小笠原定久 (Sadahisa Ogasawara) - マイポータル

基本情報

所属: 千葉大学大学院医学研究院消化器内科学講師

学位: 医学士(2004年3月千葉大学)
医学博士(2012年3月千葉大学)

研究者番号: 20749155
ORCID iD: https://orcid.org/0000-0002-6540-9064
J-GLOBAL ID: 202101018981792351
researchmap会員ID: R000024773

研究キーワード

研究分野

ライフサイエンス / 消化器内科学 / 肝臓病学

経歴

2009年4月 - 現在

千葉大学医学部附属病院, 消化器内科
2007年10月 - 2009年3月

国保君津中央病院
2006年10月 - 2007年9月

千葉県立循環器病センター
2006年4月 - 2006年9月

千葉大学医学部附属病院
2005年4月 - 2006年3月

国保君津中央病院, 初期研修医
2004年4月 - 2005年3月

千葉大学医学部附属病院, 初期研修医

学歴

2008年4月 - 2012年3月

千葉大学, 大学院医学研究院
1998年4月 - 2004年3月

千葉大学, 医学部

受賞

2022年3月

Gilead’s Research Scholars Program Liver Disease Awards, Gilead Sience
2019年11月

若手奨励賞, JDDW 2019
2018年10月

The Best Presenter Award in International Session, JDDW 2018

論文

135

Randomized phase II study comparing two doses of regorafenib in second-line treatment for advanced hepatocellular carcinoma

Keisuke Koroki, Sadahisa Ogasawara, Sae Yumita, Miyuki Nakagawa, Hiroaki Kanzaki, Kazufumi Kobayashi, Masanori Inoue, Masato Nakamura, Naoya Kanogawa, Takayuki Kondo …

JHEP REPORTS 7(10) 2025年10月査読有り責任著者
Primary Analysis of a Phase II Study of Atezolizumab plus Bevacizumab for TACE-Unsuitable Patients with Tumor Burden beyond Up-To-Seven Criteria in Intermediate-Stage Hepatocellular Carcinoma: REPLACEMENT Study

Masatoshi Kudo, Kazuomi Ueshima, Kaoru Tsuchiya, Tatsuya Yamashita, Shigeo Shimose, Kazushi Numata, Yuzo Kodama, Shinji Itoh, Yasuhito Tanaka, Hidekatsu Kuroda …

LIVER CANCER 2025年6月19日査読有り
Comprehensive Analysis of Radiologic Cancer-Free Status through Various Treatment Approaches in Advanced-Stage Hepatocellular Carcinoma

Keisuke Koroki, Sadahisa Ogasawara, Ryo Izai, Takuya Yonemoto, Teppei Akatsuka, Chihiro Miwa, Sae Yumita, Masanori Inoue, Kazufumi Kobayashi, Soichiro Kiyono …

LIVER CANCER 14(3) 286-301 2025年6月査読有り
Evaluating two rechallenge strategies of immune checkpoint inhibitors: Durvalumab plus tremelimumab in advanced hepatocellular carcinoma

Takuya Yonemoto, Sadahisa Ogasawara, Naoya Kanogawa, Chihiro Miwa, Makoto Fujiya, Takahiro Tsuchiya, Midori Sawada, Teppei Akatsuka, Ryo Izai, Sae Yumita …

HEPATOLOGY RESEARCH 55(5) 718-729 2025年5月査読有り責任著者
MEGF6 knockdown ameliorates lenvatinib-induced muscle differentiation suppression and enhances the antitumor effect of lenvatinib on hepatocellular carcinoma

Na Qiang, Junjie Ao, Masato Nakamura, Keichi Katayama, Jiaqi Zhang, Tadayoshi Kogure, Keita Ogawa, Hiroaki Kanzaki, Ryuta Kojima, Keisuke Koroki …

BIOCHEMICAL PHARMACOLOGY 235 2025年5月査読有り
Protocol of the IMPACT study: randomized, multicenter, phase 3 study evaluating the efficacy of immunotherapy (Atezolizumab) plus anti-VEGF therapy (Bevacizumab) in combination with transcatheter arterial chemoembolization for unresectable hepatocellular carcinoma.

Yoshihisa Kodama, Kazuomi Ueshima, Michihisa Moriguchi, Yoshitaka Inaba, Tatsuya Yamashita, Hideki Iwamoto, Makoto Ueno, Sadahisa Ogasawara, Teiji Kuzuya, Takahiro Kodama …

BMC cancer 25(1) 434-434 2025年3月11日査読有り
Durvalumab Monotherapy in Complex Advanced Hepatocellular Carcinoma: A Real-World Study of Patients Ineligible for Combination Immunotherapy

Chihiro Miwa, Sadahisa Ogasawara, Takuya Yonemoto, Sae Yumita, Tomomi Okubo, Miyuki Nakagawa, Keisuke Koroki, Masanori Inoue, Naoya Kanogawa, Masato Nakamura …

CANCER MEDICINE 14(5) 2025年3月査読有り責任著者
Transarterial chemoembolisation combined with lenvatinib plus pembrolizumab versus dual placebo for unresectable, non-metastatic hepatocellular carcinoma (LEAP-012) : a multicentre, randomised, double-blind, phase 3 study

Masatoshi Kudo, Zhenggang Ren, Yabing Guo, Guohong Han, Hailan Lin, Jinfang Zheng, Sadahisa Ogasawara, Ji Hoon Kim, Haitao Zhao, Chuan Li …

LANCET 405(10474) 203-215 2025年1月18日査読有り
APASL clinical practice guidelines on systemic therapy for hepatocellular carcinoma-2024.

