曽根秀子 (Hideko Sone) - マイポータル

基本情報

所属: 横浜薬科大学薬学部教授

学位: 博士（薬学）(東邦大学薬学部大学院)

研究者番号: 60280715
J-GLOBAL ID: 200901058541288640
researchmap会員ID: 0000040993

外部リンク: http://www.hamayaku.jp/teacher/sone_hideko.html

環境健康科学から未病社会にむけた新たな予防医学的手法の開発を研究の対象にしています。

研究キーワード

研究分野

学歴

受賞

米国毒性学会

曽根秀子

論文

Human-Induced Pluripotent Stem Cell-Derived Neural Organoids as a Novel In Vitro Platform for Developmental Neurotoxicity Assessment

Tsunehiko Hongen, Kenta Sakai, Tomohiro Ito, Xian-Yang Qin, Hideko Sone

International Journal of Molecular Sciences 25(23) 12523-12523 2024年11月21日
Glial differentiation of mouse embryonic-stem-cell-derived neuronal precursors is a sensitive marker for assessing developmental neurotoxicity of insecticides

Tomohiro Ito, Xian-Yang Qin, Yoshika Kurokawa, Yang Zeng, Satoshi Otsuka, Wenlong Wang, Hideko Sone

Fundamental Toxicological Sciences 11(3) 87-98 2024年
Molecular profiling of ginsenoside metabolites to identify estrogen receptor alpha activity

Kikegawa M, Nakajima A, Yu J, Asai M, Uesawa Y, Sone H

Gene 813 146108 2022年3月1日査読有り
Epigenetic effects of insecticides on early differentiation of mouse embryonic stem cells

Wenlong Wang, Tomohiro Ito, Satoshi Otsuka, Hiroko Nansai, Kuniya Abe, Yoichi Nakao, Jun Ohgane, Minoru Yoneda, Hideko Sone

Toxicology in Vitro 75 105174-105174 2021年9月査読有り
Human es and ips cells display less drug resistance than differentiated cells, and naïve-state induction further decreases drug resistance

Yulia Panina, Junko Yamane, Kenta Kobayashi, Hideko Sone, Wataru Fujibuchi

Journal of Toxicological Sciences 46(3) 131-142 2021年
Early Transcriptomic Changes upon Thalidomide Exposure Influence the Later Neuronal Development in Human Embryonic Stem Cell-Derived Spheres.

Mami Kikegawa, Xian-Yang Qin, Tomohiro Ito, Hiromi Nishikawa, Hiroko Nansai, Hideko Sone

International journal of molecular sciences 21(15) 2020年8月3日
Hazard evaluation of air pollution by using the key characteristics approach

Hideko Sone, Tomohiro Ito, Tin-Tin Win-Shwe, Masahiro Miki, Yuji Fujitani, Daisuke Nakajima

IOP Conference Series: Earth and Environmental Science 496 012004-012004 2020年6月18日
Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells.

Junko Yamane, Sachiyo Aburatani, Satoshi Imanishi, Hiromi Akanuma, Reiko Nagano, Tsuyoshi Kato, Hideko Sone, Seiichiroh Ohsako, Wataru Fujibuchi

Nucleic acids research 47(3) 1600-1600 2019年2月20日
Multiparameter Phenotypic Profiling in MCF-7 Cells for Assessing the Toxicity and Estrogenic Activity of Whole Environmental Water

曽根秀子

Environ Sci Technol. 52(16) 9277-9284 2018年7月査読有り
A three-dimensional neurosphere system using human stem cells for nanotoxicology studies

Yang Zeng, Tin-Tin Win-Shwe, Tomohiro Ito, Hideko Sone

Organoids and Mini-Organs 215-226 2018年3月28日
Stem cell-based methods to predict developmental chemical toxicity

Hiroki Takahashi, Xian-Yang Qin, Hideko Sone, Wataru Fujibuchi

Methods in Molecular Biology 1800 475-483 2018年査読有り
[Construction of a High-precision Chemical Prediction System Using Human ESCs].

Yamane J, Aburatani S, Imanishi S, Akanuma H, Nagano R, Kato T, Sone H, Ohsako S, Fujibuchi W

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 138(6) 815-822 2018年査読有り
Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes.

Xian-Yang Qin, Mitsuko Hara, Erik Arner, Yoshikuni Kawaguchi, Ikuyo Inoue, Hideki Tatsukawa, Yutaka Furutani, Keisuke Nagatsuma, Tomokazu Matsuura, Feifei Wei …

EBioMedicine 24 257-266 2017年10月査読有り
Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles.

Kurokawa Y, Sone H, Win-Shwe TT, Zeng Y, Kimura H, Koyama Y, Yagi Y, Matsui Y, Yamazaki M, Hirano S

International journal of nanomedicine 12 3967-3975 2017年査読有り
Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles

Yoshika Kurokawa, Hideko Sone, Tin-Tin Win-Shwe, Yang Zeng, Hiroyuki Kimura, Yosuke Koyama, Yusuke Yagi, Yasuto Matsui, Masashi Yamazaki, Seishiro Hirano

INTERNATIONAL JOURNAL OF NANOMEDICINE 12 3967-3975 2017年査読有り
Effects of Polyamidoamine Dendrimers on a 3-D Neurosphere System Using Human Neural Progenitor Cells

Yang Zeng, Yoshika Kurokawa, Qin Zeng, Tin-Tin Win-Shwe, Hiroko Nansai, Zhenya Zhang, Hideko Sone

TOXICOLOGICAL SCIENCES 152(1) 128-144 2016年7月査読有り
Prediction of developmental chemical toxicity based on gene networks of human embryonic stem cells

Junko Yamane, Sachiyo Aburatani, Satoshi Imanishi, Hiromi Akanuma, Reiko Nagano, Tsuyoshi Kato, Hideko Sone, Seiichiroh Ohsako, Wataru Fujibuchi

NUCLEIC ACIDS RESEARCH 44(12) 5515-5528 2016年7月査読有り
PM2.5 collected in China causes inflammatory and oxidative stress responses in macrophages through the multiple pathways

Kanae Bekki, Tomohiro Ito, Yasuhiro Yoshida, Cuiying He, Keiichi Arashidani, Miao He, Guifan Sun, Yang Zeng, Hideko Sone, Naoki Kunugita …

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 45 362-369 2016年7月査読有り
Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

Yang Zeng, Yoshika Kurokawa, Tin-Tin Win-Shwe, Qin Zeng, Seishiro Hirano, Zhenya Zhang, Hideko Sone

JOURNAL OF TOXICOLOGICAL SCIENCES 41(3) 351-370 2016年6月査読有り
エピジェネティック毒性物質の検出システムの開発

曽根秀子, 阿部訓也, 中尾洋一, 大鐘潤, 桂真理, 藤渕航, 五十嵐勝秀

日本毒性学会学術年会 43 S12-5 2016年