MISC

1989年

Determination of selenium in drugs by oxygen flask combustion and ion chromatography

Journal of Chromatography A
  • Mitsunori Murayama
  • ,
  • Masao Suzuki
  • ,
  • Shoji Takitani

463
C
開始ページ
147
終了ページ
152
記述言語
英語
掲載種別
DOI
10.1016/S0021-9673(01)84462-9

A method is described for the determination of trace selenium (impurities in medicinal organic compounds) by ion chromatography (IC) after oxygen flask combustion. All selenium compounds formed by oxygen flask combustion are converted to selenate ion by heating with nitric acid and potassium permanganate. The selenate ion is then determined by IC, using a simple recycle system to eliminate interfering ions. the detection limit of selenium is 0.4 nmol in 50 mg of-sample. The recoveries of selenium added to seven drugs are ca. 95-103% with relative standard derivations of 1-6%. © 1989.

リンク情報
DOI
https://doi.org/10.1016/S0021-9673(01)84462-9
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/2715233
ID情報
  • DOI : 10.1016/S0021-9673(01)84462-9
  • ISSN : 0021-9673
  • PubMed ID : 2715233
  • SCOPUS ID : 0024595676

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