CHIKA OKIMURA

Profile Information

Affiliation: 学術研究員, 大学院創成科学研究科, 山口大学

Degree: 博士（理学）(早稲田大学)

Researcher number: 80895392
ORCID ID: https://orcid.org/0000-0002-3569-6744
J-GLOBAL ID: 202001015440125097
researchmap Member ID: R000009687

Research Interests

Research Areas

Life sciences / Biophysics /

Research History

Jul, 2020 - Present

学術研究員, 創成科学研究科（理学部）, 山口大学
Aug, 2018 - Jun, 2020

研究技術員, 理学部, 山口大学
Oct, 2009 - Jul, 2018

Yamaguchi University

Awards

Papers

Linear contraction of stress fibers generates cell body rotation

Chika Okimura, Syu Akiyama, Yukinori Nishigami, Ryota Zaitsu, Tatsunari Sakurai, Yoshiaki Iwadate

bioRxiv (preprint), Jan 7, 2023 Lead author
Leading-edge elongation by follower cell interruption in advancing epithelial cell sheets.

Chika Okimura, Misaki Iwanaga, Tatsunari Sakurai, Tasuku Ueno, Yasuteru Urano, Yoshiaki Iwadate

Proceedings of the National Academy of Sciences of the United States of America, 119(18) e2119903119, May 3, 2022 Peer-reviewedLead author
Discovery of an F-actin-binding small molecule serving as a fluorescent probe and a scaffold for functional probes.

Takeru Takagi, Tasuku Ueno, Keisuke Ikawa, Daisuke Asanuma, Yusuke Nomura, Shin-Nosuke Uno, Toru Komatsu, Mako Kamiya, Kenjiro Hanaoka, Chika Okimura, Yoshiaki Iwadate, Kenzo Hirose, Tetsuo Nagano, Kaoru Sugimura, Yasuteru Urano

Science advances, 7(47) eabg8585, Nov 19, 2021 Peer-reviewed
Comparative mapping of crawling-cell morphodynamics in deep learning-based feature space.

Daisuke Imoto, Nen Saito, Akihiko Nakajima, Gen Honda, Motohiko Ishida, Toyoko Sugita, Sayaka Ishihara, Koko Katagiri, Chika Okimura, Yoshiaki Iwadate, Satoshi Sawai

PLoS computational biology, 17(8) e1009237, Aug, 2021 Peer-reviewed
Rotation of stress fibers as a single wheel in migrating fish keratocytes.

Chika Okimura, Atsushi Taniguchi, Shigenori Nonaka, Yoshiaki Iwadate

Scientific reports, 8(1) 10615-10615, Jul 17, 2018 Peer-reviewedLead author
Sensing of substratum rigidity and directional migration by fast-crawling cells.

Chika Okimura, Yuichi Sakumura, Katsuya Shimabukuro, Yoshiaki Iwadate

Physical review. E, 97(5-1) 052401-052401, May, 2018 Peer-reviewedLead author
Directional Cell Migration in Response to Repeated Substratum Stretching

Chika Okimura, Yoshiaki Iwadate

Journal of the Physical Society of Japan, 86(10) 101002-101002, Aug, 2017 Peer-reviewedInvitedLead author
Fast-crawling cell types migrate to avoid the direction of periodic substratum stretching.

Chika Okimura, Kazuki Ueda, Yuichi Sakumura, Yoshiaki Iwadate

Cell adhesion & migration, 10(4) 331-41, Jul 3, 2016 Peer-reviewedLead author
Hybrid mechanosensing system to generate the polarity needed for migration in fish keratocytes.

Chika Okimura, Yoshiaki Iwadate

Cell adhesion & migration, 10(4) 406-18, Jul 3, 2016 Peer-reviewedLead author
Shape and Area of Keratocytes Are Related to the Distribution and Magnitude of Their Traction Forces.

Ayane Sonoda, Chika Okimura, Yoshiaki Iwadate

Cell structure and function, 41(1) 33-43, Mar 26, 2016 Peer-reviewed
The Role of Stress Fibers in the Shape Determination Mechanism of Fish Keratocytes.

