2017年7月
Continuous membrane potential fluctuations in motor cortex and striatum neurons during voluntary forelimb movements and pauses
NEUROSCIENCE RESEARCH
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- 巻
- 120
- 号
- 開始ページ
- 53
- 終了ページ
- 59
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.neures.2017.03.002
- 出版者・発行元
- ELSEVIER IRELAND LTD
Theoretical simulations suggest that spike rate is regulated by varying both membrane potential and its fluctuation. We investigated whether membrane potential fluctuation functionally changes in motor cortex and striatum neurons during discrete forelimb movements and pauses, or at rest, using whole-cell recording in task-performing rats. Membrane potential fluctuation was diminished by task performance, but maintained overall in the alpha/beta and gamma bands during forelimb movements and pauses. By contrast, membrane potential itself was correlated with spike rate in task-related neurons. Thus, membrane potential, but not its fluctuation, is a critical determinant of execution and pausing of discrete movements. (C) 2017 Elsevier Ireland Ltd and Japan Neuroscience Society. All rights reserved.
- リンク情報
- ID情報
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- DOI : 10.1016/j.neures.2017.03.002
- ISSN : 0168-0102
- eISSN : 1872-8111
- PubMed ID : 28267578
- Web of Science ID : WOS:000405058300007