論文

査読有り
2011年5月

Iron-Catalyzed Stereospecific Activation of Olefinic C-H Bonds with Grignard Reagent for Synthesis of Substituted Olefins

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
  • Laurean Ilies
  • ,
  • Sobi Asako
  • ,
  • Eiichi Nakamura

133
20
開始ページ
7672
終了ページ
7675
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1021/ja2017202
出版者・発行元
AMER CHEMICAL SOC

The reaction of an aryl Grignard reagent with a cyclic or acyclic olefin possessing a directing group such as pyridine or imine results in the stereospecific substitution of the olefinic C-H bond syn to the directing group. The reaction takes place smoothly and without isomerization of the product olefin in the presence of a mild oxidant (1,2-dichloro-2-methylpropane) and an aromatic cosolvent. Several lines of evidence suggest that the reaction proceeds via iron-catalyzed olefinic C H bond activation rather than an oxidative Mizoroki-Heck-type reaction.

Web of Science ® 被引用回数 : 97

リンク情報
DOI
https://doi.org/10.1021/ja2017202
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000291580400014&DestApp=WOS_CPL
URL
http://orcid.org/0000-0003-4525-5317

エクスポート
BibTeX RIS