FUKUI Kiyoshi


FUKUI Kiyoshi

J-GLOBAL         Last updated: Nov 1, 2019 at 16:25
 
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Name
FUKUI Kiyoshi
Affiliation
The University of Tokushima
Job title
Professor
Degree
Doctor of Medical Science (D.Med.Sc.)(Kyoto University)

Research Areas

 
 

Academic & Professional Experience

 
Apr 2019
 - 
Today
Vice President, Tokushima University
 
Apr 2019
 - 
Today
Director, International Center, Tokushima University
 
Apr 2019
 - 
Today
Visiting Professor, Institute for Enzyme Research, Tokushima University
 
Apr 2016
 - 
Mar 2019
Professor, Division of Enzyme Pathophysiology, Institute for Enzyme Research, Tokushima University
 
Apr 2012
 - 
Mar 2016
Director, Institute for Enzyme Research, Tokushima University
 
Apr 2007
 - 
Mar 2016
Professor, Division of Enzyme Pathophysiology, Institute for Enzyme Research, Tokushima University
 
Apr 1997
 - 
Mar 2007
Professor, Division of Gene Regulatorics, Institute for Enzyme Research, Tokushima University
 
1997
   
 
Professor, Institute for Enzyme Research,
 
1995
   
 
Professor, Institute for Enzyme Research,
 
1987
   
 
Chief Investigator,
 
1984
   
 
Investigator,
 
1979
   
 
Fellow in Medicine, Washington University School
 
 
   
 
The University of Tikushima
 
 
   
 
The University of Tokushima
 
 
   
 
National Cardiovascular Center Research Institute
 
 
   
 
National Cardiovascular Center Research Institute
 
 
   
 
of Medicine
 

Education

 
 
 - 
1984
Pathology, Graduate School, Division of Medicine, Kyoto University
 
 
 - 
1979
Professional Medical Course, Faculty of Medicine, Kyoto University
 

Committee Memberships

 
2000
   
 
The Vitamin Society of Japan  Councillor
 
1998
   
 
The Society of Cordiovasculor Endocrinology and Metabolism  Councillor
 
1995
   
 
The Japanese Biochemical Society  Councillor
 

Awards & Honors

 
Jun 2008
Award of the Vitamin Society of Japan
 
Oct 2004
Identification of a Novel, Embryonal Carcinoma Cell-associated Molecule, Nucling, That Is Up-regulated during Cardiac Muscle Differentiation, JB Award
Winner: Takashi Sakai, Li Liu, Yuji Shishido, Kiyoshi Fukui
 
