reviewed
A recyclable heavy fluorous tag carrying an allyl alcohol pendant group: design and evaluation toward applications in synthetic carbohydrate chemistry

Kazuo Fukuda, Mami Tojino, Kohtaro Goto, Hirofumi Dohi, Yoshihiro Nishida, Mamoru Mizuno

CARBOHYDRATE RESEARCH, 407 122-130, Apr, 2015 Peer-reviewed
Preparation of acid-resistant heavy fluorous tags for recycling in synthetic systems

Kazuo Fukuda, Mami Tojino, Kohtaro Goto, Hirofumi Dohi, Yoshihiro Nishida, Mamoru Mizuno

JOURNAL OF FLUORINE CHEMISTRY, 166 52-59, Oct, 2014 Peer-reviewed
The Effect of Glycosylation on the Antibody Recognition of a MUC2 Mucin Epitope

Katalin Uray, Mamoru Mizuno, Toshiyuki Inazu, Kohtaro Goto, Ferenc Hudecz

BIOPOLYMERS, 102(5) 390-395, Sep, 2014 Peer-reviewed
耐酸性ヘビーフルオラスタグを用いた糖鎖合成

福田和男, 戸治野真美, 後藤浩太朗, 土肥博史, 西田芳弘, 水野真盛

日本化学会講演予稿集, 94th(4) 1410, Mar 12, 2014
Effective Application of Heavy Fluorous Thioglycoside for Oligosaccharide Synthesis

Kohtaro Goto, Nueramina Nuermaimaiti, Mamoru Mizuno

CHEMISTRY LETTERS, 40(7) 756-757, Jul, 2011 Peer-reviewedLead author
Glycoside Hydrolase Family 89 alpha-N-acetylglucosaminidase from Clostridium perfringens Specifically Acts on GlcNAc alpha 1,4Gal beta 1R at the Non-reducing Terminus of O-Glycans in Gastric Mucin

Masaya Fujita, Akiko Tsuchida, Akiko Hirata, Natsumi Kobayashi, Kohtaro Goto, Kenji Osumi, Yuriko Hirose, Jun Nakayama, Takashi Yamanoi, Hisashi Ashida, Mamoru Mizuno

JOURNAL OF BIOLOGICAL CHEMISTRY, 286(8) 6479-6489, Feb, 2011 Peer-reviewed
Glycoside Hydrolase Family 89 alpha-N-acetylglucosaminidase from Clostridium perfringens Specifically Acts on GlcNAc alpha 1,4Gal beta 1R at the Non-reducing Terminus of O-Glycans in Gastric Mucin

Masaya Fujita, Akiko Tsuchida, Akiko Hirata, Natsumi Kobayashi, Kohtaro Goto, Kenji Osumi, Yuriko Hirose, Jun Nakayama, Takashi Yamanoi, Hisashi Ashida, Mamoru Mizuno

JOURNAL OF BIOLOGICAL CHEMISTRY, 286(8) 6479-6489, Feb, 2011 Peer-reviewed
Practical heavy fluorous tag for carbohydrate synthesis with minimal chromatographic purification

Kohtaro Goto, Mamoru Mizuno

TETRAHEDRON LETTERS, 51(50) 6539-6541, Dec, 2010 Peer-reviewedLead author
Use of Intramolecular Reactions in Glycosidic Bond Formation

Kohtaro Goto

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY, 22(126-28) 207-208, Jul, 2010
Multi-step Synthesis of a Protected Monosaccharide Unit by Iterative Reactions in Microreactors and Fluorous Liquid-phase Extractions

Hiroko Kawakami, Kohtaro Goto, Mamoru Mizuno

CHEMISTRY LETTERS, 38(9) 906-907, Sep, 2009 Peer-reviewed
p-Alkoxyphenyl-type heavy fluorous tag for the preparation of carbohydrate units

Mamoru Mizuno, Shunsuke Kitazawa, Kohtaro Goto

JOURNAL OF FLUORINE CHEMISTRY, 129(10) 955-960, Oct, 2008 Peer-reviewed
Substrate specificity of alpha-N-acetylglucosaminidase from intestinal bacteria

Fujita Masaya, Tsuchida Akiko, Kobayashi Natsumi, Goto Kohtaro, Osumi Kenji, Mizuno Mamoru, Yamanoi Takashi, Ashida Hisashi, Haneda Katsuji, Nakayama jun

Journal of Applied Glycoscience Supplement, 2008 6-6, 2008
Synthesis of monosaccharide units using fluorous method

Goto, K, Mizuno, M

Tetrahedron Lett., 48 5605-5608, 2007 Peer-reviewedLead author
Synthesis of aminoglycoside derivatives on a Cbz-type heavy fluorous tag

