SAKAMOTO Mineshi

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Name
SAKAMOTO Mineshi
Affiliation
National Institute for Minamata Disease
Section
Department of International Affairs and Environmental Sciences
Job title
Director
Degree
Doctor of Medicine
Research funding number
60344420

Research Areas

 
 

Education

 
 
   
 
Kagoshima University
 

Published Papers

 
Maeda E, Murata K, Kumazawa Y, Sato W, Shirasawa H, Iwasawa T, Izumo K, Tatsuta N, Sakamoto M, Terada Y.
Environmental research.   168 357-363   Oct 2018   [Refereed]
Tatsuta N, Nakai K, Sakamoto M, Murata K, Satoh H
Toxics   6(3)    Aug 2018   [Refereed]
Sakamoto M, Tatsuta N, Izumo K, Phan PT, Vu LD, Yamamoto M, Nakamura M, Nakai K, Murata K
Toxics   6(3)    Aug 2018   [Refereed]
Sakamoto M, Tatsuta N, Chan HM, Domingo JL, Murata K, Nakai K
Environmental research   167 15-20   Jul 2018   [Refereed]
Karita K, Iwata T, Maeda E, Sakamoto M, Murata K
Toxics   6(3)    Jul 2018   [Refereed]
Sakamoto M, Chan HM, Domingo JL, Koriyama C, Murata K
Environment international   111 309-315   Feb 2018   [Refereed]
Ser PH, Omi S, Shimizu-Furusawa H, Yasutake A, Sakamoto M, Hachiya N, Konishi S, Nakamura M, Watanabe C
Toxicology letters   267 53-58   Feb 2017   [Refereed]
Ha E, Basu N, Bose-O'Reilly S, Dórea JG, McSorley E, Sakamoto M, Chan HM
Environmental research   152 419-433   Jan 2017   [Refereed]
Sakamoto M, Kakita A, Domingo JL, Yamazaki H, Oliveira RB, Sarrazin SL, Eto K, Murata K
Environmental research   152 446-453   Jan 2017   [Refereed]
Hoang VAT, Sakamoto M, Yamamoto M
The Journal of toxicological sciences   42(4) 509-517   2017   [Refereed]
Hoang VAT, Do HTT, Agusa T, Koriyama C, Akiba S, Ishibashi Y, Sakamoto M, Yamamoto M
The Journal of toxicological sciences   42(5) 651-662   2017   [Refereed]
Sakamoto M, Murata K, Domingo JL, Yamamoto M, Oliveira RB, Kawakami S, Nakamura M
Environmental research   149 287-287   Aug 2016   [Refereed]
Iwata T, Takaoka S, Sakamoto M, Maeda E, Nakamura M, Liu XJ, Murata K
The Journal of toxicological sciences   41(6) 763-763   2016   [Refereed]
Sakamoto M, Itai T, Yasutake A, Iwasaki T, Yasunaga G, Fujise Y, Nakamura M, Murata K, Chan HM, Domingo JL, Marumoto M
Environmental research   143(Pt.A) 55-61   Nov 2015   [Refereed]
Ilmiawati C, Yoshida T, Itoh T, Nakagi Y, Saijo Y, Sugioka Y, Sakamoto M, Ikegami A, Ogawa M, Kayama F
Environmental health and preventive medicine   20(1) 18-27   Jan 2015   [Refereed]
Sakamoto M, Chan HM, Domingo JL, Oliveira RB, Kawakami S, Murata K
Environmental research   136 289-294   Jan 2015   [Refereed]
Yamamoto M, Yanagisawa R, Motomura E, Nakamura M, Sakamoto M, Takeya M, Eto K
Journal of applied toxicology : JAT   34(8) 914-923   Aug 2014   [Refereed]
Nakamura M, Hachiya N, Murata KY, Nakanishi I, Kondo T, Yasutake A, Miyamoto K, Ser PH, Omi S, Furusawa H, Watanabe C, Usuki F, Sakamoto M
Environment international   68 25-32   Jul 2014   [Refereed]
Sakamoto M, Yasutake A, Domingo JL, Chan HM, Kubota M, Murata K
Environment international   60 106-111   Sep 2013   [Refereed]
Horvat M, Sakamoto M, Chan L, Faganeli J
Environmental research   125 1   Aug 2013   [Refereed]
Sakamoto M, Yasutake A, Kakita A, Ryufuku M, Chan HM, Yamamoto M, Oumi S, Kobayashi S, Watanabe C
Environmental science & technology   47(6) 2862-2868   Mar 2013   [Refereed]
Sakamoto M, Chan HM, Domingo JL, Kubota M, Murata K
Ecotoxicology and environmental safety   84 179-184   Oct 2012   [Refereed]
Sakamoto M, Chan HM, Domingo JL, Kawakami S, Murata K
Environment international   44 112-117   Sep 2012   [Refereed]
Mahaffey KR, Sunderland EM, Chan HM, Choi AL, Grandjean P, Mariën K, Oken E, Sakamoto M, Schoeny R, Weihe P, Yan CH, Yasutake A
Nutrition reviews   69(9) 493-508   Sep 2011   [Refereed]
Steckling N, Boese-O'Reilly S, Gradel C, Gutschmidt K, Shinee E, Altangerel E, Badrakh B, Bonduush I, Surenjav U, Ferstl P, Roider G, Sakamoto M, Sepai O, Drasch G, Lettmeier B, Morton J, Jones K, Siebert U, Hornberg C
The Science of the total environment   409(5) 994-1000   Feb 2011   [Refereed]
Sakamoto M, Murata K, Tsuruta K, Miyamoto K, Akagi H