1997
Kouraku-Prize
 
2004
The JB Prize
 

Published Papers

 
Soo Hyeon Kim, Yuji Shishido, Hirofumi Sogabe, Wanitcha Rachadech, Kazuko Yorita, Yusuke Kato, Kiyoshi Fukui
Journal of Biochemistry   166(2) 187-196   Aug 2019   [Refereed]
Yusuke Kato, Niyada Hin, Nobuo Maita, Ajit G. Thomas, Sumire Kurosawa, Camilo Rojas, Kazuko YORITA, Barbara S. Slusher, Kiyoshi Fukui, Takashi Tsukamoto
European Journal of Medicinal Chemistry   159 23-34   Nov 2018   [Refereed]
Yusuke Kato, Hiroshi Kihara, Kiyoshi Fukui, Masaki Kojima
Computational Biology and Chemistry   74 94-104   Jun 2018   [Refereed]
Akira Nishi, Shusuke Numata, Atsushi Tajima, Xiaolei Zhu, Koki Ito, Atsushi Saito, Yusuke Kato, Makoto Kinoshita, Shinji Shimodera, Shinji Ono, Shinichiro Ochi, Akira Imamura, Naohiro Kurotaki, Shu-Ichi Ueno, Nakao Iwata, Kiyoshi Fukui, Issei Imoto, Atsushi Kamiya, Tetsuro Ohmori
Scientific Reports   7(1) 2887-2887   Jun 2017   [Refereed]
Here we report de novo non-synonymous single-nucleotide variants (SNVs) by conducting whole exome sequencing of 18 trios consisting of Japanese patients with sporadic schizophrenia and their parents. Among nine SNVs, we explored the functional imp...
Taiki Kohiki, Yusuke Kato, Yusuke Nishikawa, Kazuko YORITA, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Akira Shigenaga, Kiyoshi Fukui, Akira Otaka
Organic & Biomolecular Chemistry   15(25) 5289-5297   May 2017   [Refereed]
Do Youn Jun, Hyejin Kim, Won Young Jang, Ji Young Lee, Kiyoshi Fukui, Young Ho Kim
PLoS ONE   12(5) e0176544   May 2017   [Refereed]
Human lysosomal-associated protein multispanning membrane 5 (LAPTM5) was identified by an ordered differential display-polymerase chain reaction (ODD-PCR) as an up-regulated cDNA fragment during 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced d...
Yusuke Kato, Kiyoshi Fukui
The Journal of Biochemistry   Vol.161(No.2) 223-230   Feb 2017   [Refereed]
Shohei Toguchi, Tomoyasu Hirose, Kazuko YORITA, Kiyoshi Fukui, Barry K Sharpless, Satoshi Omura, Toshiaki Sunazuka
Chemical & Pharmaceutical Bulletin   64(7) 695-703   Jul 2016   [Refereed]
In situ click chemistry is a target-guided synthesis approach for discovering novel lead compounds by assembling organic azides and alkynes into triazoles inside the affinity site of target biogenic molecules such as proteins. We report in situ cl...
Yusuke Kato, Kiyoshi Fukui, Kazuo Suzuki
Protein and Peptide Letters   23(4) 372-378   Apr 2016   [Refereed]
Avian influenza H5N1 has shown high mortality rate in human. Non-structural protein 1 (NS1) is a virulence factor of H5N1. Mutation at the 42nd residue within the RNA-binding domain (RBD) of NS1 dramatically changes the degree of pathogenicity of ...
トリインフルエンザH5N1を高病原性化するNon-structural protein 1における変異のタンパク質分子機構
Yusuke Kato, Kiyoshi Fukui, Kazuo Suzuki
バイオイメージング   25(1) 30-31   2016   [Refereed]
Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
Journal of Pharmaceutical and Biomedical Analysis   116 94-100   Dec 2015   [Refereed]
d-Amino acid oxidase (DAO) is a flavoenzyme that metabolizes d-amino acids and is expected to be a promising therapeutic target of schizophrenia and glioblastoma. The study of DNA-binding proteins has yielded much information in the regulation of ...
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
The Journal of Biological Chemistry   290(40) 24626-24635   Oct 2015   [Refereed]
Postpartum mammary gland involution is the physiological process by which the lactating gland returns to its pre-pregnant state. In rodent models, the microenvironment of mammary gland involution is sufficient to induce enhanced tumor cell growth,...
Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The Journal of Biochemistry   157(5) 377-387   May 2015   [Refereed]
D-amino acid oxidase (DAO) is a flavoenzyme that metabolizes d-amino acids. Until now, the DAO expression mechanism is still unclear. Our assessment of human DAO (hDAO) promoter activity using luciferase reporter system indicated the proximal upst...
Kiyoshi Fukui
ビタミン   88(10) 524-529   Oct 2014   [Refereed]
Miho Shishikura, Hitomi Hakariya, Sumiko Iwasa, Takashi Yoshio, Hideaki Ichiba, Kazuko YORITA, Kiyoshi Fukui, Takeshi Fukushima
Bioscience Trends   8(3) 149-154   Jun 2014   [Refereed]
It is of importance to determine whether antipsychotic drugs currently prescribed for schizophrenia exert D-amino acid oxidase (DAO)-inhibitory effects. We first investigated whether human (h)DAO can metabolize D-kynurenine (D-KYN) to produce the ...
Kiyoshi Fukui, Yuji Shishido, Kazuko YORITA, Takashi Sakai
BIO INDUSTRY   31(3) 11-16   Mar 2014   [Refereed][Invited]
Sayuri Ishiwata, Asami Umino, Masakazu Umino, Kazuko YORITA, Kiyoshi Fukui, Toru Nishikawa
The International Journal of Neuropsychopharmacology   16(6) 1395-1406   Jul 2013   [Refereed]
In mammalian brains, d-serine has been shown to be required for the regulation of glutamate neurotransmission as an endogenous co-agonist for the N-methyl-d-aspartate type glutamate receptor that is essential for the expression of higher-order bra...
Norihiro Shibuya, Shin Koike, Makiko Tanaka, Mari Ishigami-Yuasa, Yuka Kimura, Yuki Ogasawara, Kiyoshi Fukui, Noriyuki Nagahara, Hideo Kimura
Nature Communications   4 e1366   Jan 2013   [Refereed]
In eukaryotes, hydrogen sulphide acts as a signalling molecule and cytoprotectant. Hydrogen sulphide is known to be produced from L-cysteine by cystathionine -synthase, cystathionine -lyase and 3-mercaptopyruvate sulfurtransferase coupled with cys...
Sun Mi Kim, Takashi Sakai, Huy Van Dang, Nam Hoang Tran, Koji Ono, Kazunori Ishimura, Kiyoshi Fukui
The Journal of Biochemistry   153(1) 93-101   Jan 2013   [Refereed]
Nucling is a proapoptotic protein that regulates the apoptosome and nuclear factor-kappa B (NF-B) signalling pathways. Strong stimuli, such as Gram-negative bacterial lipopolysaccharide (LPS), induce the simultaneous secretion of cytokines followi...
Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Seongpil Chung, Diem Hong Tran, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui
Journal of Bioenergetics and Biomembranes   44(5) 513-523   Oct 2012   [Refereed]
Angiogenesis is critical for cancer growth and metastasis. Steps of angiogenesis are energy consuming, while vascular endothelial cells are highly glycolytic. Glioblastoma multiforme (GBM) is a highly vascular tumor and this enhances its aggressiv...
Koji Ono, Yuji Shishido, Hwan Ki Park, Rabab Mohamed Abou EL-Magd, Seongpil Chung, Kazuko YORITA, Nobuya Sano, Arima Kunimasa, Takashi Sakai, Kazunori Ishimura, Kiyoshi Fukui
ビタミン   86(7) 395-397   Jul 2012   [Refereed]
Kaori Kiso, Satoko Ueno, Mana Fukuda, Ikuyo Ichi, Keiko Kobayashi, Takashi Sakai, Kiyoshi Fukui, Shousuke Kojo
Biological & Pharmaceutical Bulletin   35(6) 980-983   Jun 2012   [Refereed]
Carbon tetrachloride (CCl(4))-induced acute hepatitis is assumed to involve two phases. The initial phase, initiated within 2 h after CCl(4) administration, involves the generation of reactive oxygen species. The second phase is assumed to start a...
Salah Mohamed El-Sayed, Rabab Mohamed Abou EL-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui
Journal of Bioenergetics and Biomembranes   44(1) 61-79   Feb 2012   [Refereed]
Oxidative stress-energy depletion therapy using oxidative stress induced by D-amino acid oxidase (DAO) and energy depletion induced by 3-bromopyruvate (3BP) was reported recently (El Sayed et al., Cancer Gene Ther., 19, 1-18, 2012). Even in the pr...
Kiyoshi Fukui
ビタミン   86(2) 63-73   Feb 2012   [Refereed]
D-Amino acid oxidase (DAO) has been proposed to be involved in the decreased glutamatergic neurotransmission in schizophrenia and the modulation of its activity is expected to be therapeutic. Here we show the inhibitory effect of antipsychotic dru...
Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui
Cancer Gene Therapy   19(1) 1-18   Jan 2012   [Refereed]
Glioma tumors are refractory to conventional treatment. Glioblastoma multiforme is the most aggressive type of primary brain tumors in humans. In this study, we introduce oxidative stress-energy depletion (OSED) therapy as a new suggested treatmen...
Seongpil Chung, Sogabe Kimiko, Hwan Ki Park, Ying Song, Koji Ono, Rabab Mohamed Abou El-Magd, Yuji Shishido, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The Journal of Biochemistry   148(6) 743-753   Dec 2010   [Refereed]
