田島陽一 (Youichi Tajima) - マイポータル - researchmap

基本情報

学位: 博士(医学)

J-GLOBAL ID: 200901049520663964
researchmap会員ID: 0000150066

外部リンク: http://www.rinshoken.or.jp/

研究キーワード

8

経歴

6

1997年 - 現在

東京都臨床医学総合研究所研究員
1994年 - 1997年

Postdoctral Fellow:Memorial Sloan-Kettering
1994年 - 1997年

Postdoctral Fellow:Memorial Sloan-Kettering
Cancer Center
Cancer Center
財団法人東京都医学研究機構東京都臨床医学総合研究所生命情報研究部門, 研究員

学歴

2

MISC

17

Cloning and expression of a novel galactoside β1,3- glucuronyltransferase involved in the biosynthesis of HNK-1 epitope

Yasushi Shimoda, Youichi Tajima, Takashi Nagase, Kiyonori Harii, Noriko Osumi, Yutaka Sanai

Journal of Biological Chemistry 274(24) 17115-17122 1999年6月11日
The W (sh), W(57), and Ph Kit Expression Mutations Define Tissue-Specific Control Elements Located Between -23 and -154 kb Upstream of Kit.

Blood, 94, (8), 2658-2666, (1999)
Switching of mouse spermatogonial proliferation from the c-kit receptor-independent type to the receptor-dependent type during differentiation.

J. Reprod. Fertil., 102, 117-122, (1994)
Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: The Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis.

J. Exp. Med., 187, (9), 1451-1461, (1998)
Molecular cloning of novel Ca2+ binding protein (Calmegin) specifically expressed during male meiotic germ cell development.

J. Biol. Chem., 269, 7744-7749, (1994)
Ganglioside GT1b shows binding to p58 in rat brain, which is brain-specific sodium-dependent inorganic cotransporter: Expression cloning with a specific monoclonal antibody to ganglioside GT1b-binding protein.

J. Biochem., in press.
Effects of hormones, cyclic AMP analogues, and growht factors on steel factor (SF) production in mouse Sertoli cell cultures.

J. Reprod. Fertil., 99, 571-575, (1993)
Conseqences of exclusive expression in vivo of kit-ligand lacking the major proteolytic cleavage site.

Proc. Natl. Acad. Sci. USA, 95, 11903-11908, (1998)
Biologically active kit ligand growth factor is produced by mouse Sertoli cells and is defective in Sld mutant mice.

Development, 113, 1031-1035, (1991)
The W (sh), W(57), and Ph Kit Expression Mutations Define Tissue-Specific Control Elements Located Between -23 and -154 kb Upstream of Kit.

Blood, 94, (8), 2658-2666, (1999)
Switching of mouse spermatogonial proliferation from the c-kit receptor -independent type to the receptor-dependent type during differentiation.

J. Reprod. Fertil., 102, 117-122, (1994)
Role of dimerization of the membrane-associated growth factor kit ligand in juxtacrine signaling: The Sl17H mutation affects dimerization and stability-phenotypes in hematopoiesis.

J. Exp. Med., 187, (9), 1451-1461, (1998)
Molecular cloning of novel Ca2+ binding protein (Calmegin) specifically expressed during male meiotic germ cell development.

J. Biol. Chem., 269, 7744-7749, (1994)
Ganglioside GT1b shows binding to p58 in rat brain, which is brain-specific sodium-dependent inorganic cotransporter: Expression cloning with a specific monoclonal antibody to ganglioside GT1b-binding protein.

J. Biochem., in press.
Effects of hormones, cyclic AMP analogues, and growht factors on steel factor (SF) production in mouse Sertoli cell cultures.

J. Reprod. Fertil., 99, 571-575, (1993)
Conseqences of exclusive expression in vivo of kit-ligand lacking the major proteolytic cleavage site.

Proc. Natl. Acad. Sci. USA, 95, 11903-11908, (1998)
Biologically active kit ligand growth factor is produced by mouse Sertoli cells and is defective in Sld mutant mice.

Development, 113, 1031-1035, (1991)

所属学協会

2

共同研究・競争的資金等の研究課題

1

糖転移酵素遺伝子のクローニング、糖転移様遺伝子LARGEの機能解析、 MFG-E8の機能解析、神経特異的プロテオグリカンの精製および解析