論文

査読有り
2018年6月1日

Copper-Catalyzed Enantioselective Coupling between Allyl-boronates and Phosphates Using a Phenol-Carbene Chiral Ligand: Asymmetric Synthesis of Chiral Branched 1,5-Dienes

Synthesis (Germany)
  • Yuto Yasuda
  • ,
  • Hirohisa Ohmiya
  • ,
  • Masaya Sawamura

50
11
開始ページ
2235
終了ページ
2246
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1055/s-0036-1591548
出版者・発行元
Georg Thieme Verlag

Details of the Cu-catalyzed enantioselective allyl-allyl coupling reaction between allylboronates and (Z)-allylic phosphates using a new chiral N -heterocyclic carbene (NHC) ligand containing a phenolic hydroxy group are presented. The copper catalysis delivers enantio-enriched chiral 1,5-dienes with a tertiary stereogenic center. Compatibility with various functional groups and the use of earth-abundant and relatively low-toxicity copper as a metal are attractive features of this protocol. The utility of the chiral phenol-NHC ligand for enantioselective copper catalysis with organoboron compounds is demonstrated and enantiodiscrimination models are discussed.

リンク情報
DOI
https://doi.org/10.1055/s-0036-1591548
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000432737800010&DestApp=WOS_CPL
ID情報
  • DOI : 10.1055/s-0036-1591548
  • ISSN : 1437-210X
  • ISSN : 0039-7881
  • SCOPUS ID : 85047729450
  • Web of Science ID : WOS:000432737800010

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