論文

査読有り 筆頭著者
2017年3月

Long-term durability test of axial-flow ventricular assist device under pulsatile flow

JOURNAL OF ARTIFICIAL ORGANS
  • Masahiro Nishida
  • ,
  • Ryo Kosaka
  • ,
  • Osamu Maruyama
  • ,
  • Takashi Yamane
  • ,
  • Akio Shirasu
  • ,
  • Eisuke Tatsumi
  • ,
  • Yoshiyuki Taenaka

20
1
開始ページ
26
終了ページ
33
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10047-016-0933-6
出版者・発行元
SPRINGER JAPAN KK

A long-term durability test was conducted on a newly developed axial-flow ventricular assist device (VAD) with hydrodynamic bearings. The mock circulatory loop consisted of a diaphragm pump with a mechanical heart valve, a reservoir, a compliance tank, a resistance valve, and flow paths made of polymer or titanium. The VAD was installed behind the diaphragm pump. The blood analog fluid was a saline solution with added glycerin at a temperature of 37 A degrees C. A pulsatile flow was introduced into the VAD over a range of flow rates to realize a positive flow rate and a positive pressure head at a given impeller rotational speed, yielding a flow rate of 5 L/min and a pressure of 100 mmHg. Pulsatile flow conditions were achieved with the diastolic and systolic flow rates of similar to 0 and 9.5 L/min, respectively, and an average flow rate of similar to 5 L/min at a pulse rate of 72 bpm. The VAD operation was judged by not only the rotational speed of the impeller, but also the diastolic, systolic, and average flow rates and the average pressure head of the VAD. The conditions of the mock circulatory loop, including the pulse rate of the diaphragm pump, the fluid temperature, and the fluid viscosity were maintained. Eight VADs were tested with testing periods of 2 years, during which they were continuously in operation. The VAD performance factors, including the power consumption and the vibration characteristics, were kept almost constant. The long-term durability of the developed VAD was successfully demonstrated.


リンク情報
DOI
https://doi.org/10.1007/s10047-016-0933-6
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000395871500004&DestApp=WOS_CPL
URL
http://orcid.org/0000-0001-8075-2269
ID情報
  • DOI : 10.1007/s10047-016-0933-6
  • ISSN : 1434-7229
  • eISSN : 1619-0904
  • ORCIDのPut Code : 46043612
  • Web of Science ID : WOS:000395871500004

エクスポート
BibTeX RIS