山内貴靖 (Takayasu Yamauchi) - マイポータル

基本情報

所属: 星薬科大学合成化学研究室准教授

学位: 博士（薬学）

J-GLOBAL ID: 200901090429109334
researchmap会員ID: 0000014697

研究キーワード

研究分野

ライフサイエンス / 薬系化学、創薬科学 /

論文

Synthesis, In Silico Study, Antibacterial and Antifungal Activities of N-phenylbenzamides

Melanny Ika Sulistyowaty, Galih Satrio Putra, Tutuk Budiati, Anastasia Wheni Indrianingsih, Farida Anwari, Dini Kesuma, Katsuyoshi Matsunami, Takayasu Yamauchi

International Journal of Molecular Sciences 24(3) 2023年2月査読有り
Possible mechanism for improving the endogenous immune system through the blockade of peripheral μ-opioid receptors by treatment with naldemedine.

Eizoh Gondoh, Yusuke Hamada, Tomohisa Mori, Yusuke Iwazawa, Asami Shinohara, Michiko Narita, Daisuke Sato, Hiroyuki Tezuka, Takayasu Yamauchi, Mayu Tsujimura …

British journal of cancer 127(8) 1565-1574 2022年8月9日査読有り
Further investigation of the rapid-onset and short-duration action of the G protein-biased μ-ligand oliceridine

Tomohisa Mori, Yoshinori Takemura, Takamichi Arima, Yoshiyuki Iwase, Michiko Narita, Kanako Miyano, Yusuke Hamada, Yukari Suda, Akinobu Matsuzawa, Kazuyuki Sugita …

Biochemical and Biophysical Research Communications 534 988-994 2021年1月1日査読有り
Transition-Metal-Free Synthesis of Pyridine Derivatives by Thermal Cyclization of N -Propargyl Enamines

Yuya Chikayuki, Takakane Miyashige, Shiori Yonekawa, Akiko Kirita, Natsuko Matsuo, Hiroyoshi Teramoto, Shigeru Sasaki, Kimio Higashiyama, Takayasu Yamauchi

Synthesis (Germany) 52(7) 1113-1121 2020年4月査読有り最終著者責任著者
Transition metal-free cyclization of N-boc-N-propargylenamines

Yuya Chikayuki, Yasuaki Kouno, Shiori Yonekawa, Haruka Ishikawa, Yoko Waki, Hiroyoshi Teramoto, Shigeru Sasaki, Kimio Higashiyama, Takayasu Yamauchi

Heterocycles 100(5) 719-746 2020年査読有り最終著者責任著者
Substituent effects in regio- And stereoselective ring-opening reaction of aziridines with ET3N·3HF for β-fluoroamine synthesis

Shigeru Sasaki, Satono Watanabe, Kaori Shiino, Yuko Yanaka, Shiho Kaneko, Kana Miyamoto, Ayano Yasui, Hina Sakaino, Hiroyoshi Teramoto, Takayasu Yamauchi …

Heterocycles 97(2) 823-841 2018年査読有り
Usefulness for the combination of G protein- and β-arrestin-biased ligands of μ-opioid receptors: Prevention of antinociceptive tolerance

Tomohisa Mori, Naoko Kuzumaki, Takamichi Arima, Michiko Narita, Ryunosuke Tateishi, Takashige Kondo, Yusuke Hamada, Hirotsugu Kuwata, Miho Kawata, Mitsuaki Yamazaki …

Molecular Pain 13 2017年10月査読有り
Design and synthesis of a piperidinone scaffold as an analgesic through kappa-opioid receptor: Structure-activity relationship study of matrine alkaloids

Hiroyoshi Teramoto, Takayasu Yamauchi, Yasushi Terado, Sanae Odagiri, Shigeru Sasaki, Kimio Higashiyama

Chemical and Pharmaceutical Bulletin 64(5) 410-419 2016年査読有り責任著者
Development of κ opioid receptor agonists by focusing on phenyl substituents of 4-dimethylamino-3-phenylpiperidine derivatives: Structure-activity relationship study of matrine type alkaloids

Hiroyoshi Teramoto, Takayasu Yamauchi, Shigeru Sasaki, Kimio Higashiyama

Chemical and Pharmaceutical Bulletin 64(5) 420-431 2016年査読有り責任著者
Synthesis of α,α-difluoro-β-hydroxy ketone via the La(OTf)<inf>3</inf>-catalyzed aldol reaction of carbonyl compounds with difluoroenol O-Boc esters

Shigeru Sasaki, Tatuo Suzuki, Toshihiro Uchiya, Shigenobu Toyota, Akira Hirano, Mao Tanemura, Hiroyoshi Teramoto, Takayasu Yamauchi, Kimio Higashiyama

Journal of Fluorine Chemistry 192 78-85 2016年査読有り
Bisoxazoline-catalyzed asymmetric nucleophilic addition of diethyl zinc to fluorinated alkyl ketones: Enantiofacial control by changing the bisoxazoline substituent

