People with stressful situations tend to experience lower psychological well-being highlighting the importance of involvement in activities or strategies that have the potential to promote recovery after stressful work situations. This study aimed to validate the Nepalese version of the Recovery Experience Questionnaire (REQ-N), which evaluates how individuals unwind and recuperate from work in their leisure time. Registered nurses of three university hospitals (N = 438) in Nepal were asked to complete the REQ-N voluntarily and the data was analyzed using SPSS-20 and AMOS. Reliability was examined by using the Cronbach alpha coefficient. Factorial validity was examined by using exploratory and confirmatory factor analysis. Convergent validity was examined by examining the relationships with psychological distress, overall health, happiness, job performance and job satisfaction. Cronbach's alpha coefficients for four subscales ranged from 0.67 to 0.70. A hypothesized four-factor model fitted better to the data. As expected, mastery and control subscales correlated with psychological distress, overall health, happiness, job performance, and job satisfaction. However, psychological detachment subscale correlated with poor health and relaxation subscale correlated with low job satisfaction. The REQ-N displayed an acceptable level of internal-consistency reliability. The theory-based four-factor structure and the association with psychological distress, overall health, happiness, job performance and job satisfaction for mastery and control experience subscales supported the construct validity (including factor-based validity). However, some of the model fit statistics could not meet the minimum recommendations suggesting a need of a large study involving a heterogeneous population. Also, unexpected findings for psychological detachment and relaxation may reflect the culture and values of Nepalese people and need further research.