1999年5月24日
Inhibitory effect of Epstein-Barr virus activation by Citrus fruits, a cancer chemopreventor
Cancer Letters
- 巻
- 139
- 号
- 2
- 開始ページ
- 227
- 終了ページ
- 236
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1016/S0304-3835(99)00041-5
To search useful compounds in Citrus fruit for cancer chemoprevention, we carried out a primary screening of extracts of fruit peels and seeds from 78 species of the genus Citrus and those from two Fortunella and one Poncirus species, which were closely related to the genus Citrus. These Citrus extracts inhibited the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) as a useful screening method for anti-tumor promoters. Our results indicated that Citrus containing substances may be inhibit susceptibility factors involved in the events leading to the development of cancer. Copyright (C) 1999 Elsevier Science Ireland Ltd.
- リンク情報
- ID情報
-
- DOI : 10.1016/S0304-3835(99)00041-5
- ISSN : 0304-3835
- identifiers.cinii_nr_id : 9000239248799
- PubMed ID : 10395183
- SCOPUS ID : 0032959721