2016年9月
Coordinated process of polarized growth in filamentous fungi.
Bioscience, biotechnology, and biochemistry
- 巻
- 80
- 号
- 9
- 開始ページ
- 1693
- 終了ページ
- 9
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1080/09168451.2016.1179092
- 出版者・発行元
- TAYLOR & FRANCIS LTD
Filamentous fungi are extremely polarized organisms, exhibiting continuous growth at their hyphal tips. The hyphal form is related to their pathogenicity in animals and plants, and their high secretion ability for biotechnology. Polarized growth requires a sequential supply of proteins and lipids to the hyphal tip. This transport is managed by vesicle trafficking via the actin and microtubule cytoskeleton. Therefore, the arrangement of the cytoskeleton is a crucial step to establish and maintain the cell polarity. This review summarizes recent findings unraveling the mechanism of polarized growth with special emphasis on the role of actin and microtubule cytoskeleton and polarity marker proteins. Rapid insertions of membranes via highly active exocytosis at hyphal tips could quickly dilute the accumulated polarity marker proteins. Recent findings by a super-resolution microscopy indicate that filamentous fungal cells maintain their polarity at the tips by repeating transient assembly and disassembly of polarity sites.
- リンク情報
- ID情報
-
- DOI : 10.1080/09168451.2016.1179092
- ISSN : 0916-8451
- eISSN : 1347-6947
- PubMed ID : 27121747
- Web of Science ID : WOS:000382588300003