伊東秀記 (Hidenori Ito) - マイポータル

基本情報

所属: 愛知県医療療育総合センター発達障害研究所分子病態研究部室長

学位: 博士（薬学）(名古屋市立大学)

J-GLOBAL ID: 200901096985673344
researchmap会員ID: 0000115011

研究キーワード

研究分野

経歴

学歴

- 1994年

名古屋市立大学, 薬学研究科
- 1992年

名古屋市立大学, 薬学部

論文

132

A p.N92K variant of the GTPase RAC3 disrupts cortical neuron migration and axon elongation.

Ryota Sugawara, Keisuke Hamada, Hidenori Ito, Marcello Scala, Hiroshi Ueda, Hidenori Tabata, Kazuhiro Ogata, Koh-Ichi Nagata

The Journal of biological chemistry 108346-108346 2025年2月25日
The p.R66W Variant in RAC3 Causes Severe Fetopathy Through Variant-Specific Mechanisms.

Ryota Sugawara, Hidenori Ito, Hidenori Tabata, Hiroshi Ueda, Marcello Scala, Koh-Ichi Nagata

Cells 13(23) 2024年12月9日
Pathophysiological significance of the p.E31G variant in RAC1 responsible for a neurodevelopmental disorder with microcephaly

Masashi Nishikawa, Shin Hayashi, Atsushi Nakayama, Yosuke Nishio, Anna Shiraki, Hidenori Ito, Kouichi Maruyama, Yukako Muramatsu, Tomoo Ogi, Seiji Mizuno …

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 167520-167520 2024年9月
Variations associated with neurodevelopmental disorders affect ARF1 function and cortical development

Tomoki Ishiguro, Mariko Noda, Masashi Nishikawa, Koh-ichi Nagata, Hidenori Ito

The Journal of Biochemistry 2024年7月25日
Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development.

Tohru Matsuki, Nanako Hamada, Hidenori Ito, Ryota Sugawara, Ikuko Iwamoto, Atsuo Nakayama, Koh-Ichi Nagata

Molecular biology reports 51(1) 106-106 2024年1月16日
Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development

Masashi Nishikawa, Tohru Matsuki, Nanako Hamada, Atsuo Nakayama, Hidenori Ito, Koh-ichi Nagata

Medical Molecular Morphology 2023年7月4日
A missense variant at the RAC1-PAK1 binding site of RAC1 inactivates downstream signaling in VACTERL association

Rie Seyama, Masashi Nishikawa, Yuri Uchiyama, Keisuke Hamada, Yuka Yamamoto, Masahiro Takeda, Takanori Ochi, Monami Kishi, Toshifumi Suzuki, Kohei Hamanaka …

Scientific Reports 13(1) 2023年6月16日査読有り
Expression analyses of Rich2/Arhgap44, a Rho family GTPase-activating protein, during mouse brain development.

Naoki Goto, Masashi Nishikawa, Hidenori Ito, Mariko Noda, Nanako Hamada, Hidenori Tabata, Makoto Kinoshita, Koh-Ichi Nagata

Developmental neuroscience 2023年1月11日
Erratic and blood vessel-guided migration of astrocyte progenitors in the cerebral cortex

Hidenori Tabata, Megumi Sasaki, Masakazu Agetsuma, Hitomi Sano, Yuki Hirota, Michio Miyajima, Kanehiro Hayashi, Takao Honda, Masashi Nishikawa, Yutaka Inaguma …

Nature Communications 13(1) 2022年11月2日査読有り
Variant-specific changes in RAC3 function disrupt corticogenesis in neurodevelopmental phenotypes

Marcello Scala, Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Tayyaba Khan, Andrea Accogli, Laura Davids, Anna Ruiz, Pietro Chiurazzi, Gabriella Cericola …

Brain 145(9) 3308-3327 2022年7月19日
Gain-of-function p.F28S variant in RAC3 disrupts neuronal differentiation, migration and axonogenesis during cortical development, leading to neurodevelopmental disorder.

Masashi Nishikawa, Marcello Scala, Muhammad Umair, Hidenori Ito, Ahmed Waqas, Pasquale Striano, Federico Zara, Gregory Costain, Valeria Capra, Koh-Ichi Nagata

Journal of medical genetics 60(3) 223-232 2022年5月20日
Expression analyses of Cep152, a responsible gene product for autosomal recessive primary microcephaly, during mouse brain development.

Nanako Hamada, Mariko Noda, Hidenori Ito, Ikuko Iwamoto, Koh-Ichi Nagata

Developmental neuroscience 2022年3月8日
Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes.

Masashi Nishikawa, Hidenori Ito, Hidenori Tabata, Hiroshi Ueda, Koh-Ichi Nagata

Cells 11(4) 2022年2月16日
Functions of CNKSR2 and Its Association with Neurodevelopmental Disorders.

Hidenori Ito, Koh-Ichi Nagata

Cells 11(2) 2022年1月17日
Expression Analyses of Rac3, a Rho Family Small GTPase, during Mouse Brain Development.

Masashi Nishikawa, Hidenori Ito, Mariko Noda, Nanako Hamada, Hidenori Tabata, Koh-Ichi Nagata

Developmental neuroscience 44(1) 49-58 2022年
The synaptic scaffolding protein CNKSR2 interacts with CYTH2 to mediate hippocampal granule cell development.

Hidenori Ito, Rika Morishita, Mariko Noda, Tomoki Ishiguro, Masashi Nishikawa, Koh-Ichi Nagata

The Journal of biological chemistry 297(6) 101427-101427 2021年12月
Physiological significance of WDR45, a responsible gene for β-propeller protein associated neurodegeneration (BPAN), in brain development.

Mariko Noda, Hidenori Ito, Koh-Ichi Nagata

Scientific reports 11(1) 22568-22568 2021年11月19日
Expression analyses of PLEKHG2, a Rho family-specific guanine nucleotide exchange factor, during mouse brain development.

Masashi Nishikawa, Hidenori Ito, Mariko Noda, Nanako Hamada, Hidenori Tabata, Koh-Ichi Nagata

Medical molecular morphology 54(2) 146-155 2021年6月
Biochemical and morphological characterization of SEPT1 in mouse brain

Hidenori Ito, Rika Morishita, Mariko Noda, Ikuko Iwamoto, Koh-ichi Nagata

Medical Molecular Morphology 53(4) 221-228 2020年12月
Neuropathophysiological significance of the c.1449T>C/p.(Tyr64Cys) mutation in the CDC42 gene responsible for Takenouchi-Kosaki syndrome

Nanako Hamada, Hidenori Ito, Yukinao Shibukawa, Rika Morishita, Ikuko Iwamoto, Nobuhiko Okamoto, Koh-ichi Nagata

Biochemical and Biophysical Research Communications 529(4) 1033-1037 2020年9月査読有り