Ecotoxicology and environmental safety   73(6) 1144-1149   Sep 2010   [Refereed]
Sakamoto M, Murata K, Kubota M, Nakai K, Satoh H
Ecotoxicology and environmental safety   73(1) 1-6   Jan 2010   [Refereed]
Cheng J, Yang Y, Ma J, Wang W, Liu X, Sakamoto M, Qu Y, Shi W
Environment international   35(3) 619-625   Apr 2009   [Refereed]
Cheng J, Gao L, Zhao W, Liu X, Sakamoto M, Wang W
The Science of the total environment   407(8) 2625-2630   Apr 2009   [Refereed]
Carratù MR, Coluccia A, Modafferi AM, Borracci P, Scaccianoce S, Sakamoto M, Cuomo V
Bulletin of environmental contamination and toxicology   81(6) 539-542   Dec 2008   [Refereed]
Sakamoto M, Kubota M, Murata K, Nakai K, Sonoda I, Satoh H
Environmental research   106(2) 270-276   Feb 2008   [Refereed]
Liu X, Cheng J, Song Y, Honda S, Wang L, Liu Z, Sakamoto M, Liu Y
Journal of environmental sciences (China)   20(10) 1258-1262   2008   [Refereed]
Liu XJ, Sakamoto M, Kato T, Okamoto M, Arimura K
Nihon eiseigaku zasshi. Japanese journal of hygiene   62(3) 905-910   May 2007   [Refereed]
Iwata T, Sakamoto M, Feng X, Yoshida M, Liu XJ, Dakeishi M, Li P, Qiu G, Jiang H, Nakamura M, Murata K
International archives of occupational and environmental health   80(5) 381-387   Apr 2007   [Refereed]
Coluccia A, Borracci P, Giustino A, Sakamoto M, Carratù MR
Neurotoxicology and teratology   29(2) 282-287   Mar 2007   [Refereed]
Sakamoto M, Feng X, Li P, Qiu G, Jiang H, Yoshida M, Iwaia T, Liu XJ, Murata K
Environmental health and preventive medicine   12(2) 66-70   Mar 2007   [Refereed]
Ohno T, Sakamoto M, Kurosawa T, Dakeishi M, Iwata T, Murata K
Environmental research   103(2) 191-197   Feb 2007   [Refereed]
Mergler D, Anderson HA, Chan LH, Mahaffey KR, Murray M, Sakamoto M, Stern AH, Panel on Health Risks and Toxicological Effects of Methylmercury
Ambio   36(1) 3-11   Feb 2007   [Refereed]
Teraoka H, Kumagai Y, Iwai H, Haraguchi K, Ohba T, Nakai K, Satoh H, Sakamoto M, Momose K, Masatomi H, Hiraga T
Environmental toxicology and chemistry   26(2) 307-312   Feb 2007   [Refereed]
Sakamoto M, Kaneoka T, Murata K, Nakai K, Satoh H, Akagi H
Environmental research   103(1) 106-111   Jan 2007   [Refereed]
Honda S, Hylander L, Sakamoto M
Environmental health and preventive medicine   11(4) 171-176   Jul 2006   [Refereed]
Murata K, Sakamoto M, Nakai K, Dakeishi M, Iwata T, Liu XJ, Satoh H
International archives of occupational and environmental health   79(5) 379-386   May 2006   [Refereed]
Iwata T, Nakai K, Sakamoto M, Dakeishi M, Satoh H, Murata K
Environmental health and preventive medicine   11(1) 17-23   Jan 2006   [Refereed]
Dakeishi M, Nakai K, Sakamoto M, Iwata T, Suzuki K, Liu XJ, Ohno T, Kurosawa T, Satoh H, Murata K
Environmental health and preventive medicine   10(4) 208-212   Jul 2005   [Refereed]
Murata K, Sakamoto M, Nakai K, Weihe P, Dakeishi M, Iwata T, Liu XJ, Ohno T, Kurosawa T, Kamiya K, Satoh H
International archives of occupational and environmental health   77 571-579   Nov 2004   [Refereed]
Sakamoto M, Kakita A, de Oliveira RB, Sheng Pan H, Takahashi H
Brain research. Developmental brain research   152 171-176   Sep 2004   [Refereed]
Sakamoto M, Kubota M, Liu XJ, Murata K, Nakai K, Satoh H
Environmental science & technology   38 3860-3863   Jul 2004   [Refereed]
Sakamoto M, Kubota M
Environmental health and preventive medicine   9(2) 67-69   Mar 2004   [Refereed]
Nakai K, Suzuki K, Oka T, Murata K, Sakamoto M, Okamura K, Hosokawa T, Sakai T, Nakamura T, Saito Y, Kurokawa N, Kameo S, Satoh H
The Tohoku journal of experimental medicine   202 227-237   Mar 2004   [Refereed]
Huan Sheng Pan, Mineshi Sakamoto, Xiao Jie Liu, Makoto Futatsuka
Journal of Health Science   51(1) 41-47   Feb 2005
A cohort study of effects of perinatal exposures to methylmercury and environmentally persistent organic pollutants on neurobehavioral development in Japanese children: Study design and status report.
Satoh H, Nakai K, Suzuki K, Oka T, Murata K, Sakamoto M, Okamura K, Hosokawa T, Sakai T, Nakamura T,Saito Y, Kurokawa N, Kameo S.
RMZ-Materials and Geoenviron   51(1) 512-515   2004
Sakamoto M, Kubota M.
Environmental Health & Preventive Medicine   9(2) 67-69   2004   [Refereed]
