髙桑弘樹 (HIROKI TAKAKUWA) - マイポータル

基本情報

所属: 京都産業大学生命科学部先端生命科学科教授

学位: Veterinary Medical Sciences(不明)
博士（獣医学）(北海道大学)

J-GLOBAL ID: 200901013351644349
researchmap会員ID: 0000109026

研究キーワード

インフルエンザウイルス

研究分野

経歴

2014年 - 現在

:京都産業大学総合生命学部動物生命医科学科教授
2010年 - 2014年

:京都産業大学総合生命学部動物生命医科学科准教授
2009年 - 2010年

:京都産業大学工学部生物工学科准教授
2007年 - 2009年

:京都産業大学鳥インフルエンザ研究センター主任研究員
2006年 - 2007年

:京都産業大学鳥インフルエンザ研究センター研究員
2005年 - 2006年

:北海道大学大学院獣医学研究科客員研究員
2002年 - 2005年

:アメリカ食品安全局生物学的製剤評価研究センター研究員
1998年 - 2002年

:名古屋大学大学院医学研究科附属病態制御研究施設日本学術振興会未来開拓研究推進事業リサーチアソシエイト

学歴

論文

Accumulation of a soluble form of human nectin-2 is required for exerting the resistance against herpes simplex virus type 2 infection in transfected cells

Y. FUJIMOTO, K. OZAKI, N. IWAMORI, H. TAKAKUWA, E. ONO

Acta Virologica 60(1) 41-48-8 2016年
Cross-protective potential of anti-nucleoprotein human monoclonal antibodies against lethal influenza A virus infection

Fujimoto Y, Tomioka Y, Takakuwa H, Uechi GI, Yabuta T, Ozaki K, Suyama H, Yamamoto S, Morimatsu M, Mai LQ …

Journal of General Virology 97(9) 2104-2116 2016年
Systemic L-Kynurenine sulfate administration disrupts object recognition memory, alters open field behavior and decreases c-Fos immunopositivity in C57BI/6 mice

Varga D, Herédi J, Kánvási Z, Ruszka M, Kis Z, Ono E, Iwamori N, Iwamori T, Takakuwa H, Vécsei L …

Frontiers in Behavioral Neuroscience 9(157) 2015年
Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Masami Morimatsu, Yukiko Tomioka …

PREVENTIVE VETERINARY MEDICINE 103(2-3) 192-200 2012年2月査読有り
Isolation and characterization of H6N1 and H9N2 avian influenza viruses from Ducks in Hanoi, Vietnam

Kozue Hotta, Hiroki Takakuwa, Quynh Mai Thi Le, Song Lien Phuong, Toshiyuki Murase, Etsuro Ono, Toshihiro Ito, Koichi Otsuki, Tetsu Yamashiro

VIRUS RESEARCH 163(2) 448-453 2012年2月査読有り
Characterization of H5N1 highly pathogenic avian influenza virus strains isolated from migratory waterfowl in Mongolia on the way back from the southern Asia to their northern territory

Yoshihiro Sakoda, Sengee Sugar, Damdinjav Batchluun, Tseren-Ochir Erdene-Ochir, Masatoshi Okamatsu, Norikazu Isoda, Kosuke Soda, Hiroki Takakuwa, Yoshimi Tsuda, Naoki Yamamoto …

VIROLOGY 406(1) 88-94 2010年10月査読有り
Development of a new disinfectant with very strong anti-influenza viral activity: A preliminary report

Hiroki Takakuwa, Toshiyuki Maruoka, Tadayo Hata, Masaaki Miyazawa, Tomoyo Hata, Hitoshi Toshimori, Koichi Otsuki

Environmental Health and Preventive Medicine 15(2) 121-123 2010年3月査読有り
Development of reverse transcription-loop-mediated isothermal amplification (RT-LAMP) assay for detection of avian influenza viruses in field specimens

Shivakoti S, Ito H, Murase T, Ono E, Takakuwa H, Yamashiro T, Otsuki K, Ito T.

Journal of Veterinary Medical Science 72(4) 519-523-523 2010年
Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Tsuyoshi Yamaguchi, Toshihiro Ito …

MICROBIOLOGY AND IMMUNOLOGY 54(1) 58-62 2010年1月査読有り
Susceptibility of two species of wild terrestrial birds to infection with a highly pathogenic avian influenza virus of H5N1 subtype

Yoshikazu Fujimoto, Hiroshi Ito, Kyoko Shinya, Tsuyoshi Yamaguchi, Tatsufumi Usui, Toshiyuki Murase, Hiroichi Ozaki, Etsuro Ono, Hiroki Takakuwa, Koichi Otsuki …

AVIAN PATHOLOGY 39(2) 95-98 2010年査読有り
A vaccine prepared from a non-pathogenic H7N7 virus isolated from natural reservoir conferred protective immunity against the challenge with lethal dose of highly pathogenic avian influenza virus in chickens

