2003年6月
Adsorptive stripping voltammetric measurement of acetylcholinesterase activity: Application to monitoring organophosphorus pesticides
ELECTROCHEMISTRY
- ,
- ,
- ,
- 巻
- 71
- 号
- 6
- 開始ページ
- 411
- 終了ページ
- 413
- 記述言語
- 英語
- 掲載種別
- 出版者・発行元
- ELECTROCHEMICAL SOC JAPAN
Organophosphorus pesticides (OPPs), diazinon (0.01-0.05 ppm) and ethylthiometon (0.01-0.2 ppm), were determined by monitoring the activity change of acetylcholinesterase (AChE), based on the chemisorption/desorption-process of thiocholine on a silver electrode as follows. Thiocholine, which was produced through the AChE-catalyzed reaction, was chemisorbed on the silver electrode surface, and then was cathodically desorbed. The electrical charge passed through the desorption process was proportional to the number of adsorbed thiocholine molecules, hence to the AChE activity. Thus the inhibition of the AChE activity by OPPs could be monitored from the decrease in the electrical charge for the desorption process.
- リンク情報
- ID情報
-
- ISSN : 1344-3542
- Web of Science ID : WOS:000183761100009