論文

査読有り
2012年9月

Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria

GASTROINTESTINAL ENDOSCOPY
  • Atsushi Kanno
  • Kazuyuki Ishida
  • Shin Hamada
  • Fumiyoshi Fujishima
  • Jun Unno
  • Kiyoshi Kume
  • Kazuhiro Kikuta
  • Morihisa Hirota
  • Atsushi Masamune
  • Kennichi Satoh
  • Kenji Notohara
  • Tooru Shimosegawa
  • 全て表示

76
3
開始ページ
594
終了ページ
602
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.gie.2012.05.014
出版者・発行元
MOSBY-ELSEVIER

Background: It is controversial whether EUS-guided FNA by using 22-gauge (G) needles is useful for the diagnosis or evaluation of autoimmune pancreatitis (AIP).
Objective: To evaluate the usefulness of EUS-FNA by 22-G needles for the histopathological diagnosis of AIP.
Design: A retrospective study.
Setting: Single academic center.
Patients: A total of 273 patients, including 25 with AIP, underwent EUS-FNA and histological examinations.
Results: EUS-FNA by using 22-G needles provided adequate tissue samples for histopathological evaluation because more than 10 high-power fields were available for evaluation in 20 of 25 patients (80%). The mean immunoglobulin G4-positive plasma cell count was 13.7/high-power field. Obliterative phlebitis was observed in 10 of 25 patients (40%). In the context of the International Consensus Diagnostic Criteria for AIP, 14 and 6 of 25 patients were judged to have level 1 (positive for 3 or 4 items) and level 2 (positive for 2 items) histological findings, respectively, meaning that 20 of 25 patients were suggested to have lymphoplasmacytic sclerosing pancreatitis based on the International Consensus Diagnostic Criteria. The diagnosis in 1 patient was type 2 AIP because a granulocytic epithelial lesion was identified in this patient.
Limitations: A retrospective study with a small number of patients.
Conclusions: The results of this study suggest that EUS-FNA by using 22-G needles provides tissue samples adequate for histopathological evaluation and greatly contributes to the histological diagnosis of AIP. (Gastrointest Endosc 2012;76:594-602.)

リンク情報
DOI
https://doi.org/10.1016/j.gie.2012.05.014
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/22898417
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000307948600020&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.gie.2012.05.014
  • ISSN : 0016-5107
  • PubMed ID : 22898417
  • Web of Science ID : WOS:000307948600020

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