HIROSE Akihiko

J-GLOBAL         Last updated: Dec 12, 2018 at 14:07
HIROSE Akihiko
National Institute of Health Sciences
Division of Risk Assessment
Job title
Doctor of Philosophy(Tohoku University)

Research Areas


Academic & Professional Experience

: Researcher, Division of Toxicology, NIHS
: Senior Researcher, Division of Risk Assessment,


Graduate School, Division of Medicine, Tohoku University
Faculty of Pharmaceutical Science, Toyama Medical and Pharmaceutical University

Committee Memberships

The Japanese Society of Toxicological Sciences  Councilor
Society of Toxicology  

Published Papers

Tanabe S, Kobayashi K, Matsumoto M, Serizawa H, Igarashi T, Yamada T, Hirose A.,
Fundamental Toxicological Sciences   4(6) 247-259   2017   [Refereed]
Tanabe S, Ohara M, Ito M, Noda A, Kobayashi K, Matsumoto M, Hirose A.,
Fundamental Toxicological Sciences   4(5) 207-218   2017   [Refereed]
Watanabe W, Hirose A, Takeshita T, Hashiguchi S, Sakata K, Konno K, Miyauchi A, Akashi T, Yoshida H, Sugita C, Kurokawa M.,
J Toxicol Sci   42 789-795   2017   [Refereed]
Shigemoto-Mogami Y, Hoshikawa K, Hirose A, Sato K.,
J Toxicol Sci   41 501-509   2016   [Refereed]
Using in vitro structural alerts for chromosome damage to predict in vivo activity and direct future testing
Canipa S, Cayley A, Drewe WC, Williams RV, Hamada S, Hirose A, Honma M, Morita T.,
Mutagenesis   31 17-25   2016   [Refereed]
Risk assessment of skin lightening cosmetics containing hydroquinone
Matsumoto M., Todo H., Akiyama T., Hirata-Koizumi M., Sugibayashi K., Ikarashi Y., Ono A., Hirose A. and Yokoyama K.,
Regul Toxicol Pharmacol   81 128-135   2016   [Refereed]
Chronic toxicity of an environmentally relevant mixture of pharmaceuticals to three aquatic organisms (algadaphnid and fish)
Watanabe H, Tamura I, Abe R, Takanobu H, Nakamura A, Suzuki T, Hirose A, Nishimura T, Tatarazako N.,
Environ Toxicol Chem   35 996-1006   2016   [Refereed]
Multiwalled carbon nanotubes intratracheally instilled into the rat lung induce development of pleural malignant mesothelioma and lung tumors
Suzui M, Futakuchi M, Fukamachi K, Numano T, Abdelgied M, Takahashi S, Ohnishi M, Omori T, Tsuruoka S, Hirose A., Kanno J, Sakamoto Y, Alexander DB, Alexander WT, Jiegou X, Tsuda H.,
Cancer Sci   107 924-935   2016   [Refereed]
Repeated dose and reproductive/developmental toxicity of perfluorododecanoic acid in rats
Kato H, Fujii S, Takahashi M, Matsumoto M, Hirata-Koizumi M, Ono A, Hirose, A.,
Environ Toxicol   30 1244-1263   2015   [Refereed]

Research Grants & Projects

Integrated research on water quality risk management of the drinking water
Health and Labour Sciences Research Grants
Project Year: 2007 - 2009
Study on uncertainty of toxicity data and the extrapolation to humans
The Other Research Programs
Project Year: 2007 - 2009
Research on hazard characterization and toxico-kinetic analysis of the manufactured nanomaterials for the establishment of health risk assessment methodology
Health and Labour Sciences Research Grants
Project Year: 2006 - 2007
Studies on the risk assessment of synthetic resin used for food contact utensils and packages
The Other Research Programs
Project Year: 2005 - 2007