J-GLOBAL         Last updated: Feb 24, 2017 at 14:43
The University of Tokyo
Institute of Molecular and Cellular Biosciences Laboratory of Developmental Biology
Job title
Associate Professor
Ph.D(The University of Tokyo)

Research Areas


Awards & Honors

1989 Alexandrine and Alexander L.Sinsheimer Scholar Award


A plant DNA-binding protein increases the number of active preinitation complexes in a human in vitro transcription system
Genes. Dev. 4, 1899-1909, 1990   
Activation of the adenovirus EIIa late promoter by a single-point mutation which enhances binding of transcription factor IID
J. Biol. Chem. 263, 12596-12601, 1988   
Analysis of the role of TFIIE in basal transcription and TFIIH-mediated carboxy-terminal domain phosphorylation through structure-function studies of TFIIE-alpha
Mol. Cell. Biol, 15, 4856-4866, 1995   
Analysis of the stimulatory factor of RNA polymerase II in the initiation and elongation complex
J. Biol. Chem. 259, 608-611, 1984   
Analysis pf structure-function relationships of yrast TATA box binding factor TFIID
Cell. 61, 1171-1178, 1990   
Cloning of the Schizosaccharomuces pombe TFIID gene reveals a strong conservation of functional domains present in Saccharomyce cerevisiae TFIID
Genes. Dev. 4, 1141-1148, 1990   
Direct binding of yeast transcription factor to the ribosomal protein L32 (rpL32) TATA-less promoter sequence
FEBS Lett. 1326, 163-166, 993   
Direct mapping of the human TATA box-binding protein gene to 6q27 by fluorescence in situ hybridization
Jpn. J. Human Genet, 39, 421-425, 1994   
Enhancement of the frequency of initiation by a stimulatory protein of RNA polymerase II
J. Biochem. 96, 1859-1865, 1984   
Factors involved in specific transcription by mammalian RNA polymerase II: Functional analysis of initiation factors IIA and IID and identification of a new factor operating at sequences downstream of the initiation site
J. Biol. Chem. 262, 3322-3330, 1987   
Factors involved in specific transcription by mammalian RNA polymerase II: Purification, genetic specification, and TATA box-promotor interactions of TFIID
Mol. Cell. Biol8, 4028-4040, 1989   
Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity
Nature, 1363, 744-747, 1993   
Genetic and biochemical analyses of yeast TATA-binding protein mutants
J. Biol. Chem. 268, 5005-5013, 1993   
Identification of TFIID components required for transcriptional activation by upstream stimulatory factor
J. Biol. Chem. 268, 17554-17558, 1993   
Identification of subunits of RNA polymerase II from ascites tumor cells
J. Biochem. 93, 1523-1530, 1983   
Identification of the DNA binding subunits of RNA polymerase II from ascites tumor cells
J. Biochem. 94, 1761-1767, 1983   
Interaction of TFIID in the minor groove of the TATA element
Cell. 67, 1241-1250   
Isolation and initial characterization of GBF;a novel DNA-binding zinc finger protein that binds to the GC-rich binding sites of the HIV-1 promoter
J. Biochem. 124, 389-395, 1998   
Nature. 367, 484-487, 1994   
Molecukar cloning,expression,and characterization of the Drosophila 85-kilodalton TFIID subunit
Mol. Cell. Biol, 13, 7859-7863, 1993   
Nucleic Acids Res. 19, 5436, 1991   
Preferential inhibition of the activity of a stimulatory protein of eukaryotic transcription by platinum (II)complexes
Cancer Res. 43, 4338-4342, 1983   
Prefication and characterization of multiple factors that bind to the TAX-inducible enhancer within the human T-cell leukemia virus type 1 long terminal repeat
Mol. Cell. Biol. 9, 1733-1745, 1989   
Relationship between subcellular localization and structures of catalytic domains of FKBP-type PPIases
J. Biochem. 126, 879-888, 1999   
Restricted expression of a member of the transcription factor S-II family in testicular germ cells during and after meiosis
J. Biochem. 121, 598-603, 1997   
Structural relations of the three stimulatory factors of RNA polymerase II from Ehrlich ascites tumor cells
J. Biol. Chem. 260, 5739-5744, 1985   
TFIIA induces conformational changes in TFIID via interactions with the basic repeat
Mol. Cell. Biol. 20, 4363, 1992   
The conserved carboxy-terminal domain of Saccharomyces cerevisiae TFIID is sufficient to support normal cell growth
Mol. Cell. Biol. 11, 4809-4821, 1991   
The involvement of the histone fold motifs in the mutual interaction between human TAFII 80 and TAFII 22
J. Biochem. 121, 591-597, 1997   
Transcription factor(s) of Ehrlich ascites tumor cells havimg affinity to the 'TATA' box and a further upstream region of the adenovirus 2 major late gene.
Biochem. Biophys. Acta, 868, 243-248, 1986   
Transcriptionally active immediate-early protein of pseudorabies virus binds to specific sites on class II gene promoters
J. Virol. 63, 1869-1876, 1989   

Research Grants & Projects

Mechanisms of gene regulation Mechanisms of chromatin regulation