法喜ゆう子 (Yuko Hoki) - マイポータル

基本情報

所属: 国立研究開発法人量子科学技術研究開発機構放射線医学総合研究所放射線障害治療研究部幹細胞研究グループ研究員

通称等の別名: 藤森ゆう子
J-GLOBAL ID: 200901095503705361
researchmap会員ID: 0000035835

研究分野

ライフサイエンス / 細胞生物学 /

論文

iPS cell generation-associated point mutations include many C > T substitutions via different cytosine modification mechanisms.

Ryoko Araki, Tomo Suga, Yuko Hoki, Kaori Imadome, Misato Sunayama, Satoshi Kamimura, Mayumi Fujita, Masumi Abe

Nature communications 15(1) 4946-4946 2024年6月11日
Insertion/deletion and microsatellite alteration profiles in induced pluripotent stem cells.

Satoshi Kamimura, Tomo Suga, Yuko Hoki, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Miki Nakamura, Ryoko Araki, Masumi Abe

Stem cell reports 16(10) 2503-2519 2021年10月12日
Genetic aberrations in iPSCs are introduced by a transient G1/S cell cycle checkpoint deficiency.

Ryoko Araki, Yuko Hoki, Tomo Suga, Chizuka Obara, Misato Sunayama, Kaori Imadome, Mayumi Fujita, Satoshi Kamimura, Miki Nakamura, Sayaka Wakayama …

Nature communications 11(1) 197-197 2020年1月10日
Low- and High-LET Ionizing Radiation Induces Delayed Homologous Recombination that Persists for Two Weeks before Resolving.

Christopher P Allen, Hirokazu Hirakawa, Nakako Izumi Nakajima, Sophia Moore, Jingyi Nie, Neelam Sharma, Mayumi Sugiura, Yuko Hoki, Ryoko Araki, Masumi Abe …

Radiation research 188(1) 82-93 2017年7月
The Number of Point Mutations in Induced Pluripotent Stem Cells and Nuclear Transfer Embryonic Stem Cells Depends on the Method and Somatic Cell Type Used for Their Generation.

Ryoko Araki, Eiji Mizutani, Yuko Hoki, Misato Sunayama, Sayaka Wakayama, Hiroaki Nagatomo, Yasuji Kasama, Miki Nakamura, Teruhiko Wakayama, Masumi Abe

Stem cells (Dayton, Ohio) 35(5) 1189-1196 2017年5月
Induced pluripotent stem cell generation-associated point mutations arise during the initial stages of the conversion of these cells.

Mayumi Sugiura, Yasuji Kasama, Ryoko Araki, Yuko Hoki, Misato Sunayama, Masahiro Uda, Miki Nakamura, Shunsuke Ando, Masumi Abe

Stem cell reports 2(1) 52-63 2014年1月14日
Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells.

Ryoko Araki, Masahiro Uda, Yuko Hoki, Misato Sunayama, Miki Nakamura, Shunsuke Ando, Mayumi Sugiura, Hisashi Ideno, Akemi Shimada, Akira Nifuji …

Nature 494(7435) 100-4 2013年2月7日
Crucial role of c-Myc in the generation of induced pluripotent stem cells.

Ryoko Araki, Yuko Hoki, Masahiro Uda, Miki Nakamura, Yuko Jincho, Chihiro Tamura, Misato Sunayama, Shunsuke Ando, Mayumi Sugiura, Mitsuaki A Yoshida …

Stem cells (Dayton, Ohio) 29(9) 1362-70 2011年9月
Generation of genome integration-free induced pluripotent stem cells from fibroblasts of C57BL/6 mice without c-Myc transduction.

Yuko Jincho, Ryoko Araki, Yuko Hoki, Chihiro Tamura, Miki Nakamura, Shunsuke Ando, Yasuji Kasama, Masumi Abe

The Journal of biological chemistry 285(34) 26384-9 2010年8月20日
Conversion of ancestral fibroblasts to induced pluripotent stem cells.

Ryoko Araki, Yuko Jincho, Yuko Hoki, Miki Nakamura, Chihiro Tamura, Shunsuke Ando, Yasuji Kasama, Masumi Abe

Stem cells (Dayton, Ohio) 28(2) 213-20 2010年2月
A proximal conserved repeat in the Xist gene is essential as a genomic element for X-inactivation in mouse

Yuko Hoki, Naomi Kimura, Minako Kanbayashi, Yuko Amakawa, Tatsuya Ohhata, Hiroyuki Sasaki, Takashi Sado

DEVELOPMENT 136(1) 139-146 2009年1月査読有り
Crucial role of antisense transcription across the Xist promoter in Tsix-mediated Xist chromatin modification

Tatsuya Ohhata, Yuko Hoki, Hiroyuki Sasaki, Takashi Sado

DEVELOPMENT 135(2) 227-235 2008年1月査読有り
Effect of Atm disruption on spontaneously arising and radiation-induced deletion mutations in mouse liver.

Ikuko Furuno-Fukushi, Ken-ichi Masumura, Takeshi Furuse, Yuko Noda, Masahiko Takahagi, Toshiyuki Saito, Yuko Hoki, Hiroshi Suzuki, Anthony Wynshaw-Boris, Takehiko Nohmi …

Radiation research 160(5) 549-58 2003年11月
Growth retardation and skin abnormalities of the Recql4-deficient mouse.

Yuko Hoki, Ryoko Araki, Akira Fujimori, Tatsuya Ohhata, Haruhiko Koseki, Ryutaro Fukumura, Miki Nakamura, Hirokazu Takahashi, Yuko Noda, Seiji Kito …

Human molecular genetics 12(18) 2293-9 2003年9月15日
Enhanced phosphorylation of p53 serine 18 following DNA damage in DNA-dependent protein kinase catalytic subunit-deficient cells

R Araki, R Fukumura, A Fujimori, Y Taya, Y Shiloh, A Kurimasa, S Burma, GC Li, DJ Chen, K Sato …

CANCER RESEARCH 59(15) 3543-3546 1999年8月査読有り

MISC

iPS細胞におけるマイクロサテライト異常

KAMIMURA Satoshi, SUGA Tomo, HOKI Yuko, SUNAYAMA Misato, IMADOME Kaori, FUJITA Mayumi, NAKAMURA Miki, ARAKI Ryoko, ABE Masumi

日本分子生物学会年会プログラム・要旨集(Web) 44th 2021年
ヒトiPS細胞樹立におけるゲノム変異とその機構

荒木良子, 法喜ゆう子, 菅智, 砂山美里, 今留香織, 上村悟氏, 中村美樹, 藤田真由美, 安倍真澄

日本毒性学会学術年会 48.1 S3-3 2021年
Induced pluripotent stem cell generation-associated point mutations.

Araki R, Sugiura M, Hoki Y, Sunayama M, Nakamura M, Kasama Y, Abe M

Inflammation and Regeneration 35(5) 226-232 2015年招待有り