D-amino acid oxidase (DAO) is a flavoenzyme that exists in the kidney, liver and brain of mammals. This enzyme catalyzes the oxidation of D-amino acids to the corresponding -keto acid, hydrogen peroxide and ammonia. Recently D-serine, one of the s...
Rabab Mohamed Abou El-Magd, Chizuru Sasaki, Tomoya Kawazoe, Salah M. El-Sayed, Kazuko YORITA, Yuji Shishido, Takashi Sakai, Yoshitoshi Nakamura, Kiyoshi Fukui
Biochemical Engineering Journal   52(2-3) 236-247   Nov 2010   [Refereed]
Nam Hoang Tran, Takashi Sakai, Sun Mi Kim, Kiyoshi Fukui
The Journal of Biochemistry   148(5) 573-580   Nov 2010   [Refereed]
Nucling is identified as a novel regulator of apoptosis. In this study, we investigated the nuclear factor-B (NF-B)-dependent mechanism of Nucling expression, as well as the degradation pathways mediated by proteasome system and caspase activation...
Rabab Mohamed Abou El-Magd, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Seongpil Chung, Motoshige Miyano, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
Journal of Psychopharmacology   24(7) 1055-1067   Jul 2010   [Refereed]
D-Amino acid oxidase (DAO) has been established to be involved in the oxidation of D-serine, an allosteric activator of the N-methyl-D-aspartate-type glutamate receptor in the brain, and to be associated with the onset of schizophrenia. The effect...
Takashi Sakai, Li Liu, Xichuan Teng, Naozumi Ishimaru, Rika Mukai-Sakai, Nam Hoang Tran, Sun Mi Kim, Nobuya Sano, Yoshio Hayashi, Ryuji Kaji, Kiyoshi Fukui
International Journal of Cancer   126(5) 1079-1094   Mar 2010   [Refereed]
Nucling is a stress-inducible protein associated with apoptosomes. The cytochrome c-triggered formation of apoptosomes represents a key-initiating event in apoptosis. We have recently reported that Nucling regulates the apoptotic pathway by contro...
Koji Ono, Yuji Shishido, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Seongpil Chung, Rabab M. Abou El-Magd, Kazuko YORITA, Mai Okano, Takeshi Watanabe, Nobuya Sano, Yoshimi Bando, Kunimasa Arima, Takashi Sakai, Kiyoshi Fukui
Journal of Neural Transmission   116(10) 1335-1347   Sep 2009   [Refereed]
D-Amino acid oxidase (DAO) is a peroxisomal flavoenzyme that catalyzes oxidative deamination of a wide range of D-amino acids. Among the possible substrates of DAO in vivo, D-serine is proposed to be a neuromodulator of the N-methyl-D-aspartate (N...
Li Liu, Takashi Sakai, Nam Hoang Tran, Rika Mukai-Sakai, Ryuji Kaji, Kiyoshi Fukui
The FEBS Journal   276(5) 1459-1470   Mar 2009   [Refereed]
Nucling is an Apaf1-binding proapoptotic protein involved in apoptosome-mediated apoptosis. Luciferase assays have revealed that the activation of nuclear factor-kappaB induced by tumor necrosis factor-alpha, interleukin-1beta and lipopolysacchari...
Kiyoshi Fukui
Seikagaku   80(4) 344-351   Apr 2008   [Refereed]
Sanae Iwana, Tomoya Kawazoe, Hwan Ki Park, Koichiro Tsuchiya, Koji Ono, Kazuko YORITA, Takashi Sakai, Takenori Kusumi, Kiyoshi Fukui
Journal of Enzyme Inhibition and Medicinal Chemistry   23(6) 901-911   Dec 2008   [Refereed]
Jun DY, Park HS, Lee JY, Baek JY, Park HK, Fukui K, Kim YH
GENE   414(1-2) 106-114   May 2008   [Refereed]
Tomoya Kawazoe, Hwan Ki Park, Sanae Iwana, Hideaki Tsuge, Kiyoshi Fukui
Chemical Record   7(5) 305-315   Oct 2007   [Refereed]
Tomoya Kawazoe, Hideaki Tsuge, Mirella S. Pilone, Kiyoshi Fukui
Biochemical and Biophysical Research Communications   355(2) 385-391   Apr 2007   [Refereed]
Jie Shu Li, Yasufumi Umena, Kazuko YORITA, Takeshi Matsuoka, Akiko Kita, Kiyoshi Fukui, Yukio Morimoto
Biochemical and Biophysical Research Communications   358(4) 1002-1007   Jul 2007   [Refereed]
Takashi Sakai, Kiyoshi Fukui
Seikagaku   78(9) 867-871   Sep 2006   [Refereed]
Tomoya Kawazoe, Hideaki Tsuge, Mirella S. Pilone, Kiyoshi Fukui
Protein Science   15(12) 2708-2717   Dec 2006   [Refereed]
Hwan Ki Park, Yuji Shishido, Sayaka Ichise-Shishido, Tomoya Kawazoe, Koji Ono, Sanae Iwana, Yumiko Tomita, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
Journal of Biochemistry   139(2) 295-304   Feb 2006   [Refereed]
Xichuan Teng, Takashi Sakai, Li Liu, Rika Sakai, Ryuji Kaji, Kiyoshi Fukui
Journal of Neurochemistry   97(4) 1126-1135   May 2006   [Refereed]
Yasufumi Umena, Kazuko YORITA, Takeshi Matsuoka, Akiko Kita, Kiyoshi Fukui, Yukio Morimoto
Biochemical and Biophysical Research Communications   350(2) 249-256   Nov 2006   [Refereed]
Gianluca Molla, Silvia Sacchi, Mariagrazia Bernasconi, Mirella S. Pilone, Kiyoshi Fukui, Loredano Pollegioni
FEBS Letters   580(9) 2358-2364   Apr 2006   [Refereed]
Functional Roles and Pathophysiology of Brain D-Amino Acid Oxidase
Kiyoshi Fukui, Hwan Ki Park, Tomoya Kawazoe, Koji Ono, Sanae Iwana, Yumiko Tomita, Kazuko YORITA, Takashi Sakai, Young Ho Kim
Flavins and Flavoproteins 2005   853-860   Dec 2005   [Refereed]
D-Amino acid oxidase (D-amino acid: O2 oxidoreductase, DAO; EC 1.4.3.3) is a flavoenzyme with noncovalently bound FAD as its prosthetic group, that catalyzes the oxidative deamination of wide range of D-amino acids to the corresponding imino acids...
Molecular Basis of Schizophrenia: Characterization of Human D-Amino Acid Oxidase
Gianluca Molla, Mirella S. Pilone, Silvia Sacchi, Mariagrazia Bernasconi, Kiyoshi Fukui, Loredano Pollegioni
Flavins and Flavoproteins 2005   861-866   Dec 2005   [Refereed]
Purification and Crystal Structure of Human D-Amino Acid Oxidase
Tomoya Kawazoe, Sanae Iwana, Koji Ono, Hwan Ki Park, Kazuko YORITA, Yumiko Tomita, Hideaki Tsuge, Kiyoshi Fukui
Flavins and Flavoproteins 2005   33-36   Dec 2005   [Refereed]
H265Q L-Lactate Oxidase from Aerococcus viridans
Kazuko YORITA, Takeshi Matsukoa, David P. Ballou, Kiyoshi Fukui
Flavins and Flavoproteins 2005   37-41   Dec 2005   [Refereed]
Crystal Structures of Wild-type and R181M L-Lactate Oxidase from Aerococcus viridans
Kazuko YORITA, Yasufumi Umena, Takeshi Matsuoka, David P. Ballou, Makoto Abe, Akiko Kita, Tomitake Tsukihara, Yukio Morimoto, Kiyoshi Fukui
Flavins and Flavoproteins 2005   43-48   Dec 2005   [Refereed]
Astroglial D-amino acid oxidase is the key enzyme to metabolize extracellular D-serine, a neuromodulator of N-methyl-D-aspartate receptor
Kiyoshi Fukui, Hwan Ki Park, Tomoya Kawazoe, Koji Ono, Sanae Iwana, Kazuko YORITA, Takashi Sakai
Amino Acids   29(1) 61-62   Jul 2005   [Refereed]
Yasufumi Umena, Kazuko YORITA, Takeshi Matsuoka, Makoto Abe, Akiko Kita, Kiyoshi Fukui, Tomitake Tsukihara, Yukio Morimoto
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications   61(4) 439-441   Apr 2005   [Refereed]
L-Lactate oxidase (LOX) from Aerococcus viridans is a member of the alpha-hydroxyacid oxidase flavoenzyme family. An X-ray crystallographic study of a LOX mutant in which Arg181 is replaced by Met was initiated in order to understand the functions...
Tomoya Kawazoe, Koji Ono, Ki Hwan Park, Kazuko YORITA, Yumiko Tomita, Kiyoshi Fukui
化学と生物   42(7) 426-428   Jul 2004   [Refereed]
Sakai T, Liu L, Teng X, Mukai-Sakai R, Shimada H, Kaji R, Mitani T, Matsumoto M, Toida K, Ishimura K, Shishido Y, Mak TW, Fukui K
Journal of Biological Chemistry   279(39) 41131-41140   2004   [Refereed]
Liu L, Sakai T, Sano N, Fukui K
Biochemical Journal   380(1) 31-41   2004   [Refereed]
Sakai T, Liu L, Shishido Y, Fukui K
Journal of Biochemistry   133(4) 429-436   2003   [Refereed]
Astroglial expression of D-amino acid oxidase gene
Atsuhiko Suzue, Shinji Nagahiro, Yoshiteru Urai, Osamu Jinnouchi, Tokujiro Kanamori, Kyung Tak Kwak, Hwan Ki Park, Tomoya Kawazoe, Sayaka Ichise, Yuji Shishido, Yumiko Tomita, Takashi Sakai, Kiyoshi Fukui
Flavins and Flavoproteins 2002   853-856   Dec 2002   [Refereed]
Urai Y, Jinnouchi O, Kwak KT, Suzue A, Nagahiro S, Fukui K
Neuroscience Letters   324(2) 101-104   2002   [Refereed]
Ming Li, Azusa Marubayashi, Yutaka Nakaya, Kiyoshi Fukui, Seiji Arase
The Journal of Investigative Dermatology   117(6) 1594-1600   Dec 2001   [Refereed]
The mechanism by which minoxidil, an adenosine-triphosphate-sensitive potassium channel opener, induces hypertrichosis remains to be elucidated. Minoxidil has been reported to stimulate the production of vascular endothelial growth factor, a possi...
Yoshihisa Shimizu, Tomohiro Akashi, Asuko Okuda, Akihiko Kikuchi, Kiyoshi Fukui
Gene   246(1-2) 395-404   Apr 2000   [Refereed]
Nap1p is identified in mammalian cell extract by its intrinsic activity to facilitate nucleosome assembly in vitro in the physiological ionic condition. The homologous proteins are present in most eukaryotes, and their functional analyses in vitro...