Saori Sakabe, Yoshihiro Sakoda, Yoshinari Haraguchi, Norikazu Isoda, Kosuke Soda, Hiroki Takakuwa, Kazue Saijo, Akira Sawata, Katsumi Kume, Junko Hagiwara …

VACCINE 26(17) 2127-2134 2008年4月査読有り
Contribution of interferon-beta to the immune activation induced by double-stranded DNA

H Shirota, KJ Ishii, H Takakuwa, DM Klinman

IMMUNOLOGY 118(3) 302-310 2006年7月査読有り
Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses

S Sugiura, F Goshima, H Takakuwa, T Sata, T Nakashima, Y Nishiyama

OTOLARYNGOLOGY-HEAD AND NECK SURGERY 130(4) 470-478 2004年4月査読有り

MISC

ACETYL-L-CARNITINE NORMALIZES THE IMPAIRED LONG-TERM POTENTIATION AND SPINE DENSITY IN A RAT MODEL OF GLOBAL ISCHEMIA

K. Kocsis, L. Knapp, L. Gellert, G. Olah, Z. S. Kis, H. Takakuwa, N. Iwamori, E. Ono, J. Toldi, T. Farkas

NEUROSCIENCE 269(6) 265-272 2014年6月
The characterization of low pathogenic avian influenza viruses isolated from wild birds in northern Vietnam from 2006 to 2009

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Tsuyoshi Yamaguchi, Toshihiro Ito …

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES 36(6) 581-590 2013年12月
The characterization of low pathogenic avian influenza viruses isolated from wild birds in northern Vietnam from 2006 to 2009

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Tsuyoshi Yamaguchi, Toshihiro Ito …

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES 36(6) 581-590 2013年12月
Resistance to influenza A virus infection in transformed cell lines expressing an anti-PB2 monoclonal antibody

Yoshikazu Fujimoto, Kinuyo Ozaki, Masahiro Maeda, Ken-ichi Nishijima, Hiroki Takakuwa, Koichi Otsuki, Hiroshi Kida, Etsuro Ono

VETERINARY JOURNAL 198(2) 487-493 2013年11月
Antibody survey on avian influenza viruses using egg yolks of ducks in Hanoi between 2010 and 2012

Kozue Hotta, Hiroki Takakuwa, Toshiyo Yabuta, Trang T. H. Ung, Tatsufumi Usui, Hang L. K. Nguyen, Thanh T. Le, Mai Q. Le, Tsuyoshi Yamaguchi, Koichi Otsuki …

VETERINARY MICROBIOLOGY 166(1-2) 179-183 2013年9月
Isolation and characterization of H6N1 and H9N2 avian influenza viruses from Ducks in Hanoi, Vietnam

Kozue Hotta, Hiroki Takakuwa, Quynh Mai Thi Le, Song Lien Phuong, Toshiyuki Murase, Etsuro Ono, Toshihiro Ito, Koichi Otsuki, Tetsu Yamashiro

VIRUS RESEARCH 163(2) 448-453 2012年2月
Molecular epidemiology of avian influenza viruses circulating among healthy poultry flocks in farms in northern Vietnam

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Masami Morimatsu, Yukiko Tomioka …

PREVENTIVE VETERINARY MEDICINE 103(2-3) 192-200 2012年2月
Characterization of H5N1 highly pathogenic avian influenza virus strains isolated from migratory waterfowl in Mongolia on the way back from the southern Asia to their northern territory

Yoshihiro Sakoda, Sengee Sugar, Damdinjav Batchluun, Tseren-Ochir Erdene-Ochir, Masatoshi Okamatsu, Norikazu Isoda, Kosuke Soda, Hiroki Takakuwa, Yoshimi Tsuda, Naoki Yamamoto …

VIROLOGY 406(1) 88-94 2010年10月
Development of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay for Detection of Avian Influenza Viruses in Field Specimens

Sakar Shivakoti, Hiroshi Ito, Toshiyuki Murase, Etsuro Ono, Hiroki Takakuwa, Tetsu Yamashiro, Koichi Otsuki, Toshihiro Ito

JOURNAL OF VETERINARY MEDICAL SCIENCE 72(4) 519-523 2010年4月
Development of a new disinfectant with very strong anti-influenza viral activity: A preliminary report

Hiroki Takakuwa, Toshiyuki Maruoka, Tadayo Hata, Masaaki Miyazawa, Tomoyo Hata, Hitoshi Toshimori, Koichi Otsuki

Environmental Health and Preventive Medicine 15(2) 121-123 2010年3月
Susceptibility of two species of wild terrestrial birds to infection with a highly pathogenic avian influenza virus of H5N1 subtype

Yoshikazu Fujimoto, Hiroshi Ito, Kyoko Shinya, Tsuyoshi Yamaguchi, Tatsufumi Usui, Toshiyuki Murase, Hiroichi Ozaki, Etsuro Ono, Hiroki Takakuwa, Koichi Otsuki …

