山崎聖美 (Tomomi Yamazaki) - マイポータル

基本情報

所属: 国立研究開発法人医薬基盤・健康・栄養研究所国立健康・栄養研究所臨床栄養研究部室長

学位: 理学博士(東京大学)

J-GLOBAL ID: 200901055825140287
researchmap会員ID: 0000041458

研究キーワード

研究分野

ライフサイエンス / 分子生物学 /

論文

Effective Food Ingredients for Fatty Liver: Soy Protein β-Conglycinin and Fish Oil.

Yamazaki T, Li D, Ikaga R

International journal of molecular sciences 19(12) 2018年12月査読有り
Soya protein β-conglycinin ameliorates fatty liver and obesity in diet-induced obese mice through the down-regulation of PPARγ.

Li D, Ikaga R, Yamazaki T

Br J Nutr 119(11) 1220-1232 2018年6月査読有り
Dietary β-conglycinin prevents acute ethanol-induced fatty liver in mice

Ikaga R, Li D, Yamazaki T

Biochem Biophys Res Commun 493(1) 542-547 2017年11月査読有り
PTPRJ inhibits leptin signaling, and induction of PTPRJ in the hypothalamus is a cause of the development of leptin resistance.

Shintani T, Higashi S, Suzuki R, Takeuchi Y, Ikaga R, Yamazaki T, Kobayashi K, Noda M

Sci Rep 7(1) 11627 2017年9月査読有り
The effects on weight loss and gene expression in adipose and hepatic tissues of very-low carbohydrate and low-fat isoenergetic diets in diet-induced obese mice

Tomomi Yamazaki, Sumire Okawa, Mayumi Takahashi

NUTRITION & METABOLISM 13 78 2016年11月査読有り
Producing PPARgamma2 knockdown in mouse liver

Tomomi Yamazaki, Osamu Ezaki

Methods in Molecular Biology 952 99-116 2013年査読有り
Role of DNA Methylation in the Regulation of Lipogenic Glycerol-3-Phosphate Acyltransferase 1 Gene Expression in the Mouse Neonatal Liver

Tatsuya Ehara, Yasutomi Kamei, Mayumi Takahashi, Xunmei Yuan, Sayaka Kanai, Erina Tamura, Miyako Tanaka, Tomomi Yamazaki, Shinji Miura, Osamu Ezaki, Takayoshi Suganami, Masaki Okano, Yoshihiro Ogawa

DIABETES 61(10) 2442-2450 2012年10月査読有り
The ddY mouse: a model of postprandial hypertriglyceridemia in response to dietary fat

Tomomi Yamazaki, Kyoko Kishimoto, Osamu Ezaki

JOURNAL OF LIPID RESEARCH 53(10) 2024-2037 2012年10月査読有り
Hepatic peroxisome proliferator-activated receptor-γ-fat-specific protein 27 pathway contributes to obesity-related hypertension via afferent vagal signals.

Uno K, Yamada T, Ishigaki Y, Imai J, Hasegawa Y, Gao J, Kaneko K, Matsusue K, Yamazaki T, Oka Y, Katagiri H

Eur Heart J 33(10) 1279-1289 2012年5月査読有り
Dietary β-conglycinin prevents fatty liver induced by a high-fat diet by a decrease in peroxisome proliferator-activated receptor γ2 protein.

Yamazaki T, Kishimoto K, Miura S, Ezaki O

The Journal of nutritional biochemistry 23(2) 123-132 2012年2月査読有り
An increase in liver PPARγ2 is an initial event to induce fatty liver in response to a diet high in butter: PPARγ2 knockdown improves fatty liver induced by high-saturated fat.