Chie Yuasa, Osamu Miyoshi, Kiyoshi Fukui, Toshinori Oka
Journal of Nutritional Science and Vitaminology   Vol.46(No.6) 297-301   Jan 2000   [Refereed]
The pathogenesis of alcoholic pancreatitis is unknown, and even though hyperlipemia has been hypothesized to be a risk factor for alcoholic pancreatitis, no studies directly investigating whether there is a relationship between the two have ever b...
Raibekas AA, Fukui K, Massey V
Proceedings of the National Academy of Sciences of the United States of America   97(7) 3089-3093   2000   [Refereed]
Gene Expression of D-Amino Acid Oxidase in Nervous System
Tokujiro Kanamori, Mariko Obayashi, Osamu Jinnouchi, Kazuya Kanda, Yoshiteru Uari, Yuji Shishido, Atsuhiko Suzue, Takashi Sakai, Kiyoshi Fukui
Flavins and Flavoproteins 1999   887-890   Dec 1999   [Refereed]
Chie Yuasa, Kenji Irimura, Minoru Oda, Kiyoshi Fukui, Toshinori Oka
The Journal of Pharmacy and Pharmacology   51(7) 867-871   Jul 1999   [Refereed]
Osamu Jinnouchi, Yasuo Koike, Kiyoshi Fukui
Practica Oto-Rhino-Laryngologica suppl.   101 1-6   Jan 1999   [Refereed]
Osamu Jinnouchi, Yasuo Koike, Kiyoshi Fukui
Audiology Japan   41 359-360   Sep 1998   [Refereed]
Molecular biological study on the function and signal transduction of novel vasoactive mediator
Kiyoshi Fukui, Yumiko Tomita, Takashi Sakai, Yoshihisa Shimizu, Kazuya Kanda
Research Report of Takeda Medical Research Foundation   25 61-65   Jan 1998
Masatsugu Nakai, Jun Ogata, Kiyoshi Fukui, Y Nakai, Michiyuki Maeda
Neuroscience   79(2) 571-579   May 1997   [Refereed]
Ryuichi Konno, Masato Sasaki, Setsuko Asakura, Kiyoshi Fukui, Jumpei Enami, Akira Niwa
Biochimica et Biophysica Acta (BBA) - General Subjects   1335(1-2) 173-181   Apr 1997   [Refereed]
Since there are conflict reports on the presence of D-amino-acid oxidase in the mouse liver, this problem was examined. D-Amino-acid oxidase activity was not detected in the homogenates of the mouse liver, lung, or heart, whereas it was detected i...
Is There D-Amino acid oxidase in the Mouse Liver?
Ryuichi Konno, Akira Niwa, Masato Sasaki, Jumpei Enami, Setsuko Asakura, Kiyoshi Fukui
Flavins and Flavoproteins 1996   203-206   Jan 1997   [Refereed]
Tissue Specific Expression of the D-Amino Acid Oxidase Gene
Kiyoshi Fukui, Tokujiro Kanamori, Osamu Jinnouchi, Oded Ben-Yoseph
Flavins and Flavoproteins 1996   199-202   Jan 1997   [Refereed]
中井 正継, 緒方 絢, 玉城 欣也, 山本 仁, Kiyoshi Fukui, 松井 征男, 前田 正信
Advances in Neurological Sciences   40(4) 527-539   Aug 1996   [Refereed]
Uptake of radioactive octanoate in astrocytoma cells: Basic Studies for application of [11C] octanoate as a PET tracer
Shunji Yamazaki, Kiyoshi Fukui, Hidefumi Kawashima, Yuji Kuge, Yoshihiro Miyake, Kenji Kangawa
Annals of Nuclear Medicine   10(4) 395-399   Jan 1996   [Refereed]
Localization of the candidate gene D-Amino Acid Oxidase outside the refined 1-cM region of Spinocerebellar Ataxia 2 (SCA2)
Suzana Gispert, Astrid Lunkes, Nieves Santos, Guillermo Orozco, Duc Ha-Hao, Tim Ratzlaff, Jorge Aguiar, Isis Torrens, Luis Heredero, Alexis Brice, Geraldine Cancel, Giovanni Stevanin, Jean-Claude Vernant, Alexandra Durr, Agnes Lepage-Lezin, Samir Belal, Mongi Ben-Hamida, Stephan Pulst, Guy Rouleau, Jean Weissenbach, Denis LePaslier, Raju Kucherlapati, Kate Montgomery, Kiyoshi Fukui, Georg Auburger
American Journal of Human Genetics   57(4) 972-975   Oct 1995   [Refereed]
大脳皮質循環を拡張性に調節する中枢神経領域
中井 正継, 緒方 絢, 玉城 欣也, 山本 仁, Kiyoshi Fukui, 松井 征男, 前田 正信
Recent Advances in Cardiovascular Disease   16 95-113   Aug 1995   [Refereed]
Studies on the Kinetic Mechanism of Pig Kidney D-Amino Acid Oxidase by Site-directed Mutagenesis of Tyrosine 224 and Tyrosine 228
Loredano Pollegioni, Kiyoshi Fukui, Vincent Massey
The Journal of Biological Chemistry   269(50) 31666-31673   Dec 1994   [Refereed]
組織レニン・アンジオテンシン系と高血圧遺伝子研究
Kiyoshi Fukui
Recent Advances in Cardiovascular Disease   15 83-91   Jun 1994   [Refereed]
Structure of Human D-Amino Acid Oxidase Gene
Kiyoshi Fukui
Flavins and Flavoproteins 1993   159-162   Jan 1994   [Refereed]
Structure and Function of Renin-Binding Protein
Saori Takahashi, Hiroyasu Inoue, Kiyoshi Fukui, Yoshihiro Miyake
Kidney International   46 1525-1527   Dec 1994   [Refereed]
Molecular Cloning and Chromosomal Localization of a Human Gene Encoding D-Amino Acid Oxidase
Kiyoshi Fukui, Yoshihiro Miyake
Journal of Biological Chemistry   267 18631-18638   Sep 1992   [Refereed]
Genetic and Molecular Properties of Human and Rat Renin-Binding Proteins with Reference to the Function of the Leucine Zipper Motif
Hiroyasu Inoue, Saori Takahashi, Kiyoshi Fukui, Yoshihiro Miyake
The Journal of Biochemistry   110(4) 493-500   Oct 1991   [Refereed]
Leucine Zipper Motif in Porcine Renin-binding Protein (RnBP) and Its Relationship to the Formation of an RnBP-Renin Heterodimer and an RnBP Homodimer
Hiroyasu Inoue, Saori Takahashi, Kiyoshi Fukui, Yoshihiro Miyake
Journal of Biological Chemistry   266(18) 11896-11900   Jun 1991   [Refereed]
Studies on Phe-228 and Leu-307 Recombinant Mutants of Porcine Kidney D-Amino Acid Oxidases
Motoshige Miyano, Kiyoshi Fukui, Fusao Watanabe, Saori Takahashi, Masazumi Tada, Masaru Kanashiro, Yoshihiro Miyake
Journal of Biochemistry   109(1) 171-177   Jan 1991   [Refereed]
Expression of Mouse Kidney D-Amino Acid Oxidase in Escherichia Coli
Masazumi Tada, Kiyoshi Fukui, Motoshige Miyano, Yoshihiro Miyake
Flavins and Flavoproteins 1990   147-150   Jan 1991   [Refereed]
Purification of Recombinant Mutant Porcine D-Amino Acid Oxidases
Motoshige Miyano, Kiyoshi Fukui, Fusao Watanabe, Masazumi Tada, Saori Takahashi, Yoshihiro Miyake
Flavins and Flavoproteins 1990   151-154   Jan 1991   [Refereed]
Molecular Biological Studies on Structure-Function Relationship of D-Amino Acid Oxidase
Yoshihiro Miyake, Kiyoshi Fukui, Kyoko Momoi, Fusao Watanabe, Masazumi Tada, Motoshige Miyano, Saori Takahashi
Flavins and Flavoproteins 1990   135-142   Jan 1991   [Refereed]
Genomic Organization and Expression of D-Amino Acid Oxidase Gene
Kiyoshi Fukui, Kyoko Momoi, Fusao Watanabe, Masazumi Tada, Motoshige Miyano, Yoshihiro Miyake
Flavins and Flavoproteins 1990   143-146   Jan 1991   [Refereed]
Kiyoshi Fukui, Yoshihiro Miyake
ビタミン   Vol.64(No.9) 546-548   Sep 1990   [Refereed]
Gene Expression of D-Amino Acid Oxidase in Rabbit Kidney
Kyoko Momoi, Kiyoshi Fukui, Masazumi Tada, Yoshihiro Miyake
Journal of Biochemistry   108(3) 406-413   Sep 1990   [Refereed]
Masazumi Tada, Kiyoshi Fukui, Kyoko Momoi, Yoshihiro Miyake
Gene   90(2) 293-297   Jun 1990   [Refereed]
Molecular Cloning and Sequence Analysis of a cDNA Encoding a Porcine Kidney Renin-binding Protein
Hiroyasu Inoue, Kiyoshi Fukui, Saori Takahashi, Yoshihiro Miyake
Journal of Biological Chemistry   265(12) 6556-6561   Apr 1990   [Refereed]
Fusao Watanabe, Kiyoshi Fukui, Kyoko Momoi, Yoshihiro Miyake
Biochemical and Biophysical Research Communications   165(3) 1422-1427   Dec 1989   [Refereed]
Kiyoshi Fukui, Hiroyasu Inoue, Saori Takahashi, Yoshihiro Miyake
Biochemical and Biophysical Research Communications   164(1) 265-270   Oct 1989   [Refereed]
Site-specific Mutagenesis of Lysine-204, Tyrosine-224, Tyrosine-228, and Histidine-307 of Porcine Kidney D-Amino Acid Oxidase and the Implications as to Its Catalytic Function
Fusao Watanabe, Kiyoshi Fukui, Kyoko Momoi, Yoshihiro Miyake
Journal of Biochemistry   105(6) 1024-1029   Jun 1989   [Refereed]
Identification and Structure of the Rat True Tissue Kallikrein Gene Expressed in the Kidney.
Hiroyasu Inoue, Kiyoshi Fukui, Yoshihiro Miyake
Journal of Biochemistry   105(5) 834-840   May 1989   [Refereed]
Fusao Watanabe, Kiyoshi Fukui, Kyoko Momoi, Yoshihiro Miyake
FEBS Letters   238(2) 269-272   Oct 1988   [Refereed]
Kyoko Momoi, Kiyoshi Fukui, Fusao Watanabe, Yoshihiro Miyake
FEBS Letters   238(1) 180-184   Sep 1988   [Refereed]
Kiyoshi Fukui, Kyoko Momoi, Fusao Watanabe, Yoshihiro Miyake
Biochemistry   27(18) 6693-6697   Sep 1988   [Refereed]
Biological and Medical Aspects of D-Amino Acid Oxidase
Yoshihiro Miyake, Kiyoshi Fukui, Kyoko Momoi, Fusao Watanabe, Toshihiro Shibata
Flavins and Flavoproteins 1987   501-508   Jan 1988   [Refereed]
Molecular and Cellular Biology of D-Amino Acid Oxidase
Kiyoshi Fukui, Fusao Watanabe, Toshihiro Shibata, Kyoko Momoi, Yoshihiro Miyake
Flavins and Flavoproteins 1987   509-512   Jan 1988   [Refereed]
Secreted Proteins of Human Monocytes
James R. Panuska, Kiyoshi Fukui, Charles W. Parker
The Biochemical Journal   249(2) 501-511   Jan 1988   [Refereed]

