久保田智巳 (Tomomi Kubota) - マイポータル

基本情報

所属: 独立行政法人産業技術総合研究所糖鎖医工学研究センター糖鎖遺伝子機能解析チーム

J-GLOBAL ID: 200901082033407828
researchmap会員ID: 0000006900

外部リンク: http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=T68031554

研究キーワード

タンパク質結晶学タンパク質の結晶化糖転移酵素酵素反応速度論メタノール資化性酵母

MISC

Structural Basis of Carbohydrate Transfer Activity by Human UDP-GalNAc: Polypeptide α-NAcetylgalactosaminyltransferase (pp-GalNAc-T10)

KUBOTA Tomomi, SHIBA Tomoo, SHIBA Tomoo, SUGIOKA Shigemi, FURUKAWA Sanae, SAWAKI Hiromichi, KATO Ryuich, WAKATSUKI Soichi, NARIMATSU Hisashi

JOURNAL OF MOLECULAR BIOLOGY 359(3) 708-727 2006年6月
Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells

T Iwai, T Kudo, R Kawamoto, T Kubota, A Togayachi, T Hiruma, T Okada, T Kawamoto, K Morozumi, H Narimatsu

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102(12) 4572-4577 2005年3月
Characterization of a novel human UDP-GalNAc transferase, pp-GalNAc-T15

LM Cheng, K Tachibana, H Iwasaki, A Kameyama, Y Zhang, T Kubota, T Hiruma, K Tachibana, T Kudo, JM Guo …

FEBS LETTERS 566(1-3) 17-24 2004年5月
Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N '-diacetyllactosediamine, GalNAc beta 1-4GlcNAc

T Sato, M Gotoh, K Kiyohara, A Kameyama, T Kubota, N Kikuchi, Y Ishizuka, H Iwasaki, A Togayachi, T Kudo …

JOURNAL OF BIOLOGICAL CHEMISTRY 278(48) 47534-47544 2003年11月
Assembly kinetics of bc(1) complex membrane protein investigated by using a continuous-angle laser light scattering technique

K Onuma, N Kanzaki, T Kubota

JOURNAL OF PHYSICAL CHEMISTRY B 107(40) 11224-11229 2003年10月
Lewis type 1 antigen synthase (beta 3Gal-T5) is transcriptionally regulated by homeoproteins

S Isshiki, T Kudo, S Nishihara, Y Ikehara, A Togayachi, A Furuya, K Shitara, T Kubota, M Watanabe, M Kitajima …

JOURNAL OF BIOLOGICAL CHEMISTRY 278(38) 36611-36620 2003年9月
Rationalization of membrane protein crystallization with polyethylene glycol using a simple depletion model

S Tanaka, M Ataka, K Onuma, T Kubota

BIOPHYSICAL JOURNAL 84(5) 3299-3306 2003年5月
Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine: Polypeptide N-acetylgalactosaminyltransferase 2

H Iwasaki, Y Zhang, K Tachibana, M Gotoh, N Kikuchi, YD Kwon, A Togayachi, T Kudo, T Kubota, H Narimatsu

JOURNAL OF BIOLOGICAL CHEMISTRY 278(8) 5613-5621 2003年2月
Cloning and Characterization of a New Human UDP-N-Acetyl-a-D-galactosamine: Polypeptide N-Acetylgalactosaminyltransferase, Designated pp-GalNAc-T13, that is Specifically Expressed in Neurons and Synthesizes Tn Antigen*

ZHANG Y, IWASAKI H, KALKA T B, HENNET T, HISATOMI H, NAKAJIMA K, NAKAMURA M, MARTH J D, NARIMATSU H

J BIOL CHEM 278(1) 573-584 2003年
Molecular cloning and characterization of a novel UDP-Gal : GaINAc alpha peptide beta 1,3-galactosyltransferase (ClGal-T2), an enzyme synthesizing a core 1 structure of O-glycan

T Kudo, T Iwai, T Kubota, H Iwasaki, Y Takayma, T Hiruma, N Inaba, Y Zhang, M Gotoh, A Togayachi …

JOURNAL OF BIOLOGICAL CHEMISTRY 277(49) 47724-47731 2002年12月
An insight into the pathway of the amyloid fibril formation of hen egg white lysozyme obtained from a small-angle X-ray and neutron scattering study

Y Yonezawa, S Tanaka, T Kubota, K Wakabayashi, K Yutani, S Fujiwara

JOURNAL OF MOLECULAR BIOLOGY 323(2) 237-251 2002年10月
Molecular cloning and characterization of a novel member of the UDP-GalNAc : polypeptide N-acetylgalactosaminyltransferase family, pp-GalNAc-T12

JM Guo, Y Zhang, LM Cheng, H Iwasaki, H Wang, T Kubota, K Tachibana, H Narimatsu

FEBS LETTERS 524(1-3) 211-218 2002年7月
AFM observation of the surface morphology and impurity effects on orthorhombic hen egg-white lysozyme crystals

Y Matsuzuki, T Kubota, XY Liu, M Ataka, KJ Takano

JOURNAL OF CRYSTAL GROWTH 242(1-2) 199-208 2002年7月
Dynamic light scattering investigation in aqueous solutions of bc1-complex membrane protein

Kazuo Onuma, Tomomi Kubota, Shinpei Tanaka, Noriko Kanzaki, Atsuo Ito, Kazunori Tsutsui

Journal of Physical Chemistry B 106(16) 4318-4324 2002年4月25日
The effect of amphiphilic additives on the growth and morphology of Aspergillus niger acid proteinase A crystals

S Tanaka, M Ataka, T Kubota, T Soga, K Homma, WC Lee, M Tanokura

JOURNAL OF CRYSTAL GROWTH 234(1) 247-254 2002年1月
Importance of nitrate in the crystal growth of cytochrome c from four biological species judged by morphodrom analysis

T Kubota, K Homma, J Noda, T Yamane, M Ataka

JOURNAL OF CRYSTAL GROWTH 233(4) 813-822 2001年12月

久保田智巳

基本情報

研究キーワード

MISC

所属学協会

メニュー