AVIAN PATHOLOGY 39(2) 95-98 2010年
Possible circulation of H5N1 avian influenza viruses in healthy ducks on farms in northern Vietnam

Hiroki Takakuwa, Tetsu Yamashiro, Mai Q. Le, Lien S. Phuong, Hiroichi Ozaki, Ryota Tsunekuni, Tatsufumi Usui, Hiroshi Ito, Tsuyoshi Yamaguchi, Toshihiro Ito …

MICROBIOLOGY AND IMMUNOLOGY 54(1) 58-62 2010年1月
A vaccine prepared from a non-pathogenic H7N7 virus isolated from natural reservoir conferred protective immunity against the challenge with lethal dose of highly pathogenic avian influenza virus in chickens

Saori Sakabe, Yoshihiro Sakoda, Yoshinari Haraguchi, Norikazu Isoda, Kosuke Soda, Hiroki Takakuwa, Kazue Saijo, Akira Sawata, Katsumi Kume, Junko Hagiwara …

VACCINE 26(17) 2127-2134 2008年4月
Contribution of interferon-β to the immune activation induced by double-stranded DNA

Shirota H, Ishii KJ, Takakuwa H, Klinman DM

Immunology 118(3) 302-310 2006年7月
Treatment of solid sarcomas in immunocompetent mice with novel, oncolytic herpes simplex viruses

S Sugiura, F Goshima, H Takakuwa, T Sata, T Nakashima, Y Nishiyama

OTOLARYNGOLOGY-HEAD AND NECK SURGERY 130(4) 470-478 2004年4月
Effective treatment of disseminated peritoneal colon cancer with new replication-competent herpes simplex viruses

H Kimata, H Takakuwa, F Goshima, O Teshigahara, A Nakao, T Kurata, T Sata, Y Nishiyama

HEPATO-GASTROENTEROLOGY 50(52) 961-966 2003年7月
Oncolytic viral therapy using a spontaneously generated herpes simplex virus type 1 variant for disseminated peritoneal tumor in immunocompetent mice

H Takakuwa, R Goshima, N Nozawa, T Yoshikawa, H Kimata, A Nakao, A Nawa, T Kurata, T Sata, Y Nishiyama

ARCHIVES OF VIROLOGY 148(4) 813-825 2003年4月
Successful protection by amantadine hydrochloride against lethal encephalitis caused by a highly neurovirulent recombinant influenza A virus in mice

Mori, I, BX Liu, MJ Hossain, H Takakuwa, T Daikoku, Y Nishiyama, H Naiki, K Matsumoto, T Yokochi, Y Kimura

VIROLOGY 303(2) 287-296 2002年11月
Identification and characterization of the UL56 gene product of herpes simplex virus type 2

T Koshizuka, F Goshima, H Takakuwa, N Nozawa, T Daikoku, O Koiwai, Y Nishiyama

JOURNAL OF VIROLOGY 76(13) 6718-6728 2002年7月
Identification and characterization of the UL7 gene product of herpes simplex virus type 2

N Nozawa, T Daikoku, Y Yamauchi, H Takakuwa, F Goshima, T Yoshikawa, Y Nishiyama

VIRUS GENES 24(3) 257-266 2002年6月

もっとみる

書籍等出版物

Wada,K.,Goshima,F.,Takakuwa,H.,Yamada,H.,Daikoku,T.and Nishiyama,Y. Identification and characterization of the UL14 gene product of herpes simplex virus type 2.

Journal of General Virology 80:2423-2431(1999)
Takakuwa,H., Ito,T.,Takada,A.,Okazaki,K.and Kida H. An attenuation mechanism of Newcastle disease vaccine strain TCND .

Archives of Virology.143:1129-43(1998)
Takakuwa,H., Ito,T.,Takada,A.,Okazaki,K.and Kida H. Potentially virulent Newcastle disease viruses are maintained in migratory waterfowl populations.

Japanese Journal of Veterinary Research.45:207-15(1998)
Murata,T.,Goshima,F.,Daikoku,T.,Inagaki,K.,Takakuwa, H.,Kato,K.and Nishiyama,Y. Mitochondrial distribution and function in herpes simplex virus-infected cells.

Journal of General Virology 81:401-406(2000)
Islam,M.-A.,Ito,T.,Takakuwa,H.,Takada,A.,Itakura,C.and Kida H. Acuquisition of pathogenicity of a Newcastle disease virus isolated from a Japanese quail by intracerebral passage in chickens.

Japanese Journal of Veterinary Research.42:147-56(1994).
Goshima,F.,Watanabe,D.,Takakuwa,H.,Wada,K.,Daikoku,T., Yamada,M.and Nishiyama,Y. Herpes simplex virus UL17 protein is associated with B capsids and colocalizes with ICP35 and VP5 in infected cells.Archives of Virology,In press.

髙桑弘樹

基本情報

研究キーワード

研究分野

経歴

学歴

論文

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

産業財産権

メニュー