Shigeru Sasaki, Takayasu Yamauchi, Masatomi Kanai, Akihiro Ishii, Kimio Higashiyama

Bulletin of the Chemical Society of Japan 88(1) 200-208 2015年査読有り
Effect of p-aminophenols on tyrosinase activity

Yu Komori, Masahiko Imai, Takayasu Yamauchi, Kimio Higashiyama, Noriko Takahashi

BIOORGANIC & MEDICINAL CHEMISTRY 22(15) 3994-4000 2014年8月査読有り
Total synthesis of the proposed structures of eushearilide

Takayasu Yamauchi, Jun Ichi Takidaira, Kenya Okamoto, Takaya Sugiura, Hiroki Horikoshi, Shintaro Kudo, Shigeru Sasaki, Noriko Mizushima, Kimio Higashiyama

Heterocycles 88(2) 1175-1189 2014年査読有り筆頭著者責任著者
ASYMMETRIC SYNTHESES OF PYRROLIDINE AND PIPERIDINE DERIVATIVES VIA REGIO- AND STEREO-SELECTIVE RING-OPENING REACTIONS OF CHIRAL AZIRIDINE

Kimio Higashiyama, Masataka Matsumura, Emiko Kurita, Takayasu Yamauchi

HETEROCYCLES 86(1) 371-380 2012年12月査読有り最終著者
A combination of liposomal sunitinib plus liposomal irinotecan and liposome co-loaded with two drugs enhanced antitumor activity in PC12-bearing mouse

Yoshie Maitani, Hiroshi Saito, Yuki Seishi, Yuko Iwase, Takayasu Yamauchi, Kimio Higashiyama, Takashi Sugino

JOURNAL OF DRUG TARGETING 20(10) 873-882 2012年12月査読有り
Brønsted acid catalyzed friedel-crafts alkylation reactions of trifluoromethyl-α,β-ynones with indoles

Shigeru Sasaki, Yuta Ikekame, Manabu Tanayama, Takayasu Yamauchi, Kimio Higashiyama

Synlett 23(18) 2699-2703 2012年査読有り
Erratum: Concise total synthesis of (-)-deoxocuscohygrine and (-)-dihydrocuscohygrine (The Journal of Organic Chemistry (2008) 73 (9784) DOI: 10.1021/jo801700f)

Takayasu Yamauchi, Sachi Hagiwara, Kimio Higashiyama

Journal of Organic Chemistry 76 6464 2011年8月5日
Direct aldol reaction of trifluoromethyl ketones with ketones catalyzed by Et<inf>2</inf>Zn and secondary amines

Shigeru Sasaki, Kasumi Kikuchi, Takayasu Yamauchi, Kimio Higashiyama

Synlett (10) 1431-1434 2011年査読有り
Dy(OTf)<inf>3</inf>/Pybox-catalyzed enantioselective Friedel-Crafts alkylation of indoles with α,β-unsaturated trifluoromethyl ketones

Shigeru Sasaki, Takayasu Yamauchi, Kimio Higashiyama

Tetrahedron Letters 51(17) 2326-2328 2010年4月査読有り
Regio- and stereoselective ring-opening reaction of chiral aziridines: A facile synthesis of chiral β-amino alcohols

Kimio Higashiyama, Masataka Matsumura, Hiroshi Kojima, Takayasu Yamauchi

Heterocycles 78(2) 471-485 2009年2月査読有り最終著者

もっとみる

MISC

パクリタキセルの創製と全合成

山内貴靖

星薬科大学紀要 (53) 109-116 2011年

書籍等出版物

スパイラル・ラーニング薬学有機化学下

山内貴靖 (担当:分担執筆)

京都廣川書店 2018年3月 (ISBN: 9784909197252)
スパイラル・ラーニング薬学有機化学上

山内貴靖 (担当:分担執筆)

京都廣川書店 2018年3月 (ISBN: 9784909197245)
薬学必須ラ・スパ

山内貴靖 (担当:分担執筆)

tecom 2017年6月 (ISBN: 9784863994058)

講演・口頭発表等

Developing new reactions toward green chemistry in pharmaceutical science

Takayasu Yamauchi

International Graduate Students Conference on Pharmaceutical Science 2018 2018年8月30日招待有り

担当経験のある科目(授業)

Works(作品等)

おとうと

2010年1月30日芸術活動

共同研究・競争的資金等の研究課題

学術貢献活動

新どうぶつ奇想天外

企画立案・運営等, 監修, 審査・評価, 学術調査立案・実施

2018年1月7日

山内貴靖

基本情報

研究キーワード

研究分野

論文

MISC

書籍等出版物

講演・口頭発表等

担当経験のある科目(授業)

Works(作品等)

共同研究・競争的資金等の研究課題

学術貢献活動

メニュー

共著者の一覧