大塚菜緒 (Nao Otsuka) - マイポータル

基本情報

所属: 国立感染症研究所細菌第二部第一室主任研究官

学位: 薬学博士(岡山大学)

J-GLOBAL ID: 201801012611793100
researchmap会員ID: B000303007

研究キーワード

論文

Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines.

Zomer A, Otsuka N, Hiramatsu Y, Kamachi K, Nishimura N, Ozaki T, Poolman J, Geurtsen J

Microbial genomics 4(5) 2018年5月査読有り
Molecular epidemiology of Bordetella pertussis in Cambodia determined by direct genotyping of clinical specimens

Takumi Moriuchi, Ork Vichit, Yong Vutthikol, Md. Shafiqul Hossain, Chham Samnang, Kohei Toda, Varja Grabovac, Yukihiro Hiramatsu, Nao Otsuka, Keigo Shibayama …

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 62 56-58 2017年9月査読有り
The length of poly(C) stretch in the Bordetella pertussis Pfim3 promoter determines the vag or vrg function of the fim3 gene

Nao Otsuka, Nicole Guiso, Valerie Bouchez

MICROBIOLOGY-SGM 163(9) 1364-1368 2017年9月査読有り
A high seroprevalence of antibodies to pertussis toxin among Japanese adults: Qualitative and quantitative analyses

Takumi Moriuchi, Nao Otsuka, Yukihiro Hiramatsu, Keigo Shibayama, Kazunari Kamachi

PLOS ONE 12(7) e0181181 2017年7月査読有り
Significant Decrease in Pertactin-Deficient Bordetella pertussis Isolates, Japan

Yukihiro Hiramatsu, Yusuke Miyaji, Nao Otsuka, Yoshichika Arakawa, Keigo Shibayama, Kazunari Kamachi

EMERGING INFECTIOUS DISEASES 23(4) 699-701 2017年4月査読有り
Evaluation of a commercial loop-mediated isothermal amplification assay for diagnosis of Bordetella pertussis infection

Kazunari Kamachi, Takumi Moriuchi, Yukihiro Hiramatsu, Nao Otsuka, Keigo Shibayama

JOURNAL OF MICROBIOLOGICAL METHODS 133 20-22 2017年2月査読有り
The proline residue at position 319 of BvgS is essential for BvgAS activation in Bordetella pertussis

Yukihiro Hiramatsu, Shuji Yoshino, Yoshiko Yamamura, Nao Otsuka, Keigo Shibayama, Mineo Watanabe, Kazunari Kamachi

PATHOGENS AND DISEASE 75(1) 2017年1月査読有り
Development of vaccines against pertussis caused by Bordetella holmesii using a mouse intranasal challenge model

Momoko Saito, Keita Odanaka, Nao Otsuka, Kazunari Kamachi, Mineo Watanabe

MICROBIOLOGY AND IMMUNOLOGY 60(9) 599-608 2016年9月査読有り
BipA Is Associated with Preventing Autoagglutination and Promoting Biofilm Formation in Bordetella holmesii

Yukihiro Hiramatsu, Momoko Saito, Nao Otsuka, Eri Suzuki, Mineo Watanabe, Keigo Shibayama, Kazunari Kamachi

PLOS ONE 11(7) e0159999 2016年7月査読有り
A Novel IgM-capture enzyme-linked immunosorbent assay using recombinant Vag8 fusion protein for the accurate and early diagnosis of Bordetella pertussis infection

Nao Otsuka, Kensei Gotoh, Naoko Nishimura, Takao Ozaki, Yukitsugu Nakamura, Kiyohito Haga, Makoto Yamazaki, Fumio Gondaira, Kenji Okada, Yusuke Miyaji …

MICROBIOLOGY AND IMMUNOLOGY 60(5) 326-333 2016年5月査読有り
Action mechanism of 6, 6'-dihydroxythiobinupharidine from Nuphar japonicum, which showed anti-MRSA and anti-VRE activities.