Methylmercury exposure in the Tohoku pregnant women.
Nakai K, Murata K, Suzuki K, Oka T, Sakamoto M, Yasutake A, Kameo S, Kurokawa N, Sugawara N, Satoh H.
RMZ-Materials and Geoenvironment   51(1) 485-487   2004
Disruption of postnatal progenitor migration and consequent abnormal pattern of glial distribution in the cerebrum following administration of methylmercury.
Kakita A, Inenaga C, Sakamoto M, Takahashi H
Journal of neuropathology and experimental neurology   62(8) 835-847   Aug 2003   [Refereed]
Iwasaki Y, Sakamoto M, Nakai K, Oka T, Dakeishi M, Iwata T, Satoh H, Murata K
The Tohoku journal of experimental medicine   200(2) 67-73   Jun 2003   [Refereed]
Disruption of postnatal progenitor migration and consequent abnormal pattern of glial distribution in the cerebral cortex following administration of methylmercury.
Journal Neuropathology & Experimental Neurology   62: 835-847    2003
Sakamoto M, Kubota M, Matsumoto S, Nakano A, Akagi H
Environmental research   90(3) 185-189   Nov 2002   [Refereed]
Kakita A, Inenaga C, Sakamoto M, Takahashi H
Acta neuropathologica   104 409-417   Oct 2002   [Refereed]
Sakamoto M, Kakita A, Wakabayashi K, Takahashi H, Nakano A, Akagi H
Brain research   949(1-2) 51-59   Sep 2002   [Refereed]
SAKAMOTO Mineshi
日本衞生學雜誌   54(1)    Apr 1999
Koichi Wakabayashi, Akiyoshi Kakita, Mineshi Sakamoto
Annual report, Brain Research Institute, Niigata University   28    1995
SAKAMOTO Mineshi, NAKANO Atsuhiro, AKAGI Hirokatsu, KITANO Takao, FUTATSUKA Makoto
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   48(5) 911-919   1993
KINJO Yoshihide, HIGASHI Hirofumi, NAKANO Atsuhiro, SAKAMOTO Mineshi, FUTATSUKA Makoto, MAEDA Kazuho
Japanese Journal of Health and Human Ecology   57(4) 142-153   1991
SAKAMOTO Mineshi, NAKANO Atsuhiro, KINJO Yoshihide, HIGASHI Hirofumi, FUTATSUKA Makoto
Japanese Journal of Health and Human Ecology   56(2) 87-96   1990
Ando Tetsuo, Wakisaka Ichiro, Yanagihashi Tsuguo, Sakamoto Mineshi
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   44(3) 733-738   1989
The ability of methylmercury (MMC) to induce lipid peroxidation was tested in rats.<BR>One group of 5 rats (MMC group) took a diet to which 10 ppm of methylmercury was added while another group of 5 rats was fed a diet containing no MMC as a contr...
Ando Tetsuo, Yanagihashi Tsuguo, Wakisaka Ichiro, Sakamoto Mineshi
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   44(5) 993-1001   1989
Four groups of rats, with 5 animals in each, were fed a diet to which 1, 2, 4 or 8ppm of methylmercury (MeHg) were added while another group of 5 rats was fed a diet containing no MeHg as a control. Moreover, each rat was daily supplied the same v...
Ando Tetsuo, Wakisaka Ichiro, Yanagihashi Tsuguo, Sakamoto Mineshi
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   43(3) 717-723   1988
Four groups of male Wistar rats, 4 animals in each, were fed a diet containing 3ppm of methylmercury in addition to ion exchange water containing 0% (control), 1%, 2% and 4% ethanol for drinking during the 40-day experimental period. Samples of ur...
Sakamoto Mineshi, Wakisaka Ichiro, Ando Tetsuo, Yanagihashi Tsuguo
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   43(4) 917-922   1988
Two groups of male Wister rats, 10 animals each, were fed vitamin-E deficient diets containing either of two kinds of lipid, beef tallow containing less amount of polyunsaturated fatty acid or cod-liver oil containing much of one. At the end of 5 ...
Sakamoto Mineshi
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   40(6) 903-909   1986
The effect of dietary lipids on the toxicity of methylmercury (MeHg) was investigated in experimental MeHg poisoning of rats.<br>Three groups of weanling rats, with 8 to 12 animals in each group, were fed on vitamin E-deficient diet containing 10%...
Sakamoto Mineshi
Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene)   40(5) 835-840   1985
The purpose of the present work is to examine the effects of smoking on the amount of ethane expired from the human lungs and on lipid peroxidation in the human body. The amount of ethane in 1000ml of expired air was measured both in smoker...

