論文

国際誌
2017年10月

Contribution of pharmaceuticals and personal care products (PPCPs) to whole toxicity of water samples collected in effluent-dominated urban streams

Ecotoxicology and Environmental Safety
  • Ikumi Tamura
  • ,
  • Yusuke Yasuda
  • ,
  • Kei ichiro Kagota
  • ,
  • Saori Yoneda
  • ,
  • Norihide Nakada
  • ,
  • Vimal Kumar
  • ,
  • Yutaka Kameda
  • ,
  • Kumiko Kimura
  • ,
  • Norihisa Tatarazako
  • ,
  • Hiroshi Yamamoto

144
開始ページ
338
終了ページ
350
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.ecoenv.2017.06.032

© 2017 Elsevier Inc. Water samples were collected from effluent-dominated urban streams in Tokushima, Kyoto, and Saitama in Japan to roughly determine the contribution of pharmaceuticals and personal care products (PPCPs) and surfactants to whole toxicity of the water. Approximately 100 PPCPs including anionic surfactants such as linear alkylbenzene sulfonate (LAS), were chemically analyzed. Using 14 water samples, chronic or sub-chronic toxicity tests were conducted on three aquatic species, the green alga Raphidocelis subcapitata, the cladoceran Ceriodaphnia dubia, and the zebrafish Danio rerio. Bioassays for the selected individual PPCPs were conducted using the three species. Assuming the concentration addition (CA) model, the contribution of each PPCP to the whole toxicity of the riverwater was estimated based on toxicity unit (TU). The contribution of PPCPs, which primarily consists of a few antibiotic agents such as triclosan and clarithromycin, ranged from 0.9% to 69% of the whole toxicity of the water samples for algae, whereas the selected LAS congeners accounted for at most 5.3%. In contrast, the contribution of LAS ranged from 0.067% to 86% and from 0.021% to 27% of the whole toxicity for cladoceran and zebrafish, respectively, whereas that of PPCPs for these species was at most 2.1% at all sampling points. Our results suggest a limited contribution of PPCPs except for antimicrobial agents and the possible substantial contribution of LAS to toxicity in cladocerans and zebrafish.

リンク情報
DOI
https://doi.org/10.1016/j.ecoenv.2017.06.032
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/28646739
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000408520100042&DestApp=WOS_CPL
Scopus
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85021136077&origin=inward
Scopus Citedby
https://www.scopus.com/inward/citedby.uri?partnerID=HzOxMe3b&scp=85021136077&origin=inward
ID情報
  • DOI : 10.1016/j.ecoenv.2017.06.032
  • ISSN : 0147-6513
  • eISSN : 1090-2414
  • PubMed ID : 28646739
  • SCOPUS ID : 85021136077
  • Web of Science ID : WOS:000408520100042

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