Yamazaki T, Shiraishi S, Kishimoto K, Miura S, Ezaki O

The Journal of nutritional biochemistry 22(6) 543-553 2011年6月査読有り
Impaired Insulin Signaling in Endothelial Cells Reduces Insulin-Induced Glucose Uptake by Skeletal Muscle

Tetsuya Kubota, Naoto Kubota, Hiroki Kumagai, Shinichi Yamaguchi, Hideki Kozono, Takehiro Takahashi, Mariko Inoue, Shinsuke Itoh, Iseki Takamoto, Takayoshi Sasako, Katsuyoshi Kumagai, Tomoko Kawai, Shinji Hashimoto, Tsuneo Kobayashi, Maki Sato, Kumpei Tokuyama, Satoshi Nishimura, Masaki Tsunoda, Tomohiro Ide, Koji Murakami, Tomomi Yamazaki, Osamu Ezaki, Koichi Kawamura, Hirotake Masuda, Masao Moroi, Kaoru Sugi, Yuichi Oike, Hiroaki Shimokawa, Nobuyuki Yanagihara, Masato Tsutsui, Yasuo Terauchi, Kazuyuki Tobe, Ryozo Nagai, Katsuo Kamata, Kenji Inoue, Tatsuhiko Kodama, Kohjiro Ueki, Takashi Kadowaki

CELL METABOLISM 13(3) 294-307 2011年3月査読有り
Fish oil fed prior to ethanol administration prevents acute ethanol-induced fatty liver in mice

Satoshi Wada, Tomomi Yamazaki, Yukari Kawano, Shinji Miura, Osamu Ezaki

JOURNAL OF HEPATOLOGY 49(3) 441-450 2008年9月査読有り
Fish oil prevents sucrose-induced fatty liver but exacerbates high-safflower oil-induced fatty liver in ddY mice

Tomomi Yamazaki, Akiko Nakamori, Eriko Sasaki, Satoshi Wada, Osamu Ezaki

HEPATOLOGY 46(6) 1779-1790 2007年12月
Overexpression of peroxisome proliferators-activated receptor γ co-activator-1 α leads to muscle atrophy with depletion of ATP

Miura S, Tomitsuka E, Kamei Y, Yamazaki T, Kai Y, Tamura M, Kita K, Nishino I, Ezaki O

Am J Pathol 169(4) 1129-1139 2006年10月
Increased VLDL secretion and gonadal fat mass in mice over-expressing liver acyl CoA: Diacylglycerol acyltransferase 1

Yamazaki T, Sasaki E, Kakinuma C, Yano T, Miura S, Ezaki O

J Biol Chem 280(22) 21506-24514 2005年
Possible enhancing effects of atrazine and nonylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats

K Fukamachi, BS Han, CK Kim, N Takasuka, Y Matsuoka, E Matsuda, T Yamasaki, H Tsuda

CANCER SCIENCE 95(5) 404-410 2004年5月
Inhibitory effects of 17β-estradiol and 4-n-octylphenol on 7, 12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats

Han BJ, Fukamachi K, Takasuka N, Ohnishi T, Maeda M, Yamazaki T, Tsuda H

Carcinogenesis 23(7) 1209-1215 2002年7月
Cathepsin G enhances human natural killer cytotoxicity

T Yamazaki, Y Aoki

IMMUNOLOGY 93(1) 115-121 1998年1月
Cathepsin G binds to human lymphocytes

T Yamazaki, Y Aoki

JOURNAL OF LEUKOCYTE BIOLOGY 61(1) 73-79 1997年1月

もっとみる

MISC

Inhibitory effects of 17β-estradiol and 4-n-octylphenol on 7, 12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats

Carcinogenesis 23(7) : 1209-1215 2002年
Cathepsin G enhances human natural killer cytotoxicity

Immunology 93:115-121 1998年
Cathepsin G binds to human lymphocytes

Journal of Leukocyte Biology 61(1)73-79 1997年
Stimulation of Human Lymphocytes by Cathepsin G

Cellular Immunology 160(1)24-32 1995年
Induction of Activated Killer Cells From Human Lymphocytes by Medullasin (A Serine Protease in Bone Marrow Cells)

Immunology 75:481-487 1992年
Isolation and Partial Characterization of Human and Porcine Gastric Mucins

Biomedical Research 13(2):149-154 1992年

所属学協会

共同研究・競争的資金等の研究課題

生活習慣病に関する研究

2002年 - 2025年
・・・

2002年 - 2025年
Metabolic syndrome