崎山樹 (Shigeru Sakiyama) - マイポータル - researchmap

基本情報

所属: 旧所属千葉県がんセンター研究局局長

学位: 医学博士(千葉大学大学院医学研究科)

J-GLOBAL ID: 200901036699284753
researchmap会員ID: 0000013220

研究キーワード

4

研究分野

1

ライフサイエンス / 病態医化学 /

経歴

10

1991年 - 現在

千葉県がんセンター研究局長
1991年 - 現在

Director, Chiba Cancer Center Res. Inst.
1981年 - 1991年

千葉県がんセンター研究所生化学研究部部長
1981年 - 1991年

Head, Div. Biochemistry,
1972年 - 1981年

千葉県がんセンター研究所生化学研究部主任研究員
1972年 - 1981年

Senior Research Fellow, Div. Biochemistry,
1969年 - 1972年

マサチューセッツ工科大学研究員
1969年 - 1972年

Research Associate Dept of Biology, M.I.T.
千葉県がんセンター
千葉県がんセンター

学歴

4

委員歴

5

MISC

70

Accumulation of p27(KIP1) is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines

Y Nakamura, T Ozaki, H Koseki, A Nakagawara, S Sakiyama

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 307(1) 206-213 2003年7月
Accumulation of p27(KIP1) is associated with BMP2-induced growth arrest and neuronal differentiation of human neuroblastoma-derived cell lines

Y Nakamura, T Ozaki, H Koseki, A Nakagawara, S Sakiyama

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 307(1) 206-213 2003年7月
Tada Y, O-Wang J, Wada A, Takiguchi Y, Tatsumi K, Kuriyama T, Sakiyama S, Tagawa M. Fas ligand-expressing tumors induce tumor-specific protective immunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity.

Cancer Gene Ther. 10(2) 134-140 2003年
Ugai S, Shimozato O, Kawamura K, Wang YQ, Yamaguchi T, Saisho H, Sakiyama S, Tagawa M. Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.

Cancer Gene Ther. 10(3) 187-192 2003年
Tada Y, O-Wang J, Yu L, Shimozato O, Wang YQ, Takiguchi Y, Tatsumi K, Kuriyama T, Takenaga K, Sakiyama S, Tagawa M. T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of den・・・

Cancer Gene Ther. 10(6) 451-456 2003年
Sakiyama S, Yu L, Tomizawa M, Shimada H, Kadomatsu K, Muramatsu T, Ikematsu S, Nakagawara A, Tagawa M. Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.

Adv Enzyme Regul. (43) 57-66 2003年
Oga M, Takenaga K, Sato Y, Nakajima H, Koshikawa N, Osato K, Sakiyama S. Inhibition of metastatic brain tumor growth by intramuscular administration of the endostatin gene.

Int J Oncol. 23(1) 73-79 2003年
Iwadate Y, Yamaura A, Sakiyama S, Sato Y, Tagawa M. Glioma-specific cytotoxic T cells can be effectively induced by subcutaneous vaccination of irradiated wild-type tumor cells without artificialcytokine production.

Int J Oncol. 23(2) 483-488 2003年
Yu L, Ugai S, O-Wang J, Namba M, Kadomatsu K, Muramatsu T, Matsubara S, Sakiyama S, Tagawa M. Cell growth-and p53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells.

Oncol Rep. 10(5) 1301-1305 2003年
Ohira M, Morohashi A, Inuzuka H, Shishikura E, Kawamoto T, Kageyama H, Nakamura Y, Isogai E, Takayasu H, Sakiyama S, Suzuki Y, Sugano S, Goto T, Sato S, Nakagawara A. Expression profiling and Characterization of 4200 genes cloned from primary neuroblas・・・

Oncogene. 22(35) 5525-5536 2003年
Tomizawa M, Yu L, Wada A, Tamaoki T, Kadomatsu K, Muramatsu T, Matsubara S, Watanabe K, Ebara M, Saisho H, Sakiyama S, Tagawa M. A promoter region of the midkine gene that is frequently expressed in human hepatocelluar carcinoma can activate a suicide ・・・

Br J Cancer. 89(6) 1086-1090 2003年
Ugai S, Shimozato O, Yu L, Wang YQ, Kawamura K, Yamamoto H, Yamaguchi T, Saisho H, Sakiyama S, Tagawa M. Transduction of the IL-21 and IL-23 genes in human pancreatic carcinoma cells produces natural killer cell-dependent and-independent antitumor effe・・・

Cancer Gene Ther. 10(10) 771-778 2003年
Tada Y, O-Wang J, Wada A, Takiguchi Y, Tatsumi K, Kuriyama T, Sakiyama S, Tagawa M. Fas ligand-expressing tumors induce tumor-specific protective immunity in the inoculated hosts but vaccination with the apoptotic tumors suppresses antitumor immunity.

Cancer Gene Ther. 10(2) 134-140 2003年
Ugai S, Shimozato O, Kawamura K, Wang YQ, Yamaguchi T, Saisho H, Sakiyama S, Tagawa M. Expression of the interleukin-21 gene in murine colon carcinoma cells generates systemic immunity in the inoculated hosts.

Cancer Gene Ther. 10(3) 187-192 2003年
Tada Y, O-Wang J, Yu L, Shimozato O, Wang YQ, Takiguchi Y, Tatsumi K, Kuriyama T, Takenaga K, Sakiyama S, Tagawa M. T-cell-dependent antitumor effects produced by CD40 ligand expressed on mouse lung carcinoma cells are linked with the maturation of den・・・

Cancer Gene Ther. 10(6) 451-456 2003年
Sakiyama S, Yu L, Tomizawa M, Shimada H, Kadomatsu K, Muramatsu T, Ikematsu S, Nakagawara A, Tagawa M. Utilization of the promoter region of the midkine gene as a tool to drive therapeutic genes in a tumor specific manner.

Adv Enzyme Regul. (43) 57-66 2003年
Oga M, Takenaga K, Sato Y, Nakajima H, Koshikawa N, Osato K, Sakiyama S. Inhibition of metastatic brain tumor growth by intramuscular administration of the endostatin gene.

Int J Oncol. 23(1) 73-79 2003年
Iwadate Y, Yamaura A, Sakiyama S, Sato Y, Tagawa M. Glioma-specific cytotoxic T cells can be effectively induced by subcutaneous vaccination of irradiated wild-type tumor cells without artificialcytokine production.

Int J Oncol. 23(2) 483-488 2003年
Yu L, Ugai S, O-Wang J, Namba M, Kadomatsu K, Muramatsu T, Matsubara S, Sakiyama S, Tagawa M. Cell growth-and p53-dependent transcriptional activity of the midkine promoter confers suicide gene expression in tumor cells.

Oncol Rep. 10(5) 1301-1305 2003年
Ohira M, Morohashi A, Inuzuka H, Shishikura E, Kawamoto T, Kageyama H, Nakamura Y, Isogai E, Takayasu H, Sakiyama S, Suzuki Y, Sugano S, Goto T, Sato S, Nakagawara A. Expression profiling and Characterization of 4200 genes cloned from primary neuroblas・・・

Oncogene. 22(35) 5525-5536 2003年

もっとみる

所属学協会

6

共同研究・競争的資金等の研究課題

2

腫瘍診断・治療学

科学研究費補助金 1990年
General Oncology

Grant-in-Aid for Scientific Research 1990年