シッツェルオレグ (Oleg Sitsel) - マイポータル

基本情報

所属: 沖縄科学技術大学院大学海洋構造生物学ユニット准教授

ORCID iD: https://orcid.org/0000-0002-4496-7489
J-GLOBAL ID: 202401002683717744
researchmap会員ID: R000075257

外部リンク: https://www.oist.jp/ja/research/research-units/msbu

研究分野

ライフサイエンス / 構造生物化学 / Structural biology, cryoelectron microscopy, cryoelectron tomography, marine sciences, molecular biology, biophysics, biochemistry, cell biology

経歴

2024年5月 - 現在

沖縄科学技術大学院大学, 海洋構造生物学ユニット (准教授)
2018年1月 - 2024年5月

Max Planck Institute of Molecular Physiology, Department of Structural Biochemistry, Postdoctoral researcher
2016年1月 - 2018年1月

University of Oxford, Department of Biochemistry, Postdoctoral researcher (EMBO Long-Term Fellow)
2015年9月 - 2015年12月

Aarhus University, Danish Research Institute of Translational Neuroscience (DANDRITE), Postdoctoral research assistant

学歴

2010年7月 - 2015年9月

Aarhus University, Department of Molecular Biology and Genetics, Ph.D. in Molecular Biology
2007年9月 - 2010年6月

Tallinn University of Technology, B.Sc. in Gene Technology

論文

Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases

Vinayagam D, Sitsel O, Schulte U, Constantin CE, Oosterheert W, Prumbaum D, Zolles G, Fakler B, Raunser S

Nature 2025年8月20日
Multi-state kinetics of the syringe-like injection mechanism of Tc toxins

Enrica Bordignon, Oleg Sitsel, Daniel Roderer, Daniel Prumbaum, Stefan Raunser, Min Dong, Claus A.M. Seidel, Ng'ang'a, Peter Njenga, Julian Folz, Svetlana Kucher …

Science Advances 2025年1月3日
Transition metal transporting P-type ATPases: terminal metal-binding domains serve as sensors for autoinhibitory tails.

Hu Q, Sitsel O, Viktoria Bågenholm, Grønberg C, Lyu P, Pii Svane AS, Andersen KR, Laursen NS, Meloni G, Nissen P …

The FEBS journal 2024年11月28日
Yersinia entomophaga Tc toxin is released by T10SS-dependent lysis of specialized cell subpopulations

Oleg Sitsel, Zhexin Wang, Petra Janning, Lara Kroczek, Thorsten Wagner, Stefan Raunser

Nature Microbiology 2024年1月18日
Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1

Joanne L. Parker, Takafumi Kato, Gabriel Kuteyi, Oleg Sitsel, Simon Newstead

Nature Structural & Molecular Biology 2023年11月
TomoTwin: generalized 3D localization of macromolecules in cryo-electron tomograms with structural data mining

Gavin Rice, Thorsten Wagner, Markus Stabrin, Oleg Sitsel, Daniel Prumbaum, Stefan Raunser

Nature Methods 2023年6月
Specialized pathogenic cells release Tc toxins using a type 10 secretion system

Oleg Sitsel, Zhexin Wang, Petra Janning, Lara Kroczek, Thorsten Wagner, Stefan Raunser

2023年2月22日
CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor

Ying Xu, Raghuvir Viswanatha, Oleg Sitsel, Daniel Roderer, Haifang Zhao, Christopher Ashwood, Cecilia Voelcker, Songhai Tian, Stefan Raunser, Norbert Perrimon …

Nature 2022年10月13日
Structural basis of TRPC4 regulation by calmodulin and pharmacological agents

Deivanayagabarathy Vinayagam, Dennis Quentin, Oleg Sitsel, Felipe Merino, Markus Stabrin, Oliver Hofnagel, Maolin Yu, Mark W. Ledeboer, Goran Malojcic, Stefan Raunser

eLife 9 2020年7月1日
Glycan-dependent cell adhesion mechanism of Tc toxins

Daniel Roderer, Felix Bröcker, Oleg Sitsel, Paulina Kaplonek, Franziska Leidreiter, Peter H. Seeberger, Stefan Raunser

Nature Communications 2020年6月1日
Structure of the Lifeact–F-actin complex

Alexander Belyy, Felipe Merino, Oleg Sitsel, Stefan Raunser

PLOS Biology 18(11) 2020年2月16日
Towards the application of Tc toxins as a universal protein translocation system

Daniel Roderer, Evelyn Schubert, Oleg Sitsel, Stefan Raunser

Nature Communications 2019年11月20日
SPHIRE-crYOLO is a fast and accurate fully automated particle picker for cryo-EM.

Wagner T, Merino F, Stabrin M, Moriya T, Antoni C, Apelbaum A, Hagel P, Sitsel O, Raisch T, Prumbaum D …

Communications biology 2019年6月
Big insights from tiny crystals.

Sitsel O, Raunser S

Nature chemistry 2019年2月
Membrane Anchoring and Ion-Entry Dynamics in P-type ATPase Copper Transport.

Grønberg C, Sitsel O, Lindahl E, Gourdon P, Andersson M

Biophysical journal 2016年12月
Overproduction of PIB-Type ATPases.

Liu X, Sitsel O, Wang K, Gourdon P

Methods in molecular biology (Clifton, N.J.) 2016年1月
Crystallization of P-type ATPases by the High Lipid-Detergent (HiLiDe) Method.

Sitsel O, Wang K, Liu X, Gourdon P

Methods in molecular biology (Clifton, N.J.) 2016年1月
Structure and Function of Cu(I)- and Zn(II)-ATPases.

Sitsel O, Grønberg C, Autzen HE, Wang K, Meloni G, Nissen P, Gourdon P

Biochemistry 2015年9月
Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser.

Bublitz M, Nass K, Drachmann ND, Markvardsen AJ, Gutmann MJ, Barends TR, Mattle D, Shoeman RL, Doak RB, Boutet S …

IUCrJ 2015年6月
A sulfur-based transport pathway in Cu+-ATPases.

Mattle D, Zhang L, Sitsel O, Pedersen LT, Moncelli MR, Tadini-Buoninsegni F, Gourdon P, Rees DC, Nissen P, Meloni G

EMBO reports 2015年5月

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