Misc

 
生体不斉アミノ酸分子の存在とその代謝酵素の病態生理学的意義
Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
日本応用酵素協会誌   41 21-31   Feb 2007   [Invited]
D-アミノ酸代謝システムによる脳機能制御の医化学
Sanae Iwana, Kiyoshi Fukui
Farumashia   41(9) 857-861   Sep 2005   [Invited]
Regulation of Mammalian Brain Function by D-amino Acid Biosystem---Roles of Endogenous D-serine and D-amino Acid Oxidase
Kawazoe T, Ono K, Park HK, Yorita K, Tomita Y, Fukui K
Chemistry & Biology   42(7) 426-428   2004

Books etc

 
D-Amino Acids --Physiology, Metabolism, and Application --
Yusuke Kato, Diem Hong Tran, Huong Thi Thanh Trinh, Kiyoshi Fukui (Part:Contributor, Chapter 19: D-Amino Acid Oxidase and D-Aspartate Oxidase)
Springer   Sep 2016   ISBN:978-4431560753
ビタミン総合事典
Kiyoshi Fukui (Part:Contributor)
朝倉書店   Nov 2010   ISBN:4-254-10228-3
タンパク質・アミノ酸の新栄養学
Kiyoshi Fukui (Part:Contributor, 第Ⅰ編タンパク質・アミノ酸の化学と代謝 第6章アミノ酸代謝)
株式会社 講談社サイエンティフィク   Mar 2007   ISBN:4-061-53686-9
D-Amino Acids: A New Frontier in Amino Acid and Protein Research - Practical Methods and Protocols
Hwan Ki Park, Yoshiteru Urai, Osamu Jinnouchi, Atsuhiko Suzue, Tokujiro Kanamori, Kyung Tak Kwak, Oded-Ben Yoseph, Shinji Nagahiro, Kiyoshi Fukui (Part:Contributor, 6-12 Astroglial expression of D-amino acid oxidase; regional and cell-type specific expression)
Nova Science Publishers   Jan 2007   ISBN:978-1600210754
廣川タンパク質化学4 酵素 4.1 オキシドレダクターゼ
Yoshihiro Miyake, Kiyoshi Fukui (Part:Contributor, 第15章 D-アミノ酸オキシダーゼ)
株式会社 廣川書店   Feb 2000   ISBN:4-567-16040-1
シリーズ分子生物学4 医学分子生物学
Kiyoshi Fukui (Part:Contributor, 第2章病気の分子生物学 第2節循環器系)
朝倉書店   Nov 1997   ISBN:4-254-17574-4
最新内科学大系6 肥満症,臨床栄養
Yoshihiro Miyake, Kiyoshi Fukui (Part:Contributor, XIII-ビタミン・カルシウムとその異常 c.ビタミンC)
Nakayama-Shoten Co., Ltd.   Nov 1995   ISBN:4-521-40641-6
Experimental Manual for Immunology 1
Kiyoshi Fukui (Part:Contributor, Southern Blotting)
Nankodo   Mar 1995   ISBN:4-524-20603-5

