論文

査読有り
2014年1月

Synthesis of Anthranilic Acid Derivatives through Iron-Catalyzed Ortho Amination of Aromatic Carboxamides with N-Chloroamines

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  • Tatsuaki Matsubara
  • ,
  • Sobi Asako
  • ,
  • Laurean Ilies
  • ,
  • Eiichi Nakamura

136
2
開始ページ
646
終了ページ
649
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1021/ja412521k
出版者・発行元
AMER CHEMICAL SOC

Arenes possessing an 8-quinolinylamide group as a directing group are ortho aminated with N-chloroamines and N-benzoyloxyamines in the presence of an iron/diphosphine catalyst and an organometallic base to produce anthranilic acid derivatives in high yield. The reaction proceeds via iron-catalyzed C H activation, followed by the reaction of the resulting iron intermediate with N-chloroamine. The choice of the directing group and diphosphine ligand is crucial for obtaining the anthranilic acid derivative with high yield and product selectivity.

Web of Science ® 被引用回数 : 194

リンク情報
DOI
https://doi.org/10.1021/ja412521k
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000330018600027&DestApp=WOS_CPL
URL
http://orcid.org/0000-0003-4525-5317

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