論文

査読有り 国際誌
2020年1月27日

Entomological Assessment of the Status and Risk of Mosquito-borne Arboviral Transmission in Ghana.

Viruses
  • Michael Amoa-Bosompem
  • ,
  • Daisuke Kobayashi
  • ,
  • Katsunori Murota
  • ,
  • Astri Nur Faizah
  • ,
  • Kentaro Itokawa
  • ,
  • Ryosuke Fujita
  • ,
  • Joseph Harold Nyarko Osei
  • ,
  • Esinam Agbosu
  • ,
  • Deborah Pratt
  • ,
  • Shohei Kimura
  • ,
  • Kofi Dadzie Kwofie
  • ,
  • Mitsuko Ohashi
  • ,
  • Joseph H Kofi Bonney
  • ,
  • Samuel Dadzie
  • ,
  • Toshinori Sasaki
  • ,
  • Nobuo Ohta
  • ,
  • Haruhiko Isawa
  • ,
  • Kyoko Sawabe
  • ,
  • Shiroh Iwanaga

12
2
記述言語
英語
掲載種別
DOI
10.3390/v12020147

Entomological surveillance is one of the tools used in monitoring and controlling vector-borne diseases. However, the use of entomological surveillance for arboviral infection vector control is often dependent on finding infected individuals. Although this method may suffice in highly endemic areas, it is not as effective in controlling the spread of diseases in low endemic and non-endemic areas. In this study, we examined the efficiency of using entomological markers to assess the status and risk of arbovirus infection in Ghana, which is considered a non-endemic country, by combining mosquito surveillance with virus isolation and detection. This study reports the presence of cryptic species of mosquitoes in Ghana, demonstrating the need to combine morphological identification and molecular techniques in mosquito surveillance. Furthermore, although no medically important viruses were detected, the importance of insect-specific viruses in understanding virus evolution and arbovirus transmission is discussed. This study reports the first mutualistic relationship between dengue virus and the double-stranded RNA Aedes aegypti totivirus. Finally, this study discusses the complexity of the virome of Aedes and Culex mosquitoes and its implication for arbovirus transmission.

リンク情報
DOI
https://doi.org/10.3390/v12020147
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32012771
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077231