Conference Activities & Talks

 
生体内各組織におけるD-アミノ酸酸化酵素活性の検出とその生理的意義の考察
SooHyeon Kim, Yuji Shishido, Hirofumi Sogabe, Wanitcha Rachadech, Yusuke Kato, Kiyoshi Fukui
第454回研究協議会   20 Oct 2018   ビタミンB研究委員会
Combined approach of computation and enzymology to investigate novel D-amino acid oxidase inhibitors
Yusuke Kato, Nobuo Maita, Taiki Kohiki, Sumire Kurosawa, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Kazuko YORITA, Akira Shigenaga, Akira Otaka, Kiyoshi Fukui
The 13th International Symposium of the Institute Network for Biomedical Sciences joint with the 3rd Symposium of the Inter-University Research Network for Trans-Omics Medicine and the 28th Hot Spring Harbor Symposium   18 Oct 2018   Institute Network for Biomedical Science
アストログリアにおける自然免疫系によるD-アミノ酸酸化酵素遺伝子の発現調節
Yuji Shishido, Hirofumi Sogabe, SooHyeon Kim, Rachadech Wanitcha, Yusuke Kato, Kiyoshi Fukui
The 91st Annual Meeting of the Japanese Biochemical Society   26 Sep 2018   The Japanese Biochemical Society
Distribution of D-amino acid oxidase activity in mouse brain regions and peripheral tissues examined by enzyme-coupled colorimetric assay
SooHyeon Kim, Yuji Shishido, Hirofumi Sogabe, Rachadech Wanitcha, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
The 91st Annual Meeting of the Japanese Biochemical Society   26 Sep 2018   The Japanese Biochemical Society
新規NF-κB制御分子ヌクリングはインスリンの発現制御に関与している
Bunrin Rin, Hirofumi Sogabe, Yuji Shishido, Kiyoshi Fukui, Kiyoshi Fukui, Takashi Sakai
The 91st Annual Meeting of the Japanese Biochemical Society   26 Sep 2018   The Japanese Biochemical Society
自然免疫とヒト D-アミノ酸酸化酵素遺伝子の発現調節機構
Yuji Shishido, Hirofumi Sogabe, Hyeon Soo Kim, Rachadech Wanitcha, Yusuke Kato, Kiyoshi Fukui
第14回 D-アミノ酸研究会学術講演会   6 Sep 2018   D-アミノ酸学会
統合失調症におけるde novo変異(突然変異)研究
西 晃, Shusuke Numata, Atsushi Tajima, Xiaolei Zhu, 伊藤 候輝, 斎藤 淳, Yusuke Kato, Makoto Kinoshita, 下寺 信次, 小野 慎治, 越智 紳一郎, 今村 明, 黒滝 直弘, Shu-ichi Ueno, 岩田 仲生, Kiyoshi Fukui, Issei Imoto, 神谷 篤, Tetsuro Ohmori
第13回日本統合失調症学会   23 Mar 2018   
生理活性物質硫化水素とポリサルファイドの産生機構
渋谷 典広, 小池 伸, 宮本 亮, 湯浅 磨里, 田中 真紀子, 木村 由佳, 高野 陽子, 花岡 健二郎, 永原 則之, Kiyoshi Fukui, 浦野 泰照, 小笠原 祐樹, 木村 英雄
2017年度生命科学系学会合同年次大会   8 Dec 2017   The Japanese Biochemical Society
ミクログリアにおけるD-アミノ酸酸化酵素遺伝子の発現調節機構の解明
Yuji Shishido, Hirofumi Sogabe, SooHyeon Kim, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
2017年度生命科学系学会合同年次大会   8 Dec 2017   The Japanese Biochemical Society
哺乳動物細胞におけるD-アミノ酸酸化酵素タンパク質の代謝経路の解析
Hirofumi Sogabe, Yuji Shishido, SooHyeon Kim, Wanitcha Rachadech, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
2017年度生命科学系学会合同年次大会   8 Dec 2017   The Japanese Biochemical Society
DAO分子表面に結合する阻害分子の計算科学的解析
Yusuke Kato, Taiki Kohiki, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Akira Shigenaga, Akira Otaka, Kiyoshi Fukui
2017年度生命科学系学会合同年次大会   7 Dec 2017   The Japanese Biochemical Society
B型インフルエンザ ノイラミニダーゼの薬物耐性機構の解析に向けて
Yusuke Kato, 伊藤 吹夕, 髙橋 和浩, 菅又 龍一, 鈴木 章一, 山本 友子, 河内 正治, Kiyoshi Fukui, 三牧 正和, Kazuo Suzuki
第23回MPO研究会   2 Dec 2017   
Studies on binding molecules to D-amino acid oxidase using computational approaches
Yusuke Kato, Taiki Kohiki, Yusuke Nishikawa, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Yuji Shishido, Akira Shigenaga, Akira Otaka, Kiyoshi Fukui
The 12th International Symposium of the Institute Network, Tokyo   28 Nov 2017   
脳内D-アミノ酸代謝システムをターゲットとした疾患酵素学研究 [Invited]
Kiyoshi Fukui
第28回 フォーラム・イン・ドージン「D-アミノ酸生物学-右と左からみた生命の世界」   17 Nov 2017   同仁化学研究所
阻害剤開発を目指したD-アミノ酸坂酵素阻害作用分子の解析
Kiyoshi Fukui
第450回ビタミンB研究協議会   28 Oct 2017   ビタミンB研究委員会
N-Sアシル基転移を基盤としたタンパク質ラベル化法を用いたD-アミノ酸酸化酵素阻害剤の結合サイト解明研究
Taiki Kohiki, Yusuke Kato, Yusuke Nishikawa, Kazuko YORITA, Ikuko Sagawa, Masaya Denda, Tsubasa Inokuma, Akira Shigenaga, Kiyoshi Fukui, Akira Otaka
第56回日本薬学会・日本薬剤師会・日本大学病院薬剤師会中国四国支部学術大会   21 Oct 2017   
D-アミノ酸酸化酵素の相互作用分子に関する計算科学的解析
Yusuke Kato, Kiyoshi Fukui
Japanese Bioimaging Society Symposium   17 Sep 2017   
抗インフルエンザ薬の効果が不良な小児のノイラミニダーゼ(NA)解析
伊藤 吹夕, Yusuke Kato, ?橋 和浩, 菅又 龍一, 鈴木 章一, 山本 友子, 河内 正治, Kiyoshi Fukui, 三牧 正和, Kazuo Suzuki
第26回 日本バイオイメージング学会学術集会   16 Sep 2017   
Translational enzymology on D-amino acid metabolism [Invited]
Kiyoshi Fukui, Hong Diem Tran, Hirofumi Sogabe, SooHyeon Kim, Trinh Thanh Thi Huong, Anh Tuan Pham, Yuji Shishido, Kazuko YORITA, Yusuke Kato
The 3rd International Conference of D-Amino Acid Research   11 Jul 2017   D-アミノ酸学会
Regulation of D-amino acid oxidase expression and metabolism in mammalian cells
Hirofumi Sogabe, Yuji Shishido, SooHyeon Kim, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
The 3rd International Conference of D-Amino Acid Research   10 Jul 2017   D-アミノ酸学会
Screening of the effectors for human D-amino acid oxidase and the analyses of structure-activity relationships
Kazuko YORITA, Sumire Kurosawa, Yuri Yoshida, Yoshiki Kashiwada, Shigeki Sano, Akira Otaka, Kiyoshi Fukui
The 19th triennial International Symposium on Flavins and Flavoproteins   3 Jul 2017   International Symposium on Flavins and Flavoproteins
哺乳動物細胞におけるD-アミノ酸酸化酵素タンパク質の代謝経路の解析
Hirofumi Sogabe, Yuji Shishido, Soo Hyeon Kim, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
日本ビタミン学会第69回大会   10 Jun 2017   The Vitamin Society of Japan
Regulation of D-amino acid oxidase expression in mammalian cells
Hirofumi Sogabe, Yuji Shishido, Kiyoshi Fukui
11th International Symposium of The Institute Network Frontiers in Biomedical Sciences   27 Jan 2017   International Symposium of the Institute Network
新規NF-κB制御分子ヌクリングはインスリンの発現制御に関与している
Wenling Lin, Tuan Anh Pham, Kiyoshi Fukui, Takashi Sakai
第39回日本分子生物学会年会   2 Dec 2016   The Molecular Biology Society of Japan
Structure and function prediction of the G72 protein
Yusuke Kato, Kiyoshi Fukui
第54回日本生物物理学会年会   27 Nov 2016   
D-システインからの硫化水素産生
渋谷 典広, 小池 伸, 田中 真紀子, 湯浅 磨里, 木村 由佳, 小笠原 祐樹, Kiyoshi Fukui, 永原 則之, 木村 英雄
第89回日本生化学会大会   27 Sep 2016   The Japanese Biochemical Society
D-アミノ酸酸化酵素の相互作用分子に関する計算科学的解析
Yusuke Kato, 早田 海渡, Kiyoshi Fukui
第89回日本生化学会大会   26 Sep 2016   The Japanese Biochemical Society
グリア細胞におけるヒトD-アミノ酸酸化酵素遺伝子の発現誘導機構の解明
Yuji Shishido, Huong Thi Thanh Trinh, Soo Hyeong Kim, Hirofumi Sogabe, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第89回日本生化学会大会   26 Sep 2016   The Japanese Biochemical Society
ヒトD-アミノ酸酸化酵素遺伝子の発現調節機構と炎症反応
Yuji Shishido, Yuta Isomura, Hiroya Matsuda, Huong Thi Thanh Trinh, Soo Hyeong Kim, Hirofumi Sogabe, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第12回D-アミノ酸学会学術講演会   15 Sep 2016   D-アミノ酸学会
トリインフルエンザ劇症化における NS1 ダイマーの分子機構
Yusuke Kato, Kiyoshi Fukui, Kazuo Suzuki
第25回日本バイオイメージング学会学術集会   5 Sep 2016   日本バイオイメージング学会
Medical aspects and chiral science of amino acid metabolism: regulation of human D-amino acid oxidase gene expression and implication for translation to neuropsychiatric disorders [Invited]
Kiyoshi Fukui, Hirofumi Sogabe, Soo Hyeon Kim, Hung Thi Thanh Trinh, Tuan Anh Pham, Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Yusuke Kato
The Fifth International Conference on Cofactors and Active Enzyme Molecule 2016   5 Sep 2016   International Conference on Cofactors
A novel apoptosis associated protein, Nucling Controls Mammary Gland Involution by Regulating NF-B and STAT3: Implication for the pathogenesis of breast cancer [Invited]
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
Inaugural Symposium Biochemistry: Towards Academic Excellence   22 Jun 2016   College of Biochemists Sri Lanka
ヒトD-アミノ酸酸化酵素のエフェクター探索と構造活性相関
Kazuko YORITA, Sumire Kurosawa, Yuuri Yoshida, Akira Otaka, Yoshiki Kashiwada, Shigeki Sano, Noriaki Minakawa, Kiyoshi Fukui
日本ビタミン学会第68回大会   18 Jun 2016   The Vitamin Society of Japan
D-アミノ酸酸化酵素遺伝子の発現調節機構の解析による統合失調症胎児期起源仮説の考察
Kiyoshi Fukui, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Soo Hyeon Kim, Hirofumi Sogabe, Kazuko YORITA, Yusuke Kato
第444回ビタミンB研究協議会   16 Jun 2016   ビタミンB研究委員会
低栄養ストレスによる D-アミノ酸酸化酵素タンパク質の動的変化
Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第57回日本生化学会 中国四国支部例会   28 May 2016   The Japanese Biochemical Society, Chu-Shikoku Branch
Regulation of gene expression of mouse D-amino acid oxidase
Huong Thi Thanh Trinh, Yuji Shishido, Diem Hong Tran, Hirofumi Sogabe, Soo Hyeon Kim, Kiyoshi Fukui
第57回日本生化学会 中国四国支部例会   28 May 2016   The Japanese Biochemical Society, Chu-Shikoku Branch
In situ click chemistryを利用したD-アミノ酸酸化酵素阻害剤の探索研究
Shohei Toguchi, Tomoyasu Hirose, Kazuko YORITA, Kiyoshi Fukui, Barry K Sharpless, Satoshi ?mura, Toshiaki Sunazuka
日本薬学会第136年会   29 Mar 2016   The Pharmaceutical Society of Japan
Nucling, a Novel Apoptosis-associated Protein, Controls Mammary Gland Involution by Regulating NF-B and STAT3 [Invited]
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
1st International Symposium on Molecular Medicine in Tokushima University   16 Dec 2015   Tokushima University
生理活性物質硫化水素の産生経路
渋谷 典広, 小池 伸, 田中 真紀子, 湯浅 磨里, 木村 由佳, 小笠原 裕樹, Kiyoshi Fukui, 永原 則之, 木村 英雄
第38回日本分子生物学会年会,第88回日本生化学会大会 合同大会   4 Dec 2015   The Japanese Biochemical Society
アミノ酸代謝のキラルサイエンスと統合失調症病態システム酵素学
Kiyoshi Fukui, Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Kazuko YORITA, Yusuke Kato
第38回日本分子生物学会年会,第88回日本生化学会大会 合同大会   3 Dec 2015   The Japanese Biochemical Society
ヒト細胞におけるD-アミノ酸酸化酵素遺伝子の発現調節機構
Yuji Shishido, Diem Hong Tran, Soo Hyeon Kim, Huong Thi Thanh Trinh, Hirofumi Sogabe, Takanaga Ako, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第38回日本分子生物学会年会,第88回日本生化学会大会 合同大会   3 Dec 2015   The Japanese Biochemical Society
Chiral Science and Pathophysiology of Amino Acid Metabolism: regulation of human D-amino acid oxidase gene expression and implication for human psychiatric disorders. [Invited]
Kiyoshi Fukui, Diem Hong Tran, Huy Van Dang, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Yuji Shishido, Kazuko YORITA, Yusuke Kato, Takashi Sakai
14th FAOBMB Congress and 84th Annual Meeting of SBC (I)   30 Nov 2015   Federation of Asian and Oceanian Biochemists and Molecular Biologists
D-アミノ酸酸化酵素調節因子 G72 のドメインモデリング
Yusuke Kato, Kiyoshi Fukui
第24回日本バイオイメージング学会学術集会   29 Sep 2015   
In Situ Click Chemistryを利用したD-アミノ酸酸化酵素阻害剤の探索研究
Shohei Toguchi, Tomoyasu Hirose, Kazuko YORITA, Kiyoshi Fukui, Satoshi ?mura, Toshiaki Sunazuka
AKPS集会第9回北里化学シンポジウム   26 Sep 2015   Kitasato University
Search for the regulation of human D-amino acid oxidase gene, a potential risk factor of schizophrenia
Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 2nd GENE AND IMMUNOTHERAPY CONFERENCE in VIETNAM   25 Sep 2015   Vietnam National University, Ho Chi Minh City
Nucling, a novel apoptosis-associated protein, controls postlactational involution of mammary gland through regulation of NF-B and STAT3 [Invited]
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
The 2nd GENE AND IMMUNOTHERAPY CONFERENCE in VIETNAM   25 Sep 2015   Vietnam National University, Ho Chi Minh City
哺乳動物における D-アミノ酸酸化酵素遺伝子の発現誘導機構の解析
Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Soo Hyoen Kim, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第 11 回 D-アミノ酸学会学術講演会   25 Aug 2015   D-アミノ酸学会
Nucling, an apoptosis-associated novel protein, controls mammary gland involution through regulation of NF-B and STAT3
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
The 10th International Symposium of the Institute Network   24 Jul 2015   International Symposium of the Institute Network
In silico approach to elucidate the regulatory mechanism of D-amino acid oxidase
Yusuke Kato, Kiyoshi Fukui
The 10th International Symposium of the Institute Network   23 Jul 2015   International Symposium of the Institute Network
Chiral science of amino acid metabolism and implication to pathophysiology of schizophrenia [Invited]
Kiyoshi Fukui, Diem Hong Tran, Huy Van Dang, Huong Thi Thanh Trinh, Tuan Anh Pham, Hirofumi Sogabe, Soo Hyeon Kim, Takanaga Ako, Yuji Shishido, Kazuko YORITA, Yusuke Kato, Takashi Sakai
40th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology   10 Jun 2015   Federation of Asian and Oceanian Biochemists and Molecular Biologists
