2003年10月
Optical resolution of racemic 2-hydroxy octanoic acid by lipase-catalyzed hydrolysis in a biphasic membrane reactor
BIOTECHNOLOGY LETTERS
- ,
- 巻
- 25
- 号
- 19
- 開始ページ
- 1591
- 終了ページ
- 1595
- 記述言語
- 英語
- 掲載種別
- DOI
- 10.1023/A:1025620103297
- 出版者・発行元
- KLUWER ACADEMIC PUBL
Racemic 2-hydroxy octanoic acid methyl ester was optically resolved by lipase-catalyzed hydrolysis in a biphasic membrane reactor using hydrophilic/hydrophobic capillary membranes. In a buffer/hexane biphasic membrane reactor using hydrophilic ultrafiltration membranes, (S)-2-hydroxy octanoic acid was recovered from the aqueous phase at 59-67% yield and 0.9-0.92 enantiomeric excess (ee), and the ester of (R)-isomer was recovered from the organic phase at 73-75% yield and 0.92-0.99 ee.
- リンク情報
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- DOI
- https://doi.org/10.1023/A:1025620103297
- CiNii Articles
- http://ci.nii.ac.jp/naid/80016164754
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/14584912
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000185207600002&DestApp=WOS_CPL
- ID情報
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- DOI : 10.1023/A:1025620103297
- ISSN : 0141-5492
- CiNii Articles ID : 80016164754
- PubMed ID : 14584912
- Web of Science ID : WOS:000185207600002