Misc

 
Sakamoto M, Nakamura M, Murata K.
Nihon Eiseigaku Zasshi.   73(3) 258-264   Sep 2018   [Invited]
Sakamoto M, Itai T, Murata K
Nihon eiseigaku zasshi. Japanese journal of hygiene   72(3) 140-148   2017   [Refereed]
Karita K, Sakamoto M, Yoshida M, Tatsuta N, Nakai K, Iwai-Shimada M, Iwata T, Maeda E, Yaginuma-Sakurai K, Satoh H, Murata K
Nihon eiseigaku zasshi. Japanese journal of hygiene   71(3) 236-251   2016   [Refereed]
坂本 峰至, 村田 勝敬
環境技術   42(10) 584-589   Oct 2013   [Invited]
Sakamoto M, Murata K, Kakita A, Sasaki M.
Environmental chemistry and toxicology of mercury   15 501-516   2012   [Invited]
Murata K, Yoshida M, Sakamoto M, Iwai-Shimada M, Yaginuma-Sakurai K, Tatsuta N, Iwata T, Karita K, Nakai K
Nihon eiseigaku zasshi. Japanese journal of hygiene   66(4) 682-695   Sep 2011   [Refereed]
Minamata disease
Murata K, Sakamoto M.
encyclopedia of environmental health   3 774-780   2011   [Invited]
坂本 峰至, 山元 恵
Food sanitation research   60(12) 35-41   Dec 2010   [Invited]
坂本 峰至, 佐々木 眞敬
Japanese journal of clinical medicine   68(0) 576-580   Jan 2010   [Invited]
SAKAMOTO Mineshi, AKAGI Hirokatsu
Waste Management Research   16(4) 185-190   Jul 2005
Sakamoto M, Yasutake A, Satoh H.
Dynamics of mercury pollution on regional and global scales: atmospheric processes and human exposures around the world.   125-146   2005