ヒトD-アミノ酸酸化酵素遺伝子の発現調節機構:2つのプロモーター領域の同定とその調節
Diem Hong Tran, Yuji Shishido, Seongpil Chung, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
日本ビタミン学会第67回大会   6 Jun 2015   The Vitamin Society of Japan
腎臓近位尿細管様細胞におけるD-アミノ酸酸化酵素の発現調節機構の解析
Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Kazuko YORITA, Yusuke Kato, Kiyoshi Fukui
第56回日本生化学会 中国四国支部例会   30 May 2015   The Japanese Biochemical Society, Chu-Shikoku Branch
ヒト由来D-アミノ酸酸化酵素のエフェクター探索のためのハイスループットクリーニングと構造機能相関
Kazuko YORITA, Sumire Kurosawa, Yuji Shishido, Shigeki Sano, Yoshiki Kashiwada, Noriaki Minakawa, Kiyoshi Fukui
第56回日本生化学会 中国四国支部例会   30 May 2015   The Japanese Biochemical Society, Chu-Shikoku Branch
Nucling an apoptosis-associated novel protein, controls the postlactational involution of mammary gland through regulation of NF-B and STAT3
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
The 87th Annual Meeting of the Japanese Biochemical Society   18 Oct 2014   The Japanese Biochemical Society
D-システインからの生理活性物質硫化水素の生産
渋谷 典広, 小池 伸, 田中 真紀子, 湯浅 磨里, 木村 由佳, 小笠原 裕樹, Kiyoshi Fukui, 永原 則之, 木村 英雄
The 87th Annual Meeting of the Japanese Biochemical Society   18 Oct 2014   The Japanese Biochemical Society
哺乳動物の中枢神経系におけるDーアミノ酸酸化酵素遺伝子発現誘導機構
Yuji Shishido, Kana Morimoto, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Takanaga Ako, Kazuko YORITA, Kiyoshi Fukui
The 87th Annual Meeting of the Japanese Biochemical Society   12 Oct 2014   The Japanese Biochemical Society
D-AMINO ACID METABOLISM IN HEALTH AND DISEASES: PATHOPHYSIOLOGICAL BASES FOR SCHIZOPHRENIA AND CANCER GENE THERAPY [Invited]
Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Hirofumi Sogabe, Takanaga Ako, Yuji Shishido, Kazuko YORITA, Takashi Sakai
The 2nd International Conference of D-Amino Acid Research   5 Sep 2014   D-アミノ酸学会
Communication Know-how course: A practical approach to improving professional communication skills in graduate and post-graduate education
Bukasa Kalubi, Omar Maningo Rodis, Masashi Akaike, Kiyoshi Fukui
17th JASMEE Academic Meeting   20 Jul 2014   
Identification of promoter region of human D-amino acid oxidase (hDAO) gene and its interacting proteins - Search for the regulation of hDAO expression
Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 9th International Symposium of the Institute Network   19 Jun 2014   International Symposium of the Institute Network
Induction and regulation of gene expression of D-amino acid oxidase in glial and kidney cells
Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
日本ビタミン学会第66回大会   14 Jun 2014   The Vitamin Society of Japan
新規アポトーシス誘導因子ヌクリングのホモシステイン代謝系及び神経精神疾患への関与の検討
Takashi Sakai, Yukiya Sako, Yuki Honjo, Kota Nakajima, Huy Van Dang, Tuan Anh Pham, Yuji Shishido, Kazuko YORITA, Kiyoshi Fukui
日本ビタミン学会第66回大会   13 Jun 2014   The Vitamin Society of Japan
中枢神経系におけるD-アミノ酸酸化酵素遺伝子の発現誘導機構の解析
Kana Morimoto, Yuji Shishido, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA, Kiyoshi Fukui
第55回日生化学会 中国四国支部例会   7 Jun 2014   The Japanese Biochemical Society, Chu-Shikoku Branch
Loss of Nucling promotes delayed mammary gland involution through suppression of NF-B and STAT3
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
第55回日生化学会 中国四国支部例会   6 Jun 2014   The Japanese Biochemical Society, Chu-Shikoku Branch
Pathophysiological Basis of D-Amino Acid Metabolizing System in Brain for Susceptibility to Schizophrenia [Invited]
Kiyoshi Fukui
FAOBMB/HKSBMB Mini-Symposium 2014 Perspectives and Challenges in Biochemistry and Molecular Biology   6 Jun 2014   Federation of Asian and Oceanian Biochemists and Molecular Biologists
ビタミン B 群が担う脳内 D-アミノ酸代謝システムの疾患酵素学研究 [Invited]
Kiyoshi Fukui
ビタミンB研究委員会平成25年度シンポジウム   31 Jan 2014   ビタミンB研究委員会
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells
Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 86th Annual Meeting of the Japanese Biochemical Society   12 Sep 2013   The Japanese Biochemical Society
Delayed mammary gland involution in Nucling-KO mice
Huy Van Dang, Takashi Sakai, Tuan Anh Pham, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Kiyoshi Fukui
The 86th Annual Meeting of the Japanese Biochemical Society   12 Sep 2013   The Japanese Biochemical Society
Analysis of the regulatory mechanism of mammalian D-amino acid oxidase gene expression [Invited]
Yuji Shishido, Kana Morimoto, Diem Hong Tran, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA, Kiyoshi Fukui
The 86th Annual Meeting of the Japanese Biochemical Society   12 Sep 2013   The Japanese Biochemical Society
Nonalcoholic fatty liver disease (NAFLD) and altered insulin expression in mice lacking Nucling
Takashi Sakai, Yukiya Sako, Huy Van Dang, Tuan Anh Pham, Kiyoshi Fukui
The 86th Annual Meeting of the Japanese Biochemical Society   12 Sep 2013   The Japanese Biochemical Society
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells
Diem Hong Tran, Yuji Shishido, Huong Thi Thanh Trinh, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
第9回 D-アミノ酸研究会学術講演会   5 Sep 2013   D-アミノ酸研究会
遺伝子発現調節から探るグリア・ニューロン連関の病態システム酵素学
Yuji Shishido, Diem Hong Tran, Kana Morimoto, Huong Thi Thanh Trinh, Hirofumi Sogabe, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
第433回ビタミンB研究協議会   30 Aug 2013   ビタミンB研究委員会
Induction and regulation of gene expression of in LLC-PK1 cells
Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
第54回日本生化学会 中国四国支部例会   1 Jun 2013   The Japanese Biochemical Society, Chu-Shikoku Branch
D-アミノ酸代謝システムをターゲットとした疾患酵素学研究 [Invited]
Kiyoshi Fukui
第65回日本ビタミン学会大会   18 May 2013   The Vitamin Society of Japan
Medical Aspects of D-Amino Acid Metabolism: Molecular Target for Cancer Gene Therapy and Schizophrenia [Invited]
Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Takashi Sakai
FAOBMB Mini-Symposium Molecular Bases for Medical and Pharmaceutical Sciences   6 Apr 2013   Federation of Asian and Oceanian Biochemists and Molecular Biologists
Medical Aspects of D-Amino Acid Metabolism: Molecular Target for Cancer Gene Therapy and Schizophrenia [Invited]
Kiyoshi Fukui, Yoshiteru Urai, Hwan Ki Park, Tomoya Kawazoe, Sanae Iwana, Koji Ono, Rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Takashi Sakai
The 1st GENE AND IMMUNOTHERAPY CONFERENCE   21 Mar 2013   Vietnam National University, Ho Chi Minh City
Oxidative Stress-Energy Deplation Therapy as a New Treatment Modality for Glioma
Kiyoshi Fukui, Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran, Takashi Sakai
Miami 2013 Winter Symposium: The Molecular Basis of Metabolism and Nutrition   11 Feb 2013   Univeristy of Miami
Nucling, a novel protein associated with NF-kappaB, Regulates endotoxin-induced apoptosis in vivo
Sun Mi Kim, Takashi Sakai, Nam Hoang Tran, Sako Yukiya, Huy Van Dang, Kiyoshi Fukui
The 85th Annual Meeting of the Japanese Biochemical Society   16 Dec 2012   The Japanese Biochemical Society
Another pathway to produce H2S in the brain
Shibuya Norihiro, Mari Ishigami, Makiko Tanaka, Yuka Kimura, Yuki Ogasawara, Kiyoshi Fukui, Hideo Kimura
The 85th Annual Meeting of the Japanese Biochemical Society   16 Dec 2012   The Japanese Biochemical Society
四塩化炭素中毒におけるKupffer細胞による肝炎拡大機構
Kaori Kiso, 上野 聡子, 福田 麻菜, 市 育代, 小林 慧子, Takashi Sakai, Kiyoshi Fukui, 小城 勝相
The 85th Annual Meeting of the Japanese Biochemical Society   16 Dec 2012   The Japanese Biochemical Society
Regulation of gene expression of D-amino acid oxidase in glial cells
Yuji Shishido, Diem Hong Tran, Kana Morimoto, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 85th Annual Meeting of the Japanese Biochemical Society   15 Dec 2012   The Japanese Biochemical Society
Induction and regulation of gene expression of D-amino acid oxidase in LLC-PK1 cells
Diem Hong Tran, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 85th Annual Meeting of the Japanese Biochemical Society   15 Dec 2012   The Japanese Biochemical Society
新規NF-κB制御分子ヌクリングは非アルコール性脂肪肝及び糖尿病発症抑制に重要である
Takashi Sakai, Yukiya Sako, Seongpil Chung, Sun Mi Kim, Huy Van Dang, Rieko Nakata, Kiyoshi Fukui
第16回日本心血管内分泌代謝学会学術総会   23 Nov 2012   The Society of Cardiovascular Endocrinology and Metabolism
統合失調症の疾患酵素学:D-アミノ酸酸化酵素の活性制御による新規治療戦略 [Invited]
Kiyoshi Fukui
第64回シグナル伝達医学グローバルCOE学術講演会   9 Aug 2012   「次世代シグナル伝達医学の教育研究国際拠点」 シグナル伝達医学グロ-バルCOE事務局
D-アミノ酸酸化酵素関連遺伝子の発現に関するマイクロアレイ並びにプロテオミクス解析
Seongpil Chung, Yuji Shishido, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
日本ビタミン学会第64回大会   23 Jun 2012   The Vitamin Society of Japan
Oxidative stress-energy depletion therapy as a new treatment modality for cancer
Kiyoshi Fukui, Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Diem Hong Tran, Takashi Sakai
日本ビタミン学会第64回大会   23 Jun 2012   The Vitamin Society of Japan
ホモシステイン代謝系における新規NF-κB制御因子ヌクリングの関与
Yukiya Sako, Seongpil Chung, Sun Mi Kim, Huy Van Dang, Nakata Rieko, Takashi Sakai, Kiyoshi Fukui
日本ビタミン学会第64回大会   23 Jun 2012   The Vitamin Society of Japan
新規 NF-kB 制御分子ヌクリングの炎症性病態への関与についての検討
Mi Sun Kim, Takashi Sakai, Huy Van Dang, Yukiya Sako, Kiyoshi Fukui
第53回 日本生化学会中国・四国支部例会・シンポジウム   18 May 2012   The Japanese Biochemical Society, Chu-Shikoku Branch
アストログリア細胞におけるD-セリン代謝産物ヒドロキシピルビン酸の細胞死誘導活性
Seongpil Chung, Diem Hong Tran, Kazuko YORITA, Yuji Shishido, Takashi Sakai, Kiyoshi Fukui
第53回日本生化学会 中国・四国支部例会   18 May 2012   The Japanese Biochemical Society, Chu-Shikoku Branch
Another Pathway to produce hydrogen sulfide in the brain
Norihiro Shibuya, Mari Ishigami, Mariko Tanaka, Yuka Kimura, Yuki Ogasawara, Kiyoshi Fukui, Hideo Kimura
第85回日本薬理学会年会   15 Mar 2012   The Japanese Pharmacological Society
酸化ストレス誘導系と解糖系を分子標的としたD-アミノ酸酸化酵素遺伝子による グリオーマ治療法
Kiyoshi Fukui
第427回ビタミンB研究協議会   4 Feb 2012   ビタミンB研究委員会
D-アミノ酸代謝システムの活性制御による新規精神神経疾患治療薬の開発戦略 [Invited]
Kiyoshi Fukui
日本応用酵素協会第37回研究発表会   14 Nov 2011   Japan Foundation for Applied Enzymology
D―アミノ酸酸化酵素を用いたグリオーマの遺伝子治療戦略
Kiyoshi Fukui
第426回ビタミンB研究協議会   5 Nov 2011   ビタミンB研究委員会
D-アミノ酸代謝酵素システムの活性制御による新規精神神経疾患治療薬の開発戦略 [Invited]
Kiyoshi Fukui
第3回共同利用・共同研究「酵素学研究拠点」シンポジウム   3 Oct 2011   Institute for Enzyme Research
D-アミノ酸代謝システムの活性制御による新規精神神経疾患治療戦略
Kiyoshi Fukui, rabab Mohamed Abou El-Magd, Seongpil Chung, Salah Mohamed El-Sayed, Diem Hong Tran, Kumiko Shinohara, Yuji Shishido, Kazuko YORITA, Takashi Sakai
The 84th Annual Meeting of the Japanese Biochemical Society   24 Sep 2011   The Japanese Biochemical Society
新規アポトーシス/NF-κB制御分子ヌクリングの機能解析
Takashi Sakai, Sun Mi Kim, Nam Hoang Tran, Kiyoshi Fukui
The 84th Annual Meeting of the Japanese Biochemical Society   23 Sep 2011   The Japanese Biochemical Society
ヒトD-アミノ酸酸化酵素のグリア細胞内における機能解析
Yuji Shishido, Ying Song, Kumiko Shinohara, Diem Hong Tran, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
The 84th Annual Meeting of the Japanese Biochemical Society   23 Sep 2011   The Japanese Biochemical Society
Combination of oxidative stress and energy depletion induced significant glioma cell death
Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Kazuko YORITA, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui
The 84th Annual Meeting of the Japanese Biochemical Society   23 Sep 2011   The Japanese Biochemical Society
アストログリア細胞内の D-アミノ酸酸化酵素により D-セリンから産生されるヒ ドロキシピルビン酸の細胞死誘導活性
Seongpil Chung, Ying Song, Hwan Ki Park, Yuji Shishido, Kazuko YORITA, Takashi Sakai, Kiyoshi Fukui
第7回 D-アミノ酸研究会学術講演会   10 Sep 2011   D-アミノ酸研究会
D-アミノ酸酸化酵素の遺伝子導入により,グリオーマ細胞では,3-ブロモピル ビン酸の解糖系への阻害作用が増強される
Salah Mohamed El-Sayed, Rabab Mohamed Abou El-Magd, Yuji Shishido, Seongpil Chung, Takashi Sakai, Hiroyoshi Watanabe, Shoji Kagami, Kiyoshi Fukui
第7回 D-アミノ酸研究会学術講演会   10 Sep 2011   D-アミノ酸研究会
Modulation of D-amino acid oxidase activity as a novel strategy for the treatment of psychiatric disorders [Invited]
Kiyoshi Fukui, Tomoya Kawazoe, Sanae Iwana, Rabab Mohamed Abou El-Magd, Koji Ono, Seongpil Chung, Salah Mohamed El-Sayed, Kumiko Shinohara, Diem Hong Tran, Yuji Shishido, Kazuko YORITA, Takashi Sakai
Function and dysfunction of D-amino acids in the central nervous system   10 Sep 2011   The Center for Brain Integration Research

