In this study, a series of validations of a weakly one-way CFD-FEA coupling method for the estimation of the dynamic response of a container ship under severe wave condition is made. By comparing the prediction with linear/non-linear strip method, 3D panel method and towing tank test results under various wave conditions in terms of rigid body motions and structural loads, the effectiveness of the CFD-FEA coupling method is confirmed. Furthermore, the hydro-elastic behavior obtained by 3D panel method and the CFD-FEA coupling method are validated regarding the. whipping moment by comparing the experiment.