Conference Activities & Talks

 
Relative uptake of methylmercury was higher in the brain of fetal and neonate than weanling and adult rats.
SAKAMOTO MineshiMineshi Sakamoto, Nozomi Tatsuta, Laurie Chan, José Domingo, Katsuyuki Murata, Kunihiko Nakai.
The ISES-ISEE 2018 Joint Annual Meeting   Aug 2018   
Mercury speciation in preserved sludge which is estimated to be remaining under the reclaimed land area of Minamata Bay, Japan.
M Sakamoto, T Itai, K Marumoto, K Mori, M Horvat, A Poulain, H Kodamatani, T Tomiyasu.
4th International Conference on Environmental and Economic Impact on Sustainable Development   Jun 2018   
Mercury speciation in preserved sludge which is estimated to be remaining under the reclaimed land area of Minamata Bay Japan.
Sakamoto M, Itai T, Marumoto K, Mori K, Horvat M, Poulain A, Kodamatani H, Tomiyasu.
53rd Congress of the Euro Societies of Toxicology   Sep 2017   
Health impact and HBM in populations exposed to elemental mercury vapor and methylmercury. [Invited]
SAKAMOTO Mineshi
WHO Workshop at ICMGP-2017   Jul 2017   
Methylmercury versus selenium, vitamin E, and docosahexaenoic acid in fetal circulation: comparison with maternal status.
Sakamoto M, Chan HM, Domingo JL, Yamamoto M, Murata K.
13th International Conference on Mercury as a Global Pollutant   Jul 2017   
Mercury, selenium, DHA, and vitamin E profiles in maternal and cord blood.
Sakamoto M, Yamamoto M, Chan HM, Tatsuta N, Nakai K, Murata K:
5th Conference on Prenatal Programming and Toxicity   Nov 2016   
Relationship between concentrations of DHA, selenium and mercury in maternal and cord blood.
Sakamoto M, HM Chan, Nakamura M, Tatsuta N.
15th World Congress of the International Association for the Scientific Study of Intellectual and Developmental Disabilities Congress   Aug 2016   
SAKAMOTO Mineshi
Annual Meeting of the Japanese Society of Toxicology   Jun 2016   
Implications of mercury concentrations in umbilical cord tissue in relation to maternal hair segments as biomarkers for prenatal exposure to methylmercury.
Sakamoto M, Murata K, Domingo JL, Yamamoto M, Oliveira RB, Kawakami S, Nakamura M
6th Federation of European Societies on Trace Elements and Minerals   May 2016   
Fetuses as a high-risk group to methylmercury exposure. [Invited]
SAKAMOTO Mineshi
9th Congress of Toxicology in Developing Countries   Nov 2015   
Detoxification of methylmercury by formation of mercury selenide in muscle of toothed-whale.
Sakamoto M, Itai T, Nakamura N, Sawada M, Domingo JL.
The 51st Congress of the European Societies of Toxicology   Sep 2015   
Significance of fingernail and toenail mercury concentrations as biomarkers for prenatal methylmercury exposure.
Sakamoto M, Murata K, Chan HM, Oliveila R, Domingo JL.
The 12th International Conference on Mercury as a Global Pollutant   Jun 2015   
Global mercury pollution and fetuses as a high-risk group to methylmercury exposure. [Invited]
SAKAMOTO Mineshi
Jun 2015   
Significance of nail mercury concentrations as a biomarker of prenatal methylmercury exposure in relation to segmental hair mercury concentrations at parturition.
Sakamoto M, Murata K, Chan HM, Oliveila R, Doming J.
The 50th Congress of the European Societies of Toxicology   Sep 2014   
Mercury and selenium concentrations in tooth-whale meats and their element profile in blood of the inhabitants in a whaling town, Japan.
Sakamoto M, Marumoto M, Yasutake A, Iwasaki T, Yasunaga G, Fujise M, Nakamura M, Murata K, Chan HM