Takako Nakata, Chika Okimura, Takafumi Mizuno, Yoshiaki Iwadate

Biophysical journal, 110(2) 481-492, Jan 19, 2016 Peer-reviewed
The molecular dynamics of crawling migration in microtubule-disrupted keratocytes.

Hitomi Nakashima, Chika Okimura, Yoshiaki Iwadate

Biophysics and physicobiology, 12 21-9, 2015 Peer-reviewed
Electroporation of adherent cells with low sample volumes on a microscope stage.

Harunobu Tsugiyama, Chika Okimura, Takafumi Mizuno, Yoshiaki Iwadate

The Journal of experimental biology, 216(Pt 19) 3591-8, Oct 1, 2013 Peer-reviewed
Myosin-II-mediated directional migration of Dictyostelium cells in response to cyclic stretching of substratum.

Yoshiaki Iwadate, Chika Okimura, Katsuya Sato, Yuta Nakashima, Masatsune Tsujioka, Kazuyuki Minami

Biophysical journal, 104(4) 748-58, Feb 19, 2013 Peer-reviewed

Misc.

Stress-Fiber Wheel Rotation in Keratocytes

OKIMURA Chika, TANIGUCHI Atsushi, NONAKA Shigenori, IWADATE Yoshiaki

Seibutsu Butsuri, 59(2) 94-96, 2019

Presentations

Linear contraction of stress fibers kicks the substratum for their rotation

Chika Okimura

The 60th Annual Meeting of the Biophysical Society of Japan, Sep 28, 2022, The Biophysical Society of Japan Invited
魚類表皮ケラトサイトのストレスファイバの回転に伴う核と細胞膜の運動

沖村千夏

生体運動研究合同班会議 2020
魚類表皮の遊走細胞ケラトサイトのストレスファイバ車輪の回転

沖村千夏

第57回日本生物物理学会年会, Sep 26, 2019 Invited
速いアメーバ細胞の Rigidity Sensing

沖村千夏

生体運動研究合同班会議 2019
魚類ケラトサイトのストレスファイバの車輪

沖村千夏

生体運動研究合同班会議 2018
ストレスファイバーは魚類表皮ケラトサイトの遊走で車輪の役割をする

沖村千夏

新学術領域研究「数理シグナル」第1回若手ワークショップ
繰返し基質伸展刺激による細胞遊走の人為的制御

沖村千夏

生物物理学会第8回中国四国支部大会

Teaching Experience

Jun, 2021 - Jun, 2021

生物科学特別講義Ⅰ (山口大学)

Professional Memberships

Oct, 2010 - Present

日本生物物理学会

Research Projects

アメーバ細胞の中ではたらく直動回転変換ダイナミクス

科学研究費助成事業若手研究, 日本学術振興会, Apr, 2021 - Mar, 2024

沖村千夏
２つの発振源からの波の干渉による繊毛メタクロナールウェーブ伝播方向の制御

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory), Japan Society for the Promotion of Science, Jul, 2021 - Mar, 2024

Industrial Property Rights

意匠登録第1690006号エレクトロポレーション用電極付きキュベット

山本朋彦, 岩楯好昭, 沖村千夏, 継山晴進, 二階堂正隆, 清木信行

Academic Activities

日本生物物理学会第１２回中国・四国支部大会

Planning, management, etc.

岩楯好昭（山口大学）, May 22, 2021 - May 22, 2021

Social Activities

プレゼンテーション講座

Consultant

山口県立萩高校自然科学科２年次生課題研究, Jan 12, 2022
高校出前授業

Consultant

山口県立萩高校, Jan 18, 2019
ひらめき☆ときめきサイエンス

Lecturer, Consultant

櫻井建成（山口学芸短期大学）, Aug 6, 2018

Media Coverage

山口ＴＬＯ新型細胞穿孔装置を製品化従来品より安価で高性能

宇部日報, Jun, 2020 Internet
傷口塞ぐ細胞「車輪」で高速移動

朝日新聞, 総合５面, Jul 18, 2018 Newspaper, magazine

Profile Information

Research Interests

Research Areas

Research History

Awards

Papers

Misc.

Presentations

Teaching Experience

Professional Memberships

Research Projects

Industrial Property Rights

Academic Activities

Social Activities

Media Coverage

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