George Lau, Shuntaro Obi, Jian Zhou, Ryosuke Tateishi, Shukui Qin, Haitao Zhao, Motoyuki Otsuka, Sadahisa Ogasawara, Jacob George, Pierce K H Chow …

Hepatology international 2024年11月21日査読有り
Dual effects of targeting neuropilin-1 in lenvatinib-resistant hepatocellular carcinoma: inhibition of tumor growth and angiogenesis.

Junjie Ao, Na Qiang, Hiroaki Kanzaki, Masato Nakamura, Risa Kakiuchi, Jiaqi Zhang, Ryuta Kojima, Keisuke Koroki, Masanori Inoue, Naoya Kanogawa …

American journal of physiology. Cell physiology 327(4) C1150-C1161 2024年10月1日査読有り
A Comparison of the Effects of Alcohol Abstinence and Drinking Habit on the Survival of Patients with Alcohol-related Cirrhosis: A Retrospective Observational Study.

Hidehiro Kamezaki, Terunao Iwanaga, Takahiro Maeda, Junichi Senoo, Sadahisa Ogasawara, Naoya Kato

Internal medicine (Tokyo, Japan) 2024年7月18日査読有り
Cytokine release syndrome following durvalumab and tremelimumab in advanced hepatocellular carcinoma: A case report with cytokine and damage-associated molecular pattern analysis.

Tomomi Ozaki, Sae Yumita, Sadahisa Ogasawara, Makoto Fujiya, Takahiro Tsuchiya, Ryohei Yoshino, Midori Sawada, Teppei Akatsuka, Ryo Izai, Chihiro Miwa …

Hepatology research : the official journal of the Japan Society of Hepatology 2024年6月29日責任著者
Ramucirumab for advanced hepatocellular carcinoma in the current real world: a Japanese single-arm study post-REACH-2 (The R-evolution study).

Kazufumi Kobayashi, Sadahisa Ogasawara, Ei Itobayashi, Tomomi Okubo, Norio Itokawa, Kazuyoshi Nakamura, Michihisa Moriguchi, Shunji Watanabe, Masafumi Ikeda, Hidekatsu Kuroda …

Investigational new drugs 2024年6月6日査読有り責任著者
Clinical risk factors for portal hypertension-related complications in systemic therapy for hepatocellular carcinoma.

Kisako Fujiwara, Takayuki Kondo, Kentaro Fujimoto, Sae Yumita, Keita Ogawa, Takamasa Ishino, Miyuki Nakagawa, Terunao Iwanaga, Satoshi Tsuchiya, Keisuke Koroki …

Journal of gastroenterology 59(6) 515-525 2024年6月
Relationship between hand-foot skin reaction and external force on patients with hepatocellular carcinoma: A cohort study

Yukie Tahara, Ayumi Amemiya, Ryutaro Kase, Yuka Kitagawa, Sadahisa Ogasawara, Naoya Kato, Masatoshi Komiyama

European Journal of Oncology Nursing 70 102576-102576 2024年6月査読有り
Assessment of Macrovascular Invasion in Advanced Hepatocellular Carcinoma: Clinical Implications and Treatment Outcomes with Systemic Therapy

Masanori Inoue, Sadahisa Ogasawara, Kazufumi Kobayashi, Tomomi Okubo, Norio Itokawa, Masamichi Obu, Kentaro Fujimoto, Hidemi Unozawa, Sae Yumita, Kisako Fujiwara …

Liver Cancer 2024年5月21日査読有り責任著者
Efficacy and safety of biosimilar infliximab in bio-naïve patients with Crohn's disease.

Tsubasa Oike, Naoki Akizue, Yuki Ohta, Hirotaka Koseki, Masaya Saito, Yuya Yokoyama, Yushi Imai, Takashi Taida, Kenichiro Okimoto, Keiko Saito …

Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology 2024年5月6日査読有り
Multicenter Phase II Trial of Lenvatinib plus Hepatic Intra-Arterial Infusion Chemotherapy with Cisplatin for Advanced Hepatocellular Carcinoma: LEOPARD.

Masafumi Ikeda, Tatsuya Yamashita, Sadahisa Ogasawara, Masatoshi Kudo, Yoshitaka Inaba, Manabu Morimoto, Kaoru Tsuchiya, Satoshi Shimizu, Yasushi Kojima, Atsushi Hiraoka …

Liver cancer 13(2) 193-202 2024年4月査読有り
Risk factors of unintentional piecemeal resection in endoscopic mucosal resection for colorectal polyps ≥ 10 mm.

Tsubasa Ishikawa, Kenichiro Okimoto, Tomoaki Matsumura, Sadahisa Ogasawara, Yoshihiro Fukuda, Yoshio Kitsukawa, Yuya Yokoyama, Kengo Kanayama, Naoki Akizue, Yotaro Iino …

Scientific reports 14(1) 493-493 2024年1月4日査読有り
Use of disposable endoscope for variceal sclerotherapy.

Kisako Fujiwara, Takayuki Kondo, Kentaro Fujimoto, Mai Fujie, Naoya Kanogawa, Sadahisa Ogasawara, Naoya Kato

Endoscopy 55(S 01) E1248-E1249 2023年12月査読有り