Okamura S, Nishiyama E, Yamazaki T, Otsuka N, Taniguchi S, Ogawa W, Hatano T, Tsuchiya T, Kuroda T

Biochimica et biophysica acta 1850(6) 1245-1252 2015年6月査読有り
Molecular epidemiology of Bordetella pertussis in the Philippines in 2012-2014

Salvacion Rosario L. Galit, Nao Otsuka, Yuki Furuse, Daryl Joy V. Almonia, Lydia T. Sombrero, Rosario Z. Capeding, Socorro P. Lupisan, Mariko Saito, Hitoshi Oshitani, Yukihiro Hiramatsu …

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 35 24-26 2015年6月査読有り
Genetic Analysis of Bordetella pertussis Isolates from the 2008-2010 Pertussis Epidemic in Japan

Yusuke Miyaji, Nao Otsuka, Hiromi Toyoizumi-Ajisaka, Keigo Shibayama, Kazunari Kamachi

PLoS ONE 8(10) e77165 2013年10月4日査読有り
Bronchitis caused by Bordetella holmesii in a child with asthma misdiagnosed as mycoplasmal infection

Chihiro Katsukawa, Chieko Kushibiki, Atsumi Nishito, Rikou Nishida, Norimitsu Kuwabara, Ryuji Kawahara, Nao Otsuka, Yusuke Miyaji, Hiromi Toyoizumi-Ajisaka, Kazunari Kamachi

JOURNAL OF INFECTION AND CHEMOTHERAPY 19(3) 534-537 2013年6月査読有り
Simple and specific detection of Bordetella holmesii by using a loop-mediated isothermal amplification assay

Nao Otsuka, Shuji Yoshino, Kimiko Kawano, Hiromi Toyoizumi-Ajisaka, Keigo Shibayama, Kazunari Kamachi

MICROBIOLOGY AND IMMUNOLOGY 56(7) 486-489 2012年7月査読有り
Transmission of Bordetella holmesii during Pertussis Outbreak, Japan

Hajime Kamiya, Nao Otsuka, Yuka Ando, Fumito Odaira, Shuji Yoshino, Kimiko Kawano, Hirokazu Takahashi, Toshihide Nishida, Yoshio Hidaka, Hiromi Toyoizumi-Ajisaka …

EMERGING INFECTIOUS DISEASES 18(7) 1166-1169 2012年7月査読有り
Prevalence and Genetic Characterization of Pertactin-Deficient Bordetella pertussis in Japan

Nao Otsuka, Hyun-Ja Han, Hiromi Toyoizumi-Ajisaka, Yukitsugu Nakamura, Yoshichika Arakawa, Keigo Shibayama, Kazunari Kamachi

PLOS ONE 7(2) e31985 2012年2月査読有り
Marked difference between adults and children in Bordetella pertussis DNA load in nasopharyngeal swabs

Y. Nakamura, K. Kamachi, H. Toyoizumi-Ajisaka, N. Otsuka, R. Saito, J. Tsuruoka, T. Katsuta, N. Nakajima, K. Okada, T. Kato …

CLINICAL MICROBIOLOGY AND INFECTION 17(3) 365-370 2011年3月査読有り
Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents

Abugafar M. L. Hossion, Nao Otsuka, Rafiya K. Kandahary, Tomofusa Tsuchiya, Wakano Ogawa, Akimasa Iwado, Yoshito Zamami, Kenji Sasaki

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 20(17) 5349-5352 2010年9月査読有り
Synergistic Effect of Kaempferol Glycosides Purified from Laurus nobilis and Fluoroquinolones on Methicillin-Resistant Staphylococcus aureus

Mei-Hua Liu, Nao Otsuka, Kumiko Noyori, Sumiko Suiota, Wakano Ogawa, Teruo Kuroda, Tsutomu Hatano, Tomofusa Tsuchiya

BIOLOGICAL & PHARMACEUTICAL BULLETIN 32(3) 489-492 2009年3月査読有り

もっとみる

所属学協会

産業財産権

特許第6198298号百日咳の血清診断方法

倉光菜緒, 蒲地一成, 柴山恵吾, 中村幸嗣, 荒川宜親, 権平文夫, 山崎誠, 羽賀清人
特許第5680535号新規フラバノン誘導体

佐々木健二, 土屋友房, アブガファー, エムディー, ロックマン, ホッション, 大塚菜緒, 座間味義人, 黒崎勇二
特開2014-202535 百日咳の血清診断方法

倉光菜緒, 蒲地一成, 柴山恵吾, 中村幸嗣, 荒川宜親, 権平文夫, 山崎誠, 羽賀清人
WO2011-013735 新規フラバノン誘導体

佐々木健二, 土屋友房, アブガファー, エムディー, ロックマン, ホッション, 大塚菜緒, 座間味義人, 黒崎勇二