Works

 
Molecular Enzymology on the Structure and Function of D-Amino Acid Oxidase
2003

Research Grants & Projects

 
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2018 - Mar 2023    Investigator(s): 加藤 有介
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
Project Year: Apr 2013 - Mar 2016    Investigator(s): SAKAI TAKASHI
Japan Science and Technology Agency (JST): CORE RESEARCH FOR EVOLUTIONARY SCIENCE AND TECHNOLOGY (CREST)
Project Year: Oct 2009 - Mar 2015    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 2010 - Mar 2013    Investigator(s): SAKAI Takashi
Molecular Cell Biology and Pathophysiology on Apoptosis
Japan Society for the Promotion of Science: Joint Research Project --For Japan-Korea Joint Research Project--
Project Year: Apr 2008 - Mar 2010    Investigator(s): FUKUI Kiyoshi
JST: A-STEP
Project Year: Apr 2008 - Mar 2009    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 2007 - Mar 2009    Investigator(s): SAKAI Sakai
JST: 
Project Year: Apr 2006 - Mar 2007    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 2005 - Mar 2007    Investigator(s): 福井 清
Ministry of Health, Labour and Welfare: 
Project Year: Apr 2004 - Mar 2007    Investigator(s): NISHIKAWA Toru
Grants-in-Aid for Scientific Research
Project Year: Apr 2004 - Mar 2006    Investigator(s): 冨田 優美子
Japan Society for the Promotion of Science: Joint Research Project --For Japan-Korea Joint Research Project--
Project Year: Apr 2004 - Mar 2006    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 2002 - Mar 2004    Investigator(s): 村上 理一
Grants-in-Aid for Scientific Research
Project Year: Apr 2001 - Mar 2003    Investigator(s): FUKUI Kiyoshi
Studies on the Function and Signal Transduction of Novel Apoptosis Regulatory Factor.
Grant-in-Aid for Scientific Research
Project Year: 2003   
Grants-in-Aid for Scientific Research
Project Year: Apr 2000 - Mar 2001    Investigator(s): 江崎 信芳
Grants-in-Aid for Scientific Research
Project Year: Apr 1997 - Mar 2000    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 1998 - Mar 1999    Investigator(s): 福井 清
Grants-in-Aid for Scientific Research
Project Year: Apr 1997 - Mar 1999    Investigator(s): KANAYAMA Hiro-omi
Grants-in-Aid for Scientific Research
Project Year: Apr 1997 - Mar 1998    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 1996 - Mar 1997    Investigator(s): FUKUI Kiyoshi
Grants-in-Aid for Scientific Research
Project Year: Apr 1995 - Mar 1996    Investigator(s): 福井 清
Grants-in-Aid for Scientific Research
Project Year: Apr 1993 - Mar 1995    Investigator(s): FUKUI Kiyoshi
Molecular Biological Studies on the Function and Signal Transduction of Novel Cardiovascular Regulatory Factors.
Grant-in-Aid for Scientific Research
Project Year: 1995   
Structure and Pathophysiological Significance of D-amino Acid Oxidase.
Grant-in-Aid for Scientific Research
Project Year: 1995   
Grants-in-Aid for Scientific Research
Project Year: Apr 1988 - Mar 1991    Investigator(s): MIYAKE Yoshihiro
Grants-in-Aid for Scientific Research
Project Year: Apr 1986 - Mar 1988    Investigator(s): MIYAKE Yoshihiro
Development of Neuromodulatory Drugs

Patents

 
特許3985131 : NEW APOPTOSIS-INDUCING PROTEIN AND GENE ENCODING THE SAME
FUKUI Kiyoshi, SAKAI Takashi
A novel Apoptosis-inducing Protein and Its Encoding Gene
PAT. No. 3985131

Social Contribution

 
The board of Directors of Japan Foundation for Applied Enzymology
[Advisor, Organizing Member]  Japan Foundation for Applied Enzymology  1 Jun 2013 - Today
The board of Directors of SHOSHISHA
[Advisor, Organizing Member]  SHOSHISHA Foundation  1 Jun 2018 - 31 May 2020