The EcoHealth 2014 conference   Aug 2014   
Methylmercury and fatty acids in exposed populations by eating fish.
SAKAMOTO Mineshi
2nd International Symposium of Mercury Impacts on the Environment and Human Health   Mar 2014   
Hg speciation and Se concentrations in tooth-whale meats consumed in Taiji Town, Japan.
SAKAMOTO Mineshi
The 11th International Conference on Mercury as a Global Pollutant   Aug 2013   
Mercury as a global pollutant and health effects of methylmercury. [Invited]
SAKAMOTO Mineshi
Seminar at National Institute of Environmental Research   Jun 2013   
Relationship between trace element concentrations in chorionic tissue of placenta and umbilical cord: Specificity of placental transfer of methylmercury. [Invited]
SAKAMOTO Mineshi
Mini-Symposium "Academic Conference on Heavy Metal Exposure durning Human Life", Heavy Metal Exposure Environmental Health Cente (Dong A University)   Jun 2013   
Element profiles of cord tissue and placenta and their usefulness as predictors of prenatal exposure to elements in ordinary Japanese population.
Sakamoto M, Chan HM, Domingo JL, Murata K.
The 5th International FESTEM Symposium on Trace Elements and Minerals   May 2013   
Selenomethionine protects against neuronal degeneration by methylmercury in the developing rat brain.
Sakamoto M, Yasutake A, Kakita M, et al.
Environmental Health 2013   Mar 2013   
Significances of cord tissue and placenta to predict the metal exposure to fetuses.
Sakamoto M, Murata M, Domingo JL, Kubota M, Chan HM.
The 48th Congress of the European Societies of Toxicology   Jun 2012   
Placental transfer of heavy metals and the changes in their body burden in infants during early-breastfeeding period. [Invited]
SAKAMOTO Mineshi
NIMD FORUM 2012   Feb 2012   
Protective effecta of selenomethionine against methylmercury-induced neuronal degeneration in developing rat brain.
Sakamoto M, Yasutake A, Yamamoto M, Chan HM, Kakita A, Oumi A, Watanabe C.
Neurotoxicology Conference   Nov 2011   
Differences in heavy metal transfer from mother to child during gestation and lactation.
Sakamoto M, Murata K, Kubota M, Nakai K, Satoh H.
The 47th Congress of the European Societies of Toxicology   Aug 2011   
Retrospective study on temporal and regional variations of methylmercury concentrations in preserved umbilical cords collected from inhabitants of the Minamata area, Japan.
Sakamoto M, Murata K, Tsuruta K, Miyamoto K, Akagi H.
The 10th International Conference on Mercury as a Global Pollutant   Jul 2011   
Protective effects of selenomethionine against methylmercury-induced neuronal degeneration in developing rat brain. [Invited]
SAKAMOTO Mineshi
NIMD FORUM 2011   Jan 2011   
Relationship between methylmercury and DHA in Pregnant Women and fetuses: The risks and benefits of fish consumption.
SAKAMOTO Mineshi
International Union of Toxicology (IUTOX), the XII International Congress of Toxicology   Jul 2010   
Temporal and regional variations of methylmercury concentrations in preserved umbilical cords collected from inhabitants of Minamata area, Japan.
SAKAMOTO Mineshi
SETAC Asia-Pacific 2010 Conference   Jul 2010   
Health Risks of Methylmercury with Special Reference to Fetus.
SAKAMOTO Mineshi
GOLDSCHMID 2010   Jun 2010   
NAKANO Atsuhiro
日本衞生學雜誌   15 Apr 1999   

Research Grants & Projects

 
1.Behavioral and neurochemical studies on the effects of methylmercury on the developing central nervous system 2.Studies on the effects of methylmercury pollution on human health