Mamoru Mizuno, Hiroharu Matsumoto, Kohtaro Goto, Keita Hamasaki

TETRAHEDRON LETTERS, 47(50) 8831-8835, Dec, 2006 Peer-reviewed
Rapid oligosaccharide and peptide syntheses on a recyclable fluorous support

Mamoru Mizuno, Kohtaro Goto, Tsuyoshi Miura, Toshiyuki Inazu

QSAR & COMBINATORIAL SCIENCE, 25(8-9) 742-752, Sep, 2006 Peer-reviewed
Synthesis of peptides and oligosaccharides by using a recyclable fluorous tag

K Goto, T Miura, M Mizuno

TETRAHEDRON LETTERS, 46(48) 8293-8297, Nov, 2005 Peer-reviewedLead author
Fluorescence modification of Gb3 oligosaccharide and rapid synthesis of oligosaccharide moieties using fluorous protective group

T Miura, S Tsujino, A Satoh, K Goto, M Mizuno, M Noguchi, T Kajimoto, M Node, Y Murakami, N Imai, T Inazu

TETRAHEDRON, 61(27) 6518-6526, Jul, 2005 Peer-reviewed

Misc.

アリル型ヘビーフルオラスタグの合成と応用

福田和男, 戸治野真美, 後藤浩太朗, 土肥博史, 西田芳弘, 水野真盛

日本化学会講演予稿集, 95th(4) 1156, Mar 11, 2015
炭素‐炭素結合型ヘビーフルオラスタグを利用した糖鎖合成

福田和男, 戸治野真美, 後藤浩太朗, 土肥博史, 西田芳弘, 水野真盛

日本糖質学会年会要旨集, 33rd 102, Jul 23, 2014
耐酸性ヘビーフルオラスタグの開発と糖鎖合成への応用

福田和男, 戸治野真美, 後藤浩太朗, 土肥博史, 西田芳弘, 水野真盛

日本糖質学会年会要旨集, 32nd 111, Jul 25, 2013
Application of fluorous chemistry for oligosaccharide synthesis

Goto Kohtaro, Mizuno Mamoru

Trends in Glycoscience and Glycotechnology, 25(146) 203-213, 2013
フルオラスタグを用いた迅速な糖鎖合成

水野真盛, 後藤浩太朗, 三浦剛, 稲津敏行

ファルマシア, (3) 213, 2007
Synthesis of peptides by using a recyclable fluorous tag

Mamoru Mizuno, Kohtaro Goto, Tsuyoshi Miura

Peptide Science 2005: Proceedings of the 42nd Japanese Peptide Symposium, 119, 2006
Synthesis of Fluorous Glycopeptide on Fluorous Support

Mizuno, M, Goto, K, Miura, T

Peptide Science 2004, 595-598, 2005
PEPTIDE SYNTHESIS ON FLUOROUS SUPPORT

M. Mizuno, K. Goto, T. Miura, T. Matsuura, T. Inazu

JOURNAL OF PEPTIDE SCIENCE, 10 146-146, 2004
A Novel Peptide Synthesis Using a Fluorous Chemistry

M. Mizuno, T. Miura, K. Goto, D. Hosaka, T. Inazu

Peptide Science 2002, 147-150, 2003
フルオラスケミストリーを基盤とした効率的糖鎖合成法の開発

後藤浩太朗, 川上宏子, 水野真盛

化学工業, 61(3) 18

Books and Other Publications

月刊ファインケミカル

後藤浩太朗 (Role: Joint author, ヘビーフルオラス法を利用した糖誘導体合成)

2011
化学工業

後藤浩太朗, 川上宏子, 水野真盛 (Role: Joint author, フルオラスケミストリーを基盤とした効率的糖鎖合成法の開発)

2010
フルオラスケミストリー

水野真盛, 後藤浩太朗, 三浦剛 (Role: Joint author, フルオラス・タグを用いた糖鎖およびペプチドの合成)

シーエムシー出版, 2005
糖鎖化学の最先端技術

稲津敏行, 後藤浩太朗 (Role: Joint author, フルオラス糖鎖合成)

シーエムシー出版, 2005

Professional Memberships

Research Projects

ENGaseを利用したDual Warhead型ADCの開発

科学研究費助成事業基盤研究(C), 日本学術振興会, Apr, 2021 - Mar, 2024

後藤浩太朗
GlycoPEGylationによる簡便な糖タンパク質合成手法の開発

科研費若手B, JST, Apr, 2014 - Mar, 2016

後藤浩太朗
One-Potフルオラス合成法を用いた糖鎖ライブラリーの構築

科研費若手B, JST, Apr, 2012 - Mar, 2014

後藤浩太朗