2021年5月1日
MR lymphography with superparamagnetic iron oxide for sentinel lymph node mapping of N0 early oral cancer: A pilot study.
Dento maxillo facial radiology
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- 巻
- 50
- 号
- 4
- 開始ページ
- 20200333
- 終了ページ
- 20200333
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1259/dmfr.20200333
- 出版者・発行元
- BRITISH INST RADIOLOGY
Objectives: The purpose of this pilot study was to evaluate the usefulness of magnetic resonance lymphography (MRL) with superparamagnetic iron oxide (SPIO) in sentinel lymph node (SLN) mapping of clinically N0 early oral cancer, and to conduct a comparative study of this MRL with CT lymphography (CTL).Methods: CTL and MRL were performed for SLN mapping before surgery for 20 patients with clinically N0 early oral cancer. The detection rate, number, and location of SLNs in CTL and MRL were evaluated. Furthermore, optimal scanning/imaging timing in MRL was examined.Results: SLNs were detected by CTL in 18 (90%) patients, and the total and mean number of SLN were 35 and 1.8, respectively. All SLNs could be detected 2 min and 3.5-5 min after contrast medium injection. In all patients, SLNs were detected by MRL at 10 min after SPIO injection, and the total and mean number of SLN was 53 and 2.7, respectively. MRL at 30 min after the injection showed additional 18 secondary lymph nodes.Conclusion: MRL with SPIO is safe and useful imaging for the detection of SLNs in clinically N0 early oral cancer, and the optimal imaging timing is 10 min after SPIO injection.
- リンク情報
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- DOI
- https://doi.org/10.1259/dmfr.20200333
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/33180632
- PubMed Central
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8077995
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000646186900004&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1259/dmfr.20200333
- ISSN : 0250-832X
- eISSN : 1476-542X
- PubMed ID : 33180632
- PubMed Central 記事ID : PMC8077995
- Web of Science ID : WOS:000646186900004