論文

査読有り
2021年6月

Plasma skimming efficiency of human blood in the spiral groove bearing of a centrifugal blood pump

Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs
  • Daisuke Sakota
  • ,
  • Kazuki Kondo
  • ,
  • Ryo Kosaka
  • ,
  • Masahiro Nishida
  • ,
  • Osamu Maruyama

24
2
開始ページ
126
終了ページ
134
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10047-020-01221-9
出版者・発行元
SPRINGER JAPAN KK

This work investigates the plasma skimming effect in a spiral groove bearing within a hydrodynamically levitated centrifugal blood pump when working with human blood having a hematocrit value from 0 to 40%. The present study assessed the evaluation based on a method that clarified the limitations associated with such assessments. Human blood was circulated in a closed-loop circuit via a pump operating at 4000 rpm at a flow rate of 5 L/min. Red blood cells flowing through a ridge area of the bearing were directly observed using a high-speed microscope. The hematocrit value in the ridge area was calculated using the mean corpuscular volume, the bearing gap, the cross-sectional area of a red blood cell, and the occupancy of red blood cells. The latter value was obtained from photographic images by dividing the number of pixels showing red blood cells in the evaluation area by the total number of pixels in this area. The plasma skimming efficiency was calculated as the extent to which the hematocrit of the working blood was reduced in the ridge area. For the hematocrit in the circuit from 0 to 40%, the plasma skimming efficiency was approximately 90%, meaning that the hematocrit in the ridge area became 10% as compared to that in the circuit. For a hematocrit of 20% and over, red blood cells almost completely occupied the ridge. Thus, a valid assessment of plasma skimming was only possible when the hematocrit was less than 20%.


リンク情報
DOI
https://doi.org/10.1007/s10047-020-01221-9
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33113050
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000584895600001&DestApp=WOS_CPL
ID情報
  • DOI : 10.1007/s10047-020-01221-9
  • ISSN : 1434-7229
  • eISSN : 1619-0904
  • PubMed ID : 33113050
  • Web of Science ID : WOS:000584895600001

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