明石真言 (Makoto Akashi) - マイポータル

基本情報

所属: 国立研究開発法人量子科学技術研究開発機構執行役

学位: 医学博士

J-GLOBAL ID: 200901070932970666
researchmap会員ID: 0000040624

外部リンク: http://www.qst.go.jp/

研究キーワード

研究分野

ライフサイエンス / 血液、腫瘍内科学 /

学歴

MISC

Role of catalase in monocytic differentiation of U937 cells by TPA: hydrogen peroxide as a second messenger

T. Yamamoto, N. Sakaguchi, M. Hachiya, F. Nakayama, M. Yamakawa, M. Akashi

LEUKEMIA 23(4) 761-769 2009年4月
Ginsenoside Rd prevents and rescues rat intestinal epithelial cells from irradiation-induced apoptosis

Taiji Tamura, Xing Cui, Nagako Sakaguchi, Makoto Akashi

FOOD AND CHEMICAL TOXICOLOGY 46(9) 3080-3089 2008年9月
Involvement of Intracellular Expression of FGF12 in Radiation-Induced Apoptosis in Mast Cells

Fumiaki Nakayama, Kerstin Mueller, Akiko Hagiwara, Roland Ridi, Makoto Akashi, Viktor Meineke

JOURNAL OF RADIATION RESEARCH 49(5) 491-501 2008年9月
Hydrogen peroxide as a potential mediator of the transcriptional regulation of heparan sulphate biosynthesis in keratinocytes

Fumiaki Nakayama, Akiko Hagiwara, Tetsuo Yamamoto, Makoto Akashi

CELLULAR & MOLECULAR BIOLOGY LETTERS 13(3) 475-492 2008年9月
Metabolism and the Paradoxical Effects of Arsenic: Carcinogenesis and Anticancer

Xing Cui, Yayoi Kobayashi, Makoto Akashi, Ryuichi Okayasu

CURRENT MEDICINAL CHEMISTRY 15(22) 2293-2304 2008年9月
Pathological changes in the gastrointestinal tract of a heavily radiation-exposed worker at the Tokai-mura criticality accident

Hiroshi Igaki, Keiichi Nakagawa, Hiroshi Uozaki, Masaaki Akahane, Yoshio Hosoi, Masashi Fukayama, Kiyoshi Miyagawa, Makoto Akashi, Kuni Ohtomo, Kazuhiko Maekawa

JOURNAL OF RADIATION RESEARCH 49(1) 55-62 2008年1月
UV-irradiation induces oxidative damage to mitochondrial DNA primarily through hydrogen peroxide: Analysis of 8-oxodGuo by HPLC

Daisaku Takai, Sang-Hee Park, Yasunari Takada, Shizuko Ichinose, Masanobu Kitagawa, Makoto Akashi

FREE RADICAL RESEARCH 40(11) 1138-1148 2006年11月
Synthesis of hydrophilic macroporous chelating polymers and their versatility in the preconcentration of metals in seawater samples

M Haratake, K Yasumoto, M Ono, M Akashi, M Nakayama

ANALYTICA CHIMICA ACTA 561(1-2) 183-190 2006年3月
Radiation Damage in the Human Body - Acute Radiation Syndrome AND multiple organ failure

Akashi M, Tamura T, Tominaga T, Abe K, Hachiya M, Nakayama F

Nuclear Engineering and Technology 6(3) 231-238 2006年
Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knock evaluation on the late effect of radiation on a mouse model of HNPCC

Tokairin Y, Kakinuma S, Arai M, Nishimura M, Okamoto M, Ito E, Akashi M, Miki Y, Kawano T, Iwai T …

Int J Exp Pathol 87(2) 89-99 2006年
Neutrophils accelerate macrophage-mediated digestion of apoptotic cells in vivo as well as in vitro

Takuya Iyoda, Kisaburo Nagata, Makoto Akashi, Yoshiro Kobayashi

Journal of Immunology 175(6) 3475-3483 2005年9月15日
Neutrophils accelerate macrophage-mediated digestion of apoptotic cells in vivo as well as in vitro

T Iyoda, K Nagata, M Akashi, Y Kobayashi

JOURNAL OF IMMUNOLOGY 175(6) 3475-3483 2005年9月
Role of mitochondrial DNA in cells exposed to irradiation: Generation of reactive oxygen species (ROS) is required for G2 checkpoint upon irradiation

S Kawamura, D Takai, K Watanabe, J Hayashi, K Hayakawa, M Akashi

JOURNAL OF HEALTH SCIENCE 51(3) 385-393 2005年6月
Transient reporter RNA assay: quantification of reporter gene mRNA during immediate early response in mammalian cells based on real-time reverse transcription polymerase chain reaction

H Ishihara, Tanaka, I, F Ishihara, K Suzuki, C Yoshino, C Cheeramakara, H Wan, S Akashi

ANALYTICAL BIOCHEMISTRY 341(2) 369-371 2005年6月
Catalase regulates cell growth in HL60 human promyelocytic cells: Evidence for growth regulation by H2O2

M Hachiya, M Akashi

RADIATION RESEARCH 163(3) 271-282 2005年3月
Role of mitochondrial DNA in cells exposed to irradiation: Generation of reactive oxygen species (ROS) is required for G2 checkpoint upon irradiation

Saori Kawamura, Daisaku Takai, Keiko Watanabe, Jun-Ichi Hayashi, Kazushige Hayakawa, Makoto Akashi

Journal of Health Science 51(3) 385-393 2005年
Polyphenol (-)-epigallocatechin gallate inhibits apoptosis induced by irradiation in humian HaCaT keratinocytes

H Kondo, SH Park, K Watanabe, Y Yamamoto, M Akashi

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 316(1) 59-64 2004年3月
Endogenous production of TNF : srequired for activation of NFkB by irradiation in human monocytic cells THP-1

Cytokine 25(4), 147-154 2004年
Role of TNFα in regulation of myeloperoxidase expression in irradiated HL60 promyelocytic cells

Misao Hachiya, Yoshiaki Osawa, Makoto Akashi

Biochimica et Biophysica Acta - Molecular Cell Research 1495(3) 237-249 2000年2月28日
TNF-α induced p21WAF1 but not bax in colon cancer cells WiDr with mutated p53: Important role of protein stabilization

Nobuyoshi Kobayashi, Yasunari Takada, Misao Hachiya, Koichi Ando, Nobuyuki Nakajima, Makoto Akashi

Cytokine 12(12) 1745-1754 2000年

もっとみる

所属学協会

共同研究・競争的資金等の研究課題

急性放射線障害の発症機序の研究

1991年
Mechanisms for acute injuries caused by radiation

1991年