論文

査読有り
2021年6月

Improvement of hemolysis performance in a hydrodynamically levitated centrifugal blood pump by optimizing a shroud size

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
  • Ryo Kosaka
  • ,
  • Daisuke Sakota
  • ,
  • Masahiro Nishida
  • ,
  • Osamu Maruyama
  • ,
  • Takashi Yamane

24
2
開始ページ
157
終了ページ
163
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10047-020-01240-6

We have developed a hydrodynamically levitated centrifugal blood pump. In the blood pump having hydrodynamic bearings, the narrow bearing gap has a potential for high hemolysis. The purpose of the this study is to improve hemolysis performance in a hydrodynamically levitated centrifugal blood pump by optimizing a shroud size. The impeller was levitated passively at the position where the thrust forces acting on the impeller were balanced. We focused on a size of a bottom shroud with a hydrodynamic bearing that could change the bottom hydrodynamic force to balance the thrust force at the wide bearing gap for reducing hemolysis. Five test models with various shroud size were compared: 989 mm2 (HH-10.5), 962 mm2 (HH-12), 932 mm2 (HH-13.5), 874 mm2 (HH-16), and 821 mm2 (HH-18). A numerical analysis was first performed to estimate the bearing gaps in the test model. The bearing gaps were then measured to validate the numerical analysis. Finally, an in vitro hemolysis test was performed. The numerical analysis revealed that the HH-13.5 model had the widest bearing gap of 129 µm. In the measurement test, the estimation error for the bearing gap was less than 10%. In the hemolysis test, the HH-13.5 model achieved the lowest hemolysis level among the five models. The present study demonstrated that the numerical analysis was found to be effective for determining the optimal should size, and the HH-13.5 model had the optimal shroud size in the developed hydrodynamically levitated centrifugal blood pump to reduce hemolysis.

リンク情報
DOI
https://doi.org/10.1007/s10047-020-01240-6
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33428006
ID情報
  • DOI : 10.1007/s10047-020-01240-6
  • PubMed ID : 33428006

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