J-GLOBAL         Last updated: Jun 19, 2019 at 10:17
RIKEN Center for Sustainable Resource Science
(BLANK)(The University of Tokyo)

Research Areas


Academic & Professional Experience

Apr 2017
Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Apr 2013
Group Director, Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Science
Apr 2002
Mar 2018
Chief Scientist, Chemical Genetics Laboratory, RIKEN
Jan 1995
Mar 2002
Assosiate Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo
May 1986
Dec 1994
Assistant Professor, Faculty of Agriculture, The University of Tokyo

Awards & Honors

Dec 2018
Basic studies on molecular target drug discovery based on epigenetic regulation, The Japan Medical Research and Development Grand Prize, the Healthcare Policy Minister's Prize, Cabinet Secretariat, Office of Healthcare Policy
Feb 2017
Chemical biology on cancer therapy targeting regulatory molecules of epigenetics, Princess Takamatsu Cancer Research Fund Prizes, Princess Takamatsu Cancer Research Fund
Jun 2015
Studies on Regulation of Eukaryotic Gene Expression using Bioactive Microbial Metabolites and their Application to Drug Discovery, Japan Academy Prize, The Japan Academy
Jun 2013
Tsuruo Takashi Award, The Japanese Association for Molecular Target Therapy of Cancer
Nov 2012
Opening new frontiers through chemical genetics of natural products, Lectureship Award, Charles E. Dohme Memorial Lecture 2012, Johns Hopkins University
Mar 2012
Significant Achievement Award for Achievement Worthy of Distinguished Award, RIKEN
May 2011
Japan Society for Bioscience, Biotechnology, and Agrochemistry Award, Japan Society for Bioscience, Biotechnology, and Agrochemistry
Apr 2010
Prizes for Science and Technology, Minister of Education, Culture, Sports, Science and Technology
Oct 2009
Japan Bioindustry Association Award, Japan Bioindustry Association
Nov 1998
Sumiki-Umezawa Memorial Award, Japan Antibiotics Research Association

Published Papers

Ling F, Bradshaw E, Yoshida M
Scientific Reports   9(5433) s41598-019-41699-9   Apr 2019   [Refereed]
Ali T FS, Ciftci HI, Radwan M O, Koga R, Ohsugi T, Okiyama Y, Honma T, Nakata A, Ito A, Yoshida M, Fujita M, Otsuka M
Bioorganic & Medicinal Chemistry   27 1767-1775   Mar 2019   [Refereed]
Yoshida A, Yoshida M, Kuzuyama T, Nishiyama M, Kosono S
Extremophiles   s00792-019-01090-y   Mar 2019   [Refereed]
Shirai F, Tsumura T, Yashiroda Y, Yuki H, Niwa H, Sato S, Chikada T, Koda Y, Washizuka K, Yoshimoto N, Abe M, Onuki T, Mazaki Y, Hirama C, Fukami T1, Watanabe H, Honma T, Umehara T, Shirouzu M, Okue M, Kano Y, Watanabe T, Kitamura K, Shitara E, Muramatsu Y, Yoshida H, Mizutani A, Seimiya H, Yoshida M, Koyama H.
J Med Chem.   62 3407-3427   Mar 2019   [Refereed]
Shinohara H, Yasue N, Onuki T, Kondoh Y, Yoshida M, Matsubayashi Y
Communications Biology   2(61) S42003-019-0307-8   Feb 2019   [Refereed]
Simpkins SW, Deshpande R, Nelson J, Li SC, Piotrowski JS, Ward H., Yashiroda Y, Osada H, Yoshida M, Boone C, Myers CL
Nature Protocols   14(2) 415-440   Feb 2019   [Refereed]
Yoshida M
Bioscience, biotechnology, and biochemistry   83(1) 1-9   Jan 2019   [Refereed]
Cornelio K, Espiritu RA, Hanashima S, Todokoro Y, Malabed R, Kinoshita M, Matsumori N, Murata M, Nishimura S, Kakeya H, Yoshida M, Matsunaga S
Biochimica et biophysica acta. Biomembranes   1861(1) 228-235   Jan 2019   [Refereed]
Mizutani A, Yashiroda Y, Muramatsu Y, Yoshida H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H
Cancer science   109(12) 4003-4014   Dec 2018   [Refereed]
Robaa D, Monaldi D, Wössner N, Kudo N, Rumpf T, Schiedel M, Yoshida M, Jung M
Chemical record (New York, N.Y.)   18(12) 1701-1707   Dec 2018   [Refereed]


Effects of trichostatins on differentiation of murine erythroleukemia cells
Cancer Reseach   47    1987
Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A
Journal of Biological Chemistry   265    1990

Conference Activities & Talks

Translational buffering linking splicing and cancer [Invited]
CIFAR Genetic Networks Program Meeting   1 Apr 2019   
Analysis of molecular mechanisms underlying nucleophagy in Aspergillus oryzae
27 Mar 2019   
Functional analysis of PQ-loop proteins in Aspergillus oryzae
27 Mar 2019   
Translational buffering: consequent to splicing inhibition
Chhipi Shrestha Jagat Krishna, Schneider-Poetsch Tilman, Iwasaki Shintaro, Yoshida Minoru
26 Mar 2019   
Development of fluorescent probes using HP1α chromodomain and imaging of chromatin dynamics
26 Mar 2019   

Research Grants & Projects

Screening for cell cycle inhibitors
Project Year: 1986 - 2002
Chemical genetic studies on localization and modification of nuclear factors
JST Basic Research Programs (Core Research for Evolutional Science and Technology :CREST)
Project Year: 1999   
Analysis of protein nuclear transport using a nuclear export inhibitor, leptomycin
Project Year: 1990   
Analysis of transcriptional control by histone acetylation using a specific histone deacetylase inhibitor, trichostatin A.
Project Year: 1986