2008年11月
Cyclization of Nonterminal Alkynic beta-Keto Esters Catalyzed by Gold(I) Complex with a Semihollow, End-Capped Triethynylphosphine Ligand
ORGANIC LETTERS
- ,
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- 巻
- 10
- 号
- 21
- 開始ページ
- 5051
- 終了ページ
- 5054
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1021/ol802079r
- 出版者・発行元
- AMER CHEMICAL SOC
A cationic gold(l) complex with a semihollow-shaped trialkynylphosphine catalyzed 5-exo-dig and 6-endo-dig cyclizations of various internal alkynic beta-keto esters, showing a marked advantage over a gold(I)-PPh(3) complex with respect to the rates of the reactions and the product yields. It is proposed that the gold-bound alkynic substrate in a catalytic pocket must be somewhat folded and that such a steric effect makes the carbon-carbon bond formation entropically more favorable.
- リンク情報
- ID情報
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- DOI : 10.1021/ol802079r
- ISSN : 1523-7060
- ORCIDのPut Code : 28783543
- Web of Science ID : WOS:000260534500086