2016年2月
Intrajejunal infusion of 2-monoacylglycerol reduced food intake without inducing diarrhea in rats
JOURNAL OF PHARMACOLOGICAL SCIENCES
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- 巻
- 130
- 号
- 2
- 開始ページ
- 136
- 終了ページ
- 138
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1016/j.jphs.2016.01.004
- 出版者・発行元
- JAPANESE PHARMACOLOGICAL SOC
Some nutrients, such as carbohydrate, fat and protein, are known to stimulate satiety. However, the effect of sn-2-monoacylglycerol (2-MG), one of the digestive products of triglycerides, on food intake is still unclear. In the present study, the effects of 2-MG on food intake and diarrhea were evaluated and compared with long-chain fatty acid (LCFA) in rats by intrajejunal infusion.
Intrajejunal infusion of 2-MG reduced food intake. In addition, 2-MG did not induce diarrhea at the condition that it comparably reduced food intake as compared with LCFA. These results suggest that 2-MG stimulates satiety without inducing diarrhea, different from LCFA. (C) 2016 Japanese Pharmacological Society. Production and hosting by Elsevier B.V.
Intrajejunal infusion of 2-MG reduced food intake. In addition, 2-MG did not induce diarrhea at the condition that it comparably reduced food intake as compared with LCFA. These results suggest that 2-MG stimulates satiety without inducing diarrhea, different from LCFA. (C) 2016 Japanese Pharmacological Society. Production and hosting by Elsevier B.V.
- リンク情報
- ID情報
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- DOI : 10.1016/j.jphs.2016.01.004
- ISSN : 1347-8613
- eISSN : 1347-8648
- Web of